{"hash":"1443221033877937000","title":"Regulators of signaling and gene expression","description":"This cluster shows enrichment for signaling regulation (TNF signaling, NF-kappaB regulation) alongside core gene expression processes (DNA-templated transcription, translation). Additional terms touch on vesicle trafficking and genome maintenance, suggesting a broad regulatory role across multiple cellular processes rather than a single, cohesive pathway.","confidence":"Medium","size":17,"edges":81,"triangles":180,"max_degree":15,"top_function":null,"members":[{"accession":"NP_001094756.1","go_terms":["GO:0034453","GO:0030307"]},{"accession":"NP_001098826.1","go_terms":["GO:1902306","GO:0033209","GO:0032088","GO:0048227","GO:1902072","GO:2000009"]},{"accession":"XP_002689905.2","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"XP_005212557.1","go_terms":["GO:0000722","GO:0090342","GO:0008033","GO:0006351"]},{"accession":"XP_015317110.1","go_terms":[]},{"accession":"XP_015319709.2","go_terms":["GO:2001237","GO:0071222","GO:0033591","GO:0048147","GO:0009636","GO:0014003","GO:0071385","GO:0032869","GO:0043508","GO:0042178","GO:0007417","GO:0035726","GO:0032355","GO:1901687","GO:2000469","GO:0043651","GO:0070458","GO:0098869","GO:0070664","GO:2000429","GO:0043124","GO:0051771","GO:1904706","GO:0032720","GO:0019371","GO:0010804","GO:0006749","GO:0032930","GO:0014810","GO:0018916","GO:2000255","GO:0006289","GO:0045471","GO:0060316","GO:0031100","GO:0009072","GO:0002674","GO:0071364","GO:0043200","GO:0001516","GO:0070373","GO:0032691","GO:1905804","GO:0071638","GO:0035732","GO:0071460","GO:0071672","GO:0042594","GO:0010043","GO:0006808","GO:0042994","GO:0010044","GO:0009734","GO:0009635","GO:0002182","GO:0007608","GO:0055119","GO:0009407","GO:0043517","GO:0071285","GO:2000774","GO:0060510"]},{"accession":"XP_015325500.1","go_terms":["GO:0033314","GO:0006468","GO:0035038","GO:0006289","GO:0009790","GO:0008156","GO:0009411","GO:0044778","GO:0000722","GO:0071479","GO:0031573","GO:0000724","GO:0001932"]},{"accession":"XP_024857349.1","go_terms":["GO:0016120","GO:0006696","GO:0016117","GO:0045338"]},{"accession":"XP_059737211.1","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0090305","GO:0071897","GO:1900264","GO:0006261","GO:0007062"]},{"accession":"XP_059747028.1","go_terms":["GO:0015968","GO:0006415","GO:0006412","GO:0000027"]},{"accession":"NP_001013382.1","go_terms":["GO:0032026","GO:1903251","GO:0000320","GO:0007595","GO:0000082","GO:0019085","GO:0019086","GO:0060153","GO:0033197","GO:0051301","GO:0000411","GO:0010165","GO:0035186","GO:0000122","GO:0007129","GO:0000086","GO:0030857","GO:0071157","GO:0044828","GO:1990069","GO:0033601","GO:0044321","GO:2001165","GO:0046626","GO:1905866","GO:0060070","GO:0010673","GO:0033598","GO:0033327","GO:0060749","GO:0010389","GO:0030968","GO:0097421","GO:0045737","GO:0006351","GO:2000775","GO:0010696"]},{"accession":"NP_001030269.1","go_terms":["GO:0000462"]},{"accession":"NP_001035687.1","go_terms":["GO:1902306","GO:0033209","GO:0032088","GO:0048227","GO:1902072","GO:2000009"]},{"accession":"NP_001039830.1","go_terms":["GO:0007094","GO:0043248","GO:0006367"]},{"accession":"NP_001069588.1","go_terms":["GO:0048208","GO:0043473","GO:0006891","GO:0006888","GO:0043547","GO:0006914","GO:0042338","GO:1903232"]},{"accession":"NP_001091575.1","go_terms":["GO:0006620","GO:0051083"]},{"accession":"NP_001092428.1","go_terms":["GO:0060574","GO:0071480","GO:0000086","GO:0048146","GO:0034198","GO:0000082","GO:0033158","GO:0055123","GO:0048102","GO:2000379","GO:0007294","GO:0060065","GO:0060770","GO:0045035","GO:0071493","GO:0030308","GO:0031116","GO:1904706","GO:0045736","GO:0071236","GO:0030890","GO:0007488","GO:0006977","GO:0060669","GO:0032875","GO:0006978","GO:0071850","GO:0001890","GO:0042771","GO:0048839","GO:0071285","GO:0090399","GO:0090398","GO:0007096","GO:1902746"]}],"graph":[["NP_001039830.1","NP_001013382.1",0.65],["NP_001039830.1","NP_001030269.1",0.636],["NP_001039830.1","NP_001035687.1",0.665],["NP_001039830.1","NP_001092428.1",0.663],["NP_001039830.1","NP_001098826.1",0.653],["NP_001039830.1","XP_005212557.1",0.615],["NP_001039830.1","XP_015319709.2",0.532],["NP_001039830.1","XP_015325500.1",0.738],["NP_001039830.1","XP_059737211.1",0.783],["XP_015325500.1","XP_002689905.2",0.716],["XP_015325500.1","XP_005212557.1",0.738],["XP_015325500.1","XP_015317110.1",0.633],["XP_015325500.1","XP_015319709.2",0.72],["XP_015325500.1","XP_059737211.1",0.732],["XP_015325500.1","XP_024857349.1",0.597],["XP_015325500.1","NP_001013382.1",0.708],["XP_015325500.1","NP_001030269.1",0.628],["XP_015325500.1","NP_001035687.1",0.708],["XP_015325500.1","NP_001069588.1",0.79],["XP_015325500.1","NP_001091575.1",0.519],["XP_015325500.1","NP_001092428.1",0.771],["XP_015325500.1","NP_001094756.1",0.658],["XP_015325500.1","NP_001098826.1",0.737],["NP_001069588.1","NP_001013382.1",0.601],["NP_001069588.1","NP_001035687.1",0.631],["NP_001069588.1","NP_001092428.1",0.588],["NP_001069588.1","NP_001094756.1",0.524],["NP_001069588.1","NP_001098826.1",0.645],["NP_001069588.1","XP_002689905.2",0.68],["NP_001069588.1","XP_024857349.1",0.502],["NP_001035687.1","NP_001013382.1",0.65],["NP_001035687.1","NP_001092428.1",0.773],["NP_001035687.1","NP_001091575.1",0.665],["NP_001035687.1","NP_001098826.1",0.738],["NP_001035687.1","XP_015317110.1",0.662],["NP_001035687.1","XP_015319709.2",0.641],["NP_001035687.1","XP_002689905.2",0.676],["NP_001035687.1","XP_059737211.1",0.658],["XP_024857349.1","XP_002689905.2",0.503],["XP_024857349.1","NP_001013382.1",0.593],["XP_024857349.1","NP_001092428.1",0.64],["NP_001013382.1","NP_001091575.1",0.594],["NP_001013382.1","NP_001092428.1",0.787],["NP_001013382.1","NP_001094756.1",0.527],["NP_001013382.1","NP_001098826.1",0.69],["NP_001013382.1","XP_002689905.2",0.659],["NP_001013382.1","XP_005212557.1",0.604],["NP_001013382.1","XP_015317110.1",0.565],["NP_001013382.1","XP_059737211.1",0.66],["NP_001030269.1","NP_001091575.1",0.576],["NP_001030269.1","NP_001094756.1",0.547],["NP_001030269.1","NP_001098826.1",0.615],["NP_001030269.1","XP_015317110.1",0.546],["NP_001030269.1","XP_015319709.2",0.726],["NP_001030269.1","XP_059737211.1",0.582],["NP_001030269.1","XP_059747028.1",0.508],["NP_001098826.1","XP_059737211.1",0.686],["NP_001098826.1","NP_001091575.1",0.645],["NP_001098826.1","NP_001092428.1",0.845],["NP_001098826.1","NP_001094756.1",0.731],["NP_001098826.1","XP_015317110.1",0.736],["NP_001098826.1","XP_015319709.2",0.723],["NP_001098826.1","XP_005212557.1",0.615],["NP_001098826.1","XP_002689905.2",0.749],["XP_059737211.1","NP_001094756.1",0.69],["XP_059737211.1","XP_002689905.2",0.627],["XP_059737211.1","XP_005212557.1",0.531],["XP_059737211.1","XP_015317110.1",0.68],["XP_059737211.1","XP_015319709.2",0.6],["XP_059737211.1","NP_001092428.1",0.769],["NP_001091575.1","NP_001092428.1",0.607],["NP_001094756.1","NP_001092428.1",0.775],["NP_001094756.1","XP_002689905.2",0.618],["NP_001094756.1","XP_015317110.1",0.76],["XP_059747028.1","NP_001092428.1",0.633],["XP_002689905.2","XP_015317110.1",0.71],["XP_002689905.2","XP_015319709.2",0.644],["XP_002689905.2","XP_005212557.1",0.655],["NP_001092428.1","XP_005212557.1",0.638],["NP_001092428.1","XP_015317110.1",0.648],["NP_001092428.1","XP_015319709.2",0.624]],"all_go_terms":{"GO:0034453":1,"GO:0030307":1,"GO:2000009":2,"GO:0033209":2,"GO:0032088":2,"GO:0048227":2,"GO:1902072":2,"GO:1902306":2,"GO:0000185":1,"GO:0006412":2,"GO:0031118":1,"GO:0000470":1,"GO:1904571":1,"GO:0048025":1,"GO:0046330":1,"GO:2000623":1,"GO:0042254":1,"GO:0031120":1,"GO:0007338":1,"GO:0001682":1,"GO:1900745":1,"GO:0000492":1,"GO:0000722":2,"GO:0008033":1,"GO:0090342":1,"GO:0006351":2,"GO:0071364":1,"GO:0042994":1,"GO:0014810":1,"GO:0006808":1,"GO:0055119":1,"GO:0035732":1,"GO:0070664":1,"GO:0071285":2,"GO:0060316":1,"GO:0031100":1,"GO:0033591":1,"GO:1904706":2,"GO:0032720":1,"GO:0032355":1,"GO:1901687":1,"GO:0032930":1,"GO:0009635":1,"GO:0002182":1,"GO:0007608":1,"GO:2000774":1,"GO:0043517":1,"GO:0009407":1,"GO:0045471":1,"GO:0060510":1,"GO:0070373":1,"GO:1905804":1,"GO:0035726":1,"GO:2000429":1,"GO:0001516":1,"GO:0071672":1,"GO:0071222":1,"GO:0002674":1,"GO:2000255":1,"GO:0043124":1,"GO:0006289":2,"GO:0010804":1,"GO:0042594":1,"GO:0032869":1,"GO:2001237":1,"GO:0014003":1,"GO:0006749":1,"GO:0009072":1,"GO:0043651":1,"GO:0007417":1,"GO:0043508":1,"GO:0071638":1,"GO:0048147":1,"GO:0051771":1,"GO:0071385":1,"GO:2000469":1,"GO:0018916":1,"GO:0098869":1,"GO:0043200":1,"GO:0032691":1,"GO:0010043":1,"GO:0071460":1,"GO:0009734":1,"GO:0010044":1,"GO:0019371":1,"GO:0070458":1,"GO:0009636":1,"GO:0042178":1,"GO:0035038":1,"GO:0000724":1,"GO:0031573":1,"GO:0009790":1,"GO:0006468":1,"GO:0033314":2,"GO:0044778":1,"GO:0001932":1,"GO:0071479":1,"GO:0008156":1,"GO:0009411":1,"GO:0016117":1,"GO:0006696":1,"GO:0016120":1,"GO:0045338":1,"GO:0045053":1,"GO:0045041":1,"GO:0006272":1,"GO:0061166":1,"GO:0031117":1,"GO:0035494":1,"GO:0097352":1,"GO:0070682":1,"GO:0019079":1,"GO:0048219":1,"GO:2000158":1,"GO:0051301":2,"GO:1903007":1,"GO:0030433":1,"GO:0070407":1,"GO:0046034":1,"GO:0016485":1,"GO:0070676":1,"GO:0070389":1,"GO:1903862":1,"GO:1903715":1,"GO:0071897":1,"GO:0006261":1,"GO:0071218":1,"GO:0090305":1,"GO:0034214":1,"GO:0007062":1,"GO:0034551":1,"GO:1990171":1,"GO:2001171":1,"GO:0051013":1,"GO:0070370":1,"GO:0061641":1,"GO:0000733":1,"GO:0072389":1,"GO:0051260":1,"GO:1901800":1,"GO:0016562":1,"GO:0070842":1,"GO:0032968":1,"GO:0030968":2,"GO:0001319":1,"GO:0070651":1,"GO:0070414":1,"GO:0061738":1,"GO:1903724":1,"GO:0032979":1,"GO:0070914":1,"GO:0034599":1,"GO:0016558":1,"GO:0035617":1,"GO:0090296":1,"GO:0045899":1,"GO:0043335":1,"GO:0090261":1,"GO:0006260":1,"GO:0001824":1,"GO:0006888":2,"GO:0018279":1,"GO:0070987":1,"GO:0006406":1,"GO:1900264":1,"GO:0071712":1,"GO:0030420":1,"GO:0051131":1,"GO:0000027":1,"GO:0015968":1,"GO:0006415":1,"GO:0007595":1,"GO:0019086":1,"GO:0030857":1,"GO:0033598":1,"GO:0044321":1,"GO:1990069":1,"GO:1905866":1,"GO:0060070":1,"GO:0044828":1,"GO:0000411":1,"GO:0032026":1,"GO:0071157":1,"GO:0010165":1,"GO:0000122":1,"GO:2000775":1,"GO:1903251":1,"GO:0035186":1,"GO:0045737":1,"GO:0010389":1,"GO:0097421":1,"GO:0046626":1,"GO:0033327":1,"GO:0000320":1,"GO:0060749":1,"GO:0060153":1,"GO:0000086":2,"GO:0033197":1,"GO:0000082":2,"GO:0010673":1,"GO:0007129":1,"GO:0010696":1,"GO:0033601":1,"GO:2001165":1,"GO:0019085":1,"GO:0000462":1,"GO:0007094":1,"GO:0006367":1,"GO:0043248":1,"GO:0043547":1,"GO:0042338":1,"GO:0048208":1,"GO:0043473":1,"GO:1903232":1,"GO:0006914":1,"GO:0006891":1,"GO:0006620":1,"GO:0051083":1,"GO:0007488":1,"GO:0071480":1,"GO:0006978":1,"GO:0030308":1,"GO:0071236":1,"GO:1902746":1,"GO:0007294":1,"GO:0048102":1,"GO:0045035":1,"GO:0055123":1,"GO:2000379":1,"GO:0007096":1,"GO:0034198":1,"GO:0071493":1,"GO:0048839":1,"GO:0033158":1,"GO:0060770":1,"GO:0071850":1,"GO:0030890":1,"GO:0090398":1,"GO:0006977":1,"GO:0001890":1,"GO:0042771":1,"GO:0045736":1,"GO:0060065":1,"GO:0031116":1,"GO:0032875":1,"GO:0060669":1,"GO:0060574":1,"GO:0048146":1,"GO:0090399":1},"recipe_readded":[]}