{"hash":"435421459337531441","title":"Amino acid transport and osmotic homeostasis","description":"This cluster is dominated by GO terms for import of multiple amino acids (arginine, methionine, lysine) across the plasma membrane, plus related transport activities (polyamines, ammonium) and osmotic/volume regulation (cell volume homeostasis, hypotonic salinity response). The common theme is membrane-mediated amino acid transport coupled to cellular osmoregulation, with arginine metabolism linking to nitric oxide production. ","confidence":"High","size":27,"edges":159,"triangles":501,"max_degree":22,"top_function":null,"members":[{"accession":"NP_001179427.1","go_terms":["GO:1901482","GO:1901481","GO:0006867","GO:0090452","GO:0090513","GO:0090515","GO:0090514","GO:0090517","GO:0090516","GO:0090518","GO:1990818","GO:0051365","GO:0048829","GO:0089707","GO:0061402","GO:0089708","GO:2000487","GO:0015824","GO:0015808"]},{"accession":"XP_010819080.1","go_terms":["GO:1901482","GO:1901481","GO:0006867","GO:0090452","GO:0090513","GO:0090515","GO:0090514","GO:0090517","GO:0090516","GO:0090518","GO:1990818","GO:0051365","GO:0048829","GO:0089707","GO:0061402","GO:0089708","GO:2000487","GO:0015824","GO:0015808"]},{"accession":"NP_001095386.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"NP_001095817.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"NP_001096710.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"NP_001129264.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"NP_001178971.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_002695390.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_005219718.4","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_005226082.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_015313851.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_015313856.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_024834632.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_024835118.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_024835121.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_024835250.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_024835251.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_059733237.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_059733588.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"NP_001077142.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_002692877.3","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_002695418.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_010813767.4","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_024835123.2","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_059733313.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"NP_001071487.1","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]},{"accession":"XP_002695413.3","go_terms":["GO:0097639","GO:0097638","GO:0006527","GO:0097640","GO:0044690","GO:0042941","GO:0042942","GO:0002537","GO:0010923","GO:0042116","GO:0043030","GO:0006809","GO:1902274","GO:0006884","GO:0098713","GO:0070634","GO:0071477","GO:1902269","GO:0015812","GO:0035826"]}],"graph":[["XP_024834632.2","XP_002695390.2",0.517],["XP_024834632.2","XP_002695413.3",0.598],["XP_024834632.2","XP_010813767.4",0.502],["XP_024834632.2","XP_015313851.2",0.603],["XP_024834632.2","XP_015313856.2",0.581],["XP_024834632.2","XP_024835123.2",0.689],["XP_024834632.2","XP_024835250.1",0.537],["XP_024834632.2","XP_059733313.1",0.557],["XP_024834632.2","XP_059733588.1",0.504],["XP_024834632.2","NP_001071487.1",0.529],["XP_024834632.2","NP_001129264.1",0.546],["NP_001129264.1","XP_059733588.1",0.522],["NP_001129264.1","NP_001071487.1",0.618],["NP_001129264.1","NP_001077142.1",0.665],["NP_001129264.1","NP_001095386.1",0.59],["NP_001129264.1","NP_001095817.1",0.51],["NP_001129264.1","NP_001178971.1",0.551],["NP_001129264.1","XP_002695390.2",0.611],["NP_001129264.1","XP_002695418.2",0.544],["NP_001129264.1","XP_005226082.2",0.566],["NP_001129264.1","XP_015313851.2",0.709],["NP_001129264.1","XP_015313856.2",0.521],["NP_001129264.1","XP_024835118.1",0.531],["NP_001129264.1","XP_024835121.2",0.505],["NP_001129264.1","XP_024835123.2",0.572],["NP_001129264.1","XP_024835250.1",0.65],["NP_001077142.1","NP_001071487.1",0.589],["NP_001077142.1","NP_001178971.1",0.616],["NP_001077142.1","NP_001096710.1",0.513],["NP_001077142.1","NP_001095817.1",0.64],["NP_001077142.1","XP_024835123.2",0.646],["NP_001077142.1","XP_024835250.1",0.536],["NP_001077142.1","XP_024835251.1",0.509],["NP_001077142.1","XP_010813767.4",0.501],["NP_001077142.1","XP_015313851.2",0.646],["NP_001077142.1","XP_015313856.2",0.505],["NP_001077142.1","XP_005226082.2",0.692],["NP_001077142.1","XP_002695390.2",0.62],["NP_001077142.1","XP_002695413.3",0.591],["NP_001077142.1","XP_002695418.2",0.605],["NP_001077142.1","XP_059733313.1",0.637],["NP_001095386.1","XP_059733237.1",0.573],["NP_001095386.1","XP_059733313.1",0.514],["NP_001095386.1","NP_001071487.1",0.56],["NP_001095386.1","NP_001178971.1",0.629],["NP_001095386.1","XP_002695390.2",0.516],["NP_001095386.1","XP_002695413.3",0.538],["NP_001095386.1","XP_002695418.2",0.537],["NP_001095386.1","XP_005219718.4",0.504],["NP_001095386.1","XP_015313851.2",0.692],["NP_001095386.1","XP_015313856.2",0.609],["NP_001095386.1","XP_024835118.1",0.583],["NP_001095386.1","XP_024835121.2",0.54],["NP_001095386.1","XP_024835123.2",0.663],["NP_001095386.1","XP_024835250.1",0.554],["XP_024835251.1","XP_015313851.2",0.524],["XP_024835251.1","XP_015313856.2",0.506],["XP_024835251.1","XP_024835123.2",0.5],["XP_024835251.1","NP_001095817.1",0.502],["XP_015313851.2","XP_002695390.2",0.681],["XP_015313851.2","XP_002695413.3",0.557],["XP_015313851.2","XP_002695418.2",0.582],["XP_015313851.2","XP_005219718.4",0.644],["XP_015313851.2","XP_005226082.2",0.687],["XP_015313851.2","XP_024835118.1",0.811],["XP_015313851.2","XP_024835121.2",0.671],["XP_015313851.2","XP_024835123.2",0.82],["XP_015313851.2","XP_024835250.1",0.656],["XP_015313851.2","XP_010813767.4",0.567],["XP_015313851.2","XP_015313856.2",0.713],["XP_015313851.2","XP_059733237.1",0.65],["XP_015313851.2","XP_059733313.1",0.864],["XP_015313851.2","XP_059733588.1",0.617],["XP_015313851.2","NP_001071487.1",0.667],["XP_015313851.2","NP_001095817.1",0.745],["XP_015313851.2","NP_001178971.1",0.703],["NP_001095817.1","XP_059733237.1",0.541],["NP_001095817.1","XP_059733313.1",0.649],["NP_001095817.1","XP_059733588.1",0.502],["NP_001095817.1","NP_001071487.1",0.541],["NP_001095817.1","NP_001096710.1",0.551],["NP_001095817.1","NP_001178971.1",0.619],["NP_001095817.1","XP_002695390.2",0.535],["NP_001095817.1","XP_002695413.3",0.573],["NP_001095817.1","XP_002695418.2",0.518],["NP_001095817.1","XP_010813767.4",0.538],["NP_001095817.1","XP_015313856.2",0.584],["NP_001095817.1","XP_024835118.1",0.524],["NP_001095817.1","XP_024835123.2",0.643],["NP_001095817.1","XP_024835250.1",0.568],["XP_005226082.2","XP_002695390.2",0.518],["XP_005226082.2","XP_002695418.2",0.58],["XP_005226082.2","XP_024835118.1",0.561],["XP_005226082.2","XP_024835123.2",0.684],["XP_005226082.2","XP_024835250.1",0.632],["XP_005226082.2","XP_059733588.1",0.583],["XP_005226082.2","NP_001071487.1",0.642],["XP_005226082.2","NP_001178971.1",0.564],["XP_005219718.4","XP_024835121.2",0.528],["XP_005219718.4","XP_024835123.2",0.519],["XP_005219718.4","XP_024835250.1",0.628],["XP_005219718.4","XP_059733237.1",0.639],["XP_005219718.4","XP_059733588.1",0.519],["XP_005219718.4","NP_001071487.1",0.535],["XP_024835250.1","XP_002695390.2",0.515],["XP_024835250.1","XP_002695413.3",0.524],["XP_024835250.1","XP_010813767.4",0.562],["XP_024835250.1","XP_015313856.2",0.643],["XP_024835250.1","XP_024835118.1",0.609],["XP_024835250.1","XP_024835121.2",0.616],["XP_024835250.1","XP_024835123.2",0.716],["XP_024835250.1","XP_059733237.1",0.512],["XP_024835250.1","XP_059733313.1",0.52],["XP_024835250.1","XP_059733588.1",0.511],["XP_024835250.1","NP_001071487.1",0.536],["XP_024835250.1","NP_001178971.1",0.524],["XP_002695390.2","XP_002695413.3",0.552],["XP_002695390.2","XP_002695418.2",0.575],["XP_002695390.2","XP_024835121.2",0.512],["XP_002695390.2","XP_024835123.2",0.642],["XP_002695390.2","XP_059733313.1",0.53],["XP_002695390.2","XP_059733588.1",0.532],["XP_002695390.2","NP_001071487.1",0.648],["XP_002695390.2","NP_001178971.1",0.601],["XP_002695418.2","XP_024835121.2",0.512],["XP_002695418.2","XP_024835123.2",0.641],["XP_002695418.2","NP_001071487.1",0.536],["XP_002695418.2","NP_001096710.1",0.649],["XP_024835121.2","XP_002695413.3",0.502],["XP_024835121.2","XP_024835118.1",0.537],["XP_024835121.2","XP_024835123.2",0.639],["XP_024835121.2","XP_059733237.1",0.514],["XP_024835121.2","NP_001071487.1",0.57],["NP_001071487.1","NP_001178971.1",0.508],["NP_001071487.1","XP_002695413.3",0.626],["NP_001071487.1","XP_015313856.2",0.522],["NP_001071487.1","XP_024835123.2",0.533],["NP_001071487.1","XP_059733237.1",0.607],["NP_001071487.1","XP_059733588.1",0.543],["XP_015313856.2","XP_002695413.3",0.608],["XP_015313856.2","XP_024835118.1",0.544],["XP_015313856.2","XP_024835123.2",0.663],["XP_015313856.2","XP_059733237.1",0.54],["XP_015313856.2","XP_059733313.1",0.519],["XP_015313856.2","XP_059733588.1",0.531],["NP_001096710.1","XP_024835123.2",0.523],["XP_059733313.1","XP_002695413.3",0.521],["XP_059733313.1","XP_024835118.1",0.564],["XP_059733313.1","XP_024835123.2",0.661],["XP_059733313.1","XP_059733237.1",0.55],["XP_010813767.4","XP_002695413.3",0.539],["XP_010813767.4","XP_024835123.2",0.653],["XP_024835118.1","XP_059733237.1",0.561],["XP_002695413.3","XP_024835123.2",0.539],["XP_002695413.3","NP_001178971.1",0.603],["NP_001178971.1","XP_024835123.2",0.632],["XP_059733237.1","XP_024835123.2",0.609],["XP_059733237.1","XP_059733588.1",0.526],["XP_059733588.1","XP_024835123.2",0.734]],"all_go_terms":{"GO:0006867":2,"GO:1990818":2,"GO:0090517":2,"GO:0089707":2,"GO:0051365":2,"GO:0090516":2,"GO:0090513":2,"GO:0061402":2,"GO:0048829":2,"GO:0090452":2,"GO:1901481":2,"GO:0090515":2,"GO:0015808":2,"GO:0090518":2,"GO:0089708":2,"GO:1901482":2,"GO:0015824":2,"GO:0090514":2,"GO:2000487":2,"GO:0098713":25,"GO:0006884":25,"GO:0006527":25,"GO:0071477":25,"GO:1902269":25,"GO:0044690":25,"GO:0002537":25,"GO:0097638":25,"GO:0006809":22,"GO:0042116":22,"GO:0070634":25,"GO:0097639":25,"GO:0097640":25,"GO:0043030":22,"GO:0035826":25,"GO:1902274":25,"GO:0015812":25,"GO:0042941":25,"GO:0010923":22,"GO:0042942":25},"recipe_readded":[]}