{"hash":"2169939623230314926","title":"ER protein folding and quality control","description":"The proteins in this cluster predominantly relate to the unfolded protein response, ER stress, and the handling of misfolded proteins (ER chaperone activity, ERAD, and translocation to the ER membrane), which together describe ER-associated protein folding and quality control. While a few terms (e.g., DNA replication) are present, the dominant signal is ER-focused protein maintenance and surveillance.","confidence":"High","size":5,"edges":9,"triangles":7,"max_degree":4,"top_function":"DNA replication","members":[{"accession":"NP_001257747.1","go_terms":["GO:0008363"]},{"accession":"XP_006564598.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_026297955.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_026297956.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_006571188.1","go_terms":["GO:0046944"]}],"graph":[["XP_006571188.1","XP_006564598.1",0.704],["XP_006571188.1","XP_026297955.1",0.784],["XP_006571188.1","XP_026297956.1",0.813],["NP_001257747.1","XP_006564598.1",0.784],["NP_001257747.1","XP_026297955.1",0.82],["NP_001257747.1","XP_026297956.1",0.798],["XP_026297955.1","XP_006564598.1",0.87],["XP_026297955.1","XP_026297956.1",0.883],["XP_006564598.1","XP_026297956.1",0.855]],"all_go_terms":{"GO:0008363":1,"GO:0031204":3,"GO:0070389":3,"GO:0030433":3,"GO:0090084":3,"GO:0006986":3,"GO:0070843":3,"GO:0051259":3,"GO:0006260":3,"GO:0036494":3,"GO:1901621":3,"GO:0009408":3,"GO:0097428":3,"GO:0045454":3,"GO:0071630":3,"GO:0046825":3,"GO:0001707":3,"GO:0034975":3,"GO:0006452":3,"GO:0006469":3,"GO:0071374":3,"GO:0035719":3,"GO:0006458":3,"GO:1900035":3,"GO:0032781":3,"GO:0006626":3,"GO:0046944":1},"recipe_readded":[]}