{"hash":"1835981993071748547","title":"Vacuolar trafficking and acidification","description":"This cluster is dominated by GO terms tied to the vacuole (protein targeting to vacuole, vacuole organization, vacuolar acidification) and proton/ion transport (proton transmembrane transport, proton motive force-driven ATP synthesis, sodium ion transport). These together suggest a role in vacuolar membrane function, acidification by proton pumps, and ion homeostasis, likely involving vacuolar targeting pathways and associated transport machinery (e.g., V-ATPase\u2013related processes). While a copper ion homeostasis term also appears, it can be related to vacuolar storage/handling of metals, reinforcing the membrane/ion-transport theme. Overall, the cluster reflects vacuolar targeting plus proton/ion transport activity. ","confidence":"High","size":6,"edges":5,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"XP_067728146.1","go_terms":["GO:0032042","GO:0070150","GO:0006450","GO:0006433","GO:0006427","GO:0070159","GO:0015966","GO:0001701","GO:0022904","GO:0070584","GO:0006412","GO:0071897","GO:0016260","GO:0070158","GO:0097056","GO:0006435","GO:0070143"]},{"accession":"XP_067718783.1","go_terms":["GO:0007033","GO:0006878","GO:0015991","GO:0006626","GO:0007035","GO:0006623","GO:0042777","GO:0006814"]},{"accession":"XP_067721211.1","go_terms":[]},{"accession":"XP_067723193.1","go_terms":[]},{"accession":"XP_067723592.1","go_terms":["GO:0007033","GO:0006878","GO:0015991","GO:0006626","GO:0007035","GO:0006623","GO:0042777","GO:0006814"]},{"accession":"XP_067724121.1","go_terms":[]}],"graph":[["XP_067728146.1","XP_067718783.1",0.767],["XP_067728146.1","XP_067721211.1",0.859],["XP_067728146.1","XP_067723193.1",0.857],["XP_067728146.1","XP_067723592.1",0.86],["XP_067728146.1","XP_067724121.1",0.704]],"all_go_terms":{"GO:0071897":1,"GO:0006450":1,"GO:0070150":1,"GO:0015966":1,"GO:0097056":1,"GO:0001701":1,"GO:0070158":1,"GO:0006435":1,"GO:0006433":1,"GO:0032042":1,"GO:0070159":1,"GO:0016260":1,"GO:0070143":1,"GO:0006412":1,"GO:0006427":1,"GO:0022904":1,"GO:0070584":1,"GO:0006623":2,"GO:0006814":2,"GO:0006626":2,"GO:0007033":2,"GO:0007035":2,"GO:0042777":2,"GO:0015991":2,"GO:0006878":2},"recipe_readded":[]}