{"hash":"509040747823704036","title":"Adaptive antiviral immune regulation","description":"The cluster is enriched for immune-related GO terms centered on antiviral defense and adaptive immunity, including defense response to virus, adaptive and humoral immune responses, and regulation of MHC class I biosynthesis. It also features regulatory actions on cytokine production (IL-5, Th2), STAT signaling, and suppression of viral genome replication, pointing to coordinated immune activation with tight regulation. The presence of inflammation/coagulation terms further supports an immune response context.","confidence":"High","size":13,"edges":78,"triangles":286,"max_degree":12,"top_function":null,"members":[{"accession":"NP_776453.1","go_terms":["GO:0033138","GO:0071222","GO:0051897","GO:0032092","GO:0030838","GO:0030851","GO:2000251","GO:0045471","GO:0014068","GO:0006955","GO:1901215","GO:0042993","GO:0050731","GO:0071345","GO:0045639","GO:0045944"]},{"accession":"NP_001232865.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"XP_002689573.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"XP_002689576.3","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"XP_010806063.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"XP_059745353.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"NP_001026935.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"XP_002689584.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"NP_001268830.1","go_terms":["GO:0042508","GO:0042502","GO:0042531","GO:0002829","GO:0045345","GO:0050778","GO:0007259","GO:0043381","GO:0032714","GO:0032696","GO:0032729","GO:0051607"]},{"accession":"NP_851340.2","go_terms":["GO:0032740","GO:0048304","GO:0030890","GO:0042104","GO:0097192","GO:0045591","GO:0051024","GO:0046013","GO:0002903","GO:0042523","GO:0050728","GO:0050672","GO:0002250","GO:0032729"]},{"accession":"XP_002689580.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"XP_010806067.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]},{"accession":"XP_059745352.1","go_terms":["GO:0007596","GO:0045071","GO:0046597","GO:0042742","GO:0033141","GO:2000552","GO:0045343","GO:0002286","GO:0030183","GO:0042517","GO:2000663","GO:2000666","GO:0002323","GO:0043330","GO:0035458","GO:0098586","GO:0045087","GO:0042100","GO:0060337","GO:0060338","GO:0006959","GO:0071549","GO:0051607","GO:0045581","GO:0007565","GO:0071359","GO:0002250","GO:0002312"]}],"graph":[["XP_002689573.1","NP_001232865.1",0.707],["XP_002689573.1","NP_001268830.1",0.659],["XP_002689573.1","NP_776453.1",0.678],[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