{"hash":"952889176081602254","title":"Ribosome biogenesis and translation","description":"This cluster centers on ribosome biogenesis and translation: rRNA maturation and pseudouridine synthesis, large subunit assembly, and cytoplasmic translation, with additional RNA processing links such as spliceosome-related regulation.","confidence":"High","size":23,"edges":246,"triangles":1634,"max_degree":22,"top_function":"ribosome biogenesis","members":[{"accession":"NP_001094622.1","go_terms":["GO:0031564","GO:0045903","GO:0006353","GO:0006412","GO:1990145","GO:0046677","GO:0006351","GO:0045947","GO:0006437","GO:0034605","GO:0000455","GO:0042254"]},{"accession":"NP_001106780.1","go_terms":["GO:0042474","GO:0007605","GO:0048318","GO:0001501","GO:0001503","GO:0034463","GO:0006412"]},{"accession":"NP_001107993.1","go_terms":["GO:0031118","GO:0031120","GO:0042254","GO:1904874","GO:0000469","GO:0007004"]},{"accession":"NP_776880.1","go_terms":["GO:0010458","GO:0042273","GO:0060041","GO:0032781","GO:1902626","GO:0021554","GO:0007093","GO:0031290","GO:0006412","GO:0000027"]},{"accession":"NP_777229.1","go_terms":["GO:0006412"]},{"accession":"NP_788838.1","go_terms":["GO:0075522","GO:0072752","GO:0007053","GO:1990928","GO:0034414","GO:1903608","GO:0038202","GO:0006396","GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_002688978.2","go_terms":["GO:0000266","GO:0048140","GO:1990182","GO:0001731","GO:0075522","GO:0016559","GO:0043161","GO:0035871","GO:0070452","GO:0070537","GO:0006281","GO:0000338","GO:0006446","GO:0045471","GO:0010387","GO:0035522","GO:0010950","GO:0014067","GO:0000393","GO:0034286","GO:0051726","GO:1902906","GO:0000398","GO:1903894"]},{"accession":"XP_024844508.1","go_terms":["GO:0000028","GO:0000462","GO:0006412"]},{"accession":"XP_059733228.1","go_terms":["GO:0006412"]},{"accession":"XP_059735263.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"XP_059736563.1","go_terms":["GO:0045787","GO:0006417","GO:0009615","GO:0006412"]},{"accession":"XP_059744640.1","go_terms":[]},{"accession":"NP_001012700.1","go_terms":["GO:0032147","GO:0042254","GO:0006614","GO:0071353","GO:0002181","GO:0000027"]},{"accession":"NP_001014409.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"NP_001015531.1","go_terms":["GO:0006450","GO:0006412","GO:0006407"]},{"accession":"NP_001015647.1","go_terms":["GO:0000470","GO:0006417","GO:0006412"]},{"accession":"NP_001020488.1","go_terms":["GO:0070966","GO:0071025","GO:0035167","GO:0070481","GO:0000462","GO:0000463","GO:0000466","GO:0006415","GO:0006413","GO:0006412"]},{"accession":"NP_001026926.1","go_terms":["GO:0002181","GO:0000027","GO:0006412"]},{"accession":"NP_001029631.1","go_terms":["GO:0042255","GO:0046677","GO:0000448","GO:0006412"]},{"accession":"NP_001035671.1","go_terms":["GO:0042274","GO:0000461","GO:0048542","GO:0000447","GO:0006412"]},{"accession":"NP_001068888.1","go_terms":["GO:0007029","GO:1904751","GO:0000055","GO:0015768"]},{"accession":"NP_001070466.1","go_terms":["GO:1901194","GO:0006412"]},{"accession":"NP_001076868.1","go_terms":["GO:0006614","GO:0071353","GO:0042254","GO:0002181","GO:0000027"]}],"graph":[["NP_001107993.1","XP_024844508.1",0.767],["NP_001107993.1","XP_059733228.1",0.75],["NP_001107993.1","XP_059735263.1",0.712],["NP_001107993.1","XP_059736563.1",0.666],["NP_001107993.1","XP_059744640.1",0.738],["NP_001107993.1","NP_001012700.1",0.767],["NP_001107993.1","NP_001014409.1",0.71],["NP_001107993.1","NP_001015531.1",0.671],["NP_001107993.1","NP_001015647.1",0.721],["NP_001107993.1","NP_001020488.1",0.694],["NP_001107993.1","NP_001026926.1",0.726],["NP_001107993.1","NP_001029631.1",0.656],["NP_001107993.1","NP_001035671.1",0.767],["NP_001107993.1","NP_001068888.1",0.671],["NP_001107993.1","NP_001070466.1",0.709],["NP_001107993.1","NP_001076868.1",0.829],["NP_001107993.1","NP_001094622.1",0.707],["NP_001107993.1","NP_001106780.1",0.712],["NP_001107993.1","NP_776880.1",0.699],["NP_001107993.1","NP_777229.1",0.713],["NP_001107993.1","NP_788838.1",0.783],["NP_001107993.1","XP_002688978.2",0.624],["NP_001035671.1","NP_001012700.1",0.745],["NP_001035671.1","NP_001014409.1",0.797],["NP_001035671.1","NP_001015531.1",0.731],["NP_001035671.1","NP_001015647.1",0.837],["NP_001035671.1","NP_001020488.1",0.727],["NP_001035671.1","NP_001026926.1",0.744],["NP_001035671.1","NP_001029631.1",0.748],["NP_001035671.1","NP_001076868.1",0.802],["NP_001035671.1","NP_001070466.1",0.721],["NP_001035671.1","NP_001068888.1",0.78],["NP_001035671.1","NP_776880.1",0.646],["NP_001035671.1","NP_777229.1",0.701],["NP_001035671.1","NP_001106780.1",0.673],["NP_001035671.1","NP_001094622.1",0.715],["NP_001035671.1","XP_002688978.2",0.556],["NP_001035671.1","NP_788838.1",0.613],["NP_001035671.1","XP_059744640.1",0.71],["NP_001035671.1","XP_059736563.1",0.743],["NP_001035671.1","XP_059733228.1",0.711],["NP_001035671.1","XP_059735263.1",0.777],["NP_001035671.1","XP_024844508.1",0.802],["NP_776880.1","NP_788838.1",0.717],["NP_776880.1","XP_002688978.2",0.676],["NP_776880.1","XP_024844508.1",0.796],["NP_776880.1","XP_059733228.1",0.755],["NP_776880.1","XP_059735263.1",0.782],["NP_776880.1","XP_059736563.1",0.809],["NP_776880.1","XP_059744640.1",0.767],["NP_776880.1","NP_001012700.1",0.726],["NP_776880.1","NP_001014409.1",0.829],["NP_776880.1","NP_001015531.1",0.81],["NP_776880.1","NP_001015647.1",0.833],["NP_776880.1","NP_001020488.1",0.865],["NP_776880.1","NP_001026926.1",0.802],["NP_776880.1","NP_001029631.1",0.749],["NP_776880.1","NP_001068888.1",0.747],["NP_776880.1","NP_001070466.1",0.742],["NP_776880.1","NP_001076868.1",0.818],["NP_776880.1","NP_001094622.1",0.797],["NP_776880.1","NP_001106780.1",0.703],["NP_776880.1","NP_777229.1",0.7],["XP_059735263.1","NP_001094622.1",0.836],["XP_059735263.1","NP_001106780.1",0.807],["XP_059735263.1","NP_777229.1",0.686],["XP_059735263.1","NP_788838.1",0.666],["XP_059735263.1","XP_002688978.2",0.536],["XP_059735263.1","XP_024844508.1",0.695],["XP_059735263.1","XP_059744640.1",0.72],["XP_059735263.1","XP_059733228.1",0.682],["XP_059735263.1","XP_059736563.1",0.778],["XP_059735263.1","NP_001012700.1",0.752],["XP_059735263.1","NP_001014409.1",0.764],["XP_059735263.1","NP_001015531.1",0.769],["XP_059735263.1","NP_001015647.1",0.813],["XP_059735263.1","NP_001020488.1",0.729],["XP_059735263.1","NP_001026926.1",0.812],["XP_059735263.1","NP_001029631.1",0.733],["XP_059735263.1","NP_001068888.1",0.757],["XP_059735263.1","NP_001070466.1",0.816],["XP_059735263.1","NP_001076868.1",0.811],["NP_001076868.1","NP_001012700.1",0.746],["NP_001076868.1","NP_001014409.1",0.707],["NP_001076868.1","NP_001015531.1",0.726],["NP_001076868.1","NP_001015647.1",0.78],["NP_001076868.1","NP_001020488.1",0.778],["NP_001076868.1","NP_001026926.1",0.818],["NP_001076868.1","NP_001029631.1",0.784],["NP_001076868.1","NP_001068888.1",0.63],["NP_001076868.1","NP_001070466.1",0.733],["NP_001076868.1","NP_777229.1",0.769],["NP_001076868.1","NP_001106780.1",0.806],["NP_001076868.1","NP_001094622.1",0.809],["NP_001076868.1","NP_788838.1",0.807],["NP_001076868.1","XP_059744640.1",0.545],["NP_001076868.1","XP_059736563.1",0.784],["NP_001076868.1","XP_059733228.1",0.731],["NP_001076868.1","XP_024844508.1",0.81],["NP_001094622.1","XP_024844508.1",0.779],["NP_001094622.1","XP_059733228.1",0.656],["NP_001094622.1","XP_059736563.1",0.842],["NP_001094622.1","XP_059744640.1",0.871],["NP_001094622.1","NP_001012700.1",0.752],["NP_001094622.1","NP_001014409.1",0.835],["NP_001094622.1","NP_001015531.1",0.81],["NP_001094622.1","NP_001015647.1",0.806],["NP_001094622.1","NP_001020488.1",0.768],["NP_001094622.1","NP_001026926.1",0.81],["NP_001094622.1","NP_001029631.1",0.776],["NP_001094622.1","NP_001068888.1",0.753],["NP_001094622.1","NP_001070466.1",0.822],["NP_001094622.1","NP_001106780.1",0.686],["NP_001094622.1","NP_777229.1",0.646],["NP_001094622.1","NP_788838.1",0.686],["NP_001094622.1","XP_002688978.2",0.616],["NP_001015647.1","NP_001012700.1",0.754],["NP_001015647.1","NP_001014409.1",0.848],["NP_001015647.1","NP_001015531.1",0.79],["NP_001015647.1","NP_001020488.1",0.862],["NP_001015647.1","NP_001026926.1",0.852],["NP_001015647.1","NP_001029631.1",0.787],["NP_001015647.1","NP_001068888.1",0.726],["NP_001015647.1","NP_001070466.1",0.742],["NP_001015647.1","NP_001106780.1",0.84],["NP_001015647.1","NP_777229.1",0.777],["NP_001015647.1","NP_788838.1",0.685],["NP_001015647.1","XP_002688978.2",0.515],["NP_001015647.1","XP_024844508.1",0.841],["NP_001015647.1","XP_059733228.1",0.79],["NP_001015647.1","XP_059736563.1",0.798],["NP_001015647.1","XP_059744640.1",0.751],["XP_059744640.1","NP_777229.1",0.855],["XP_059744640.1","NP_788838.1",0.701],["XP_059744640.1","XP_002688978.2",0.62],["XP_059744640.1","XP_024844508.1",0.884],["XP_059744640.1","XP_059733228.1",0.854],["XP_059744640.1","XP_059736563.1",0.865],["XP_059744640.1","NP_001012700.1",0.663],["XP_059744640.1","NP_001014409.1",0.866],["XP_059744640.1","NP_001015531.1",0.552],["XP_059744640.1","NP_001020488.1",0.637],["XP_059744640.1","NP_001026926.1",0.604],["XP_059744640.1","NP_001029631.1",0.632],["XP_059744640.1","NP_001068888.1",0.516],["XP_002688978.2","NP_777229.1",0.75],["XP_002688978.2","NP_788838.1",0.632],["XP_002688978.2","XP_059736563.1",0.738],["XP_002688978.2","XP_059733228.1",0.742],["XP_002688978.2","XP_024844508.1",0.581],["XP_002688978.2","NP_001012700.1",0.643],["XP_002688978.2","NP_001014409.1",0.61],["XP_002688978.2","NP_001015531.1",0.572],["XP_002688978.2","NP_001020488.1",0.704],["XP_002688978.2","NP_001026926.1",0.658],["XP_002688978.2","NP_001106780.1",0.664],["NP_001070466.1","NP_001012700.1",0.632],["NP_001070466.1","NP_001014409.1",0.776],["NP_001070466.1","NP_001015531.1",0.757],["NP_001070466.1","NP_001020488.1",0.781],["NP_001070466.1","NP_001026926.1",0.816],["NP_001070466.1","NP_001029631.1",0.723],["NP_001070466.1","NP_001068888.1",0.703],["NP_001070466.1","NP_777229.1",0.665],["NP_001070466.1","NP_001106780.1",0.631],["NP_001070466.1","XP_059736563.1",0.721],["NP_001070466.1","XP_059733228.1",0.725],["NP_001070466.1","XP_024844508.1",0.726],["NP_788838.1","NP_777229.1",0.742],["NP_788838.1","XP_024844508.1",0.741],["NP_788838.1","XP_059733228.1",0.825],["NP_788838.1","XP_059736563.1",0.814],["NP_788838.1","NP_001012700.1",0.757],["NP_788838.1","NP_001014409.1",0.762],["NP_788838.1","NP_001015531.1",0.703],["NP_788838.1","NP_001020488.1",0.727],["NP_788838.1","NP_001026926.1",0.757],["NP_788838.1","NP_001029631.1",0.735],["NP_788838.1","NP_001068888.1",0.651],["NP_788838.1","NP_001106780.1",0.768],["NP_001029631.1","NP_001012700.1",0.722],["NP_001029631.1","NP_001014409.1",0.786],["NP_001029631.1","NP_001015531.1",0.72],["NP_001029631.1","NP_001020488.1",0.81],["NP_001029631.1","NP_001026926.1",0.793],["NP_001029631.1","NP_001068888.1",0.767],["NP_001029631.1","NP_777229.1",0.599],["NP_001029631.1","NP_001106780.1",0.667],["NP_001029631.1","XP_059736563.1",0.739],["NP_001029631.1","XP_059733228.1",0.618],["NP_001029631.1","XP_024844508.1",0.74],["NP_001068888.1","NP_001012700.1",0.68],["NP_001068888.1","NP_001014409.1",0.771],["NP_001068888.1","NP_001015531.1",0.824],["NP_001068888.1","NP_001020488.1",0.754],["NP_001068888.1","NP_001026926.1",0.8],["NP_001068888.1","NP_001106780.1",0.702],["NP_001068888.1","NP_777229.1",0.832],["NP_001068888.1","XP_024844508.1",0.785],["NP_001068888.1","XP_059733228.1",0.891],["NP_001068888.1","XP_059736563.1",0.776],["NP_001012700.1","NP_001014409.1",0.747],["NP_001012700.1","NP_001015531.1",0.687],["NP_001012700.1","NP_001020488.1",0.769],["NP_001012700.1","NP_001026926.1",0.791],["NP_001012700.1","NP_001106780.1",0.721],["NP_001012700.1","NP_777229.1",0.786],["NP_001012700.1","XP_024844508.1",0.795],["NP_001012700.1","XP_059733228.1",0.724],["NP_001012700.1","XP_059736563.1",0.717],["NP_001015531.1","NP_001014409.1",0.73],["NP_001015531.1","NP_001020488.1",0.775],["NP_001015531.1","NP_001026926.1",0.797],["NP_001015531.1","NP_001106780.1",0.685],["NP_001015531.1","NP_777229.1",0.619],["NP_001015531.1","XP_024844508.1",0.751],["NP_001015531.1","XP_059733228.1",0.637],["NP_001015531.1","XP_059736563.1",0.726],["NP_777229.1","XP_024844508.1",0.723],["NP_777229.1","XP_059733228.1",0.708],["NP_777229.1","XP_059736563.1",0.659],["NP_777229.1","NP_001014409.1",0.697],["NP_777229.1","NP_001020488.1",0.689],["NP_777229.1","NP_001026926.1",0.691],["NP_777229.1","NP_001106780.1",0.686],["XP_059736563.1","NP_001106780.1",0.697],["XP_059736563.1","XP_024844508.1",0.816],["XP_059736563.1","XP_059733228.1",0.698],["XP_059736563.1","NP_001014409.1",0.776],["XP_059736563.1","NP_001020488.1",0.765],["XP_059736563.1","NP_001026926.1",0.771],["XP_059733228.1","NP_001106780.1",0.688],["XP_059733228.1","XP_024844508.1",0.779],["XP_059733228.1","NP_001014409.1",0.742],["XP_059733228.1","NP_001020488.1",0.677],["XP_059733228.1","NP_001026926.1",0.69],["NP_001026926.1","NP_001014409.1",0.84],["NP_001026926.1","NP_001020488.1",0.825],["NP_001026926.1","NP_001106780.1",0.724],["NP_001026926.1","XP_024844508.1",0.808],["NP_001106780.1","XP_024844508.1",0.708],["NP_001106780.1","NP_001014409.1",0.809],["NP_001106780.1","NP_001020488.1",0.72],["XP_024844508.1","NP_001014409.1",0.756],["XP_024844508.1","NP_001020488.1",0.841],["NP_001014409.1","NP_001020488.1",0.859]],"all_go_terms":{"GO:0031564":1,"GO:0006412":16,"GO:0045947":1,"GO:1990145":1,"GO:0046677":2,"GO:0006351":1,"GO:0034605":1,"GO:0042254":6,"GO:0006437":1,"GO:0000455":1,"GO:0006353":1,"GO:0045903":1,"GO:0001501":1,"GO:0007605":1,"GO:0042474":1,"GO:0048318":1,"GO:0034463":1,"GO:0001503":1,"GO:0031118":3,"GO:0007004":1,"GO:1904874":1,"GO:0031120":3,"GO:0000469":1,"GO:1902626":1,"GO:0000027":4,"GO:0032781":1,"GO:0031290":1,"GO:0042273":1,"GO:0007093":1,"GO:0021554":1,"GO:0060041":1,"GO:0010458":1,"GO:0034414":1,"GO:0048255":1,"GO:0001825":1,"GO:0010610":1,"GO:0006446":2,"GO:1900363":1,"GO:0006376":1,"GO:1990928":1,"GO:0001731":2,"GO:0006396":1,"GO:0002188":1,"GO:0035278":1,"GO:0031047":1,"GO:1903608":1,"GO:0034462":1,"GO:1903586":1,"GO:0060211":1,"GO:0048026":1,"GO:0000380":1,"GO:0016556":1,"GO:0048025":3,"GO:1905663":1,"GO:0038202":1,"GO:0000381":1,"GO:0075522":2,"GO:1902625":1,"GO:0097010":1,"GO:0072752":1,"GO:0007053":1,"GO:1901407":1,"GO:0075525":1,"GO:0006378":1,"GO:0006406":1,"GO:0045292":1,"GO:0048140":1,"GO:0035522":1,"GO:0010950":1,"GO:0035871":1,"GO:0070452":1,"GO:0014067":1,"GO:0000393":1,"GO:0000266":1,"GO:0070537":1,"GO:0000338":1,"GO:1902906":1,"GO:0045471":1,"GO:0010387":1,"GO:0043161":1,"GO:0000398":1,"GO:0016559":1,"GO:1903894":1,"GO:0051726":1,"GO:0006281":1,"GO:0034286":1,"GO:1990182":1,"GO:0000028":1,"GO:0000462":2,"GO:0000185":2,"GO:0000470":3,"GO:1904571":2,"GO:0046330":2,"GO:2000623":2,"GO:0007338":2,"GO:0001682":2,"GO:1900745":2,"GO:0000492":2,"GO:0006417":2,"GO:0045787":1,"GO:0009615":1,"GO:0071353":2,"GO:0032147":1,"GO:0002181":3,"GO:0006614":2,"GO:0006450":1,"GO:0006407":1,"GO:0006413":1,"GO:0035167":1,"GO:0000463":1,"GO:0070966":1,"GO:0070481":1,"GO:0071025":1,"GO:0000466":1,"GO:0006415":1,"GO:0000448":1,"GO:0042255":1,"GO:0000461":1,"GO:0042274":1,"GO:0000447":1,"GO:0048542":1,"GO:0000055":1,"GO:0007029":1,"GO:0015768":1,"GO:1904751":1,"GO:1901194":1},"recipe_readded":[]}