{"hash":"1084383719531394320","title":"ER Trafficking and Steroid Biosynthesis","description":"This cluster is dominated by GO terms pointing to endoplasmic reticulum functions, especially retention in the ER lumen and ER-to-Golgi vesicle transport, plus ER-dependent peroxisome organization and steroid biosynthetic processes, suggesting a core role in ER-based protein processing and lipid metabolism. The remaining terms hint at related stress and signaling aspects (redox balance, apoptotic signaling) that can intersect ER function, while a few terms reflect broader developmental or mitochondrial processes that are less central but not mutually exclusive. Overall, the common theme centers on ER-associated protein handling and steroid/lipid biosynthesis.","confidence":"Medium","size":10,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_024840178.1","go_terms":["GO:2001238","GO:0018401","GO:0045454","GO:0006621"]},{"accession":"XP_005211112.2","go_terms":["GO:0070131","GO:0010082"]},{"accession":"XP_005227930.1","go_terms":[]},{"accession":"XP_015329678.1","go_terms":[]},{"accession":"NP_001068606.1","go_terms":["GO:0007413","GO:1990809","GO:0051292","GO:0060317","GO:0071788","GO:2000172","GO:0030517","GO:0071787","GO:0032581","GO:0021801","GO:0006694"]},{"accession":"NP_001039680.1","go_terms":["GO:0006888","GO:0042147","GO:0015031"]},{"accession":"NP_001039860.2","go_terms":["GO:0030719","GO:0006654","GO:0032049","GO:0010636","GO:0048017","GO:0016042"]},{"accession":"XP_010805473.1","go_terms":["GO:0032525","GO:0006888","GO:0001893","GO:0090161","GO:0006621","GO:0061357","GO:0048042","GO:0007311","GO:0048205","GO:0002121","GO:0035964","GO:0070863","GO:1902003"]},{"accession":"NP_001032716.1","go_terms":["GO:0010248","GO:1903278","GO:0086036","GO:2000649","GO:0036376","GO:0090662","GO:1990573"]},{"accession":"NP_892034.1","go_terms":["GO:0006656","GO:0006686"]}],"graph":[["XP_024840178.1","XP_005211112.2",0.642],["XP_024840178.1","NP_001039860.2",0.661]],"all_go_terms":{"GO:0018401":1,"GO:0045454":1,"GO:0006621":2,"GO:2001238":1,"GO:0010082":1,"GO:0070131":1,"GO:0060317":1,"GO:0032581":1,"GO:0006694":1,"GO:0007413":1,"GO:1990809":1,"GO:0051292":1,"GO:2000172":1,"GO:0021801":1,"GO:0030517":1,"GO:0071787":1,"GO:0071788":1,"GO:0042147":1,"GO:0015031":1,"GO:0006888":2,"GO:0032049":1,"GO:0030719":1,"GO:0016042":1,"GO:0006654":1,"GO:0010636":1,"GO:0048017":1,"GO:0061357":1,"GO:0035964":1,"GO:0070863":1,"GO:1902003":1,"GO:0002121":1,"GO:0001893":1,"GO:0032525":1,"GO:0007311":1,"GO:0048205":1,"GO:0090161":1,"GO:0048042":1,"GO:1990573":1,"GO:0036376":1,"GO:2000649":1,"GO:0086036":1,"GO:1903278":1,"GO:0010248":1,"GO:0090662":1,"GO:0006686":1,"GO:0006656":1},"recipe_readded":["NP_001422089.1","XP_010807566.1","XP_024854020.1","NP_001106789.1","XP_024835025.1","NP_001068746.1","NP_001039445.1","XP_005223097.1","NP_001030377.1","XP_024835507.1","XP_024844823.1","NP_001014930.1","NP_001091601.1","NP_001014941.1","XP_059733484.1","NP_001068620.1","XP_005214512.1","XP_002692488.1","NP_001030470.1","NP_001030465.1"]}