{"hash":"314896023464427662","title":"RNA Polymerase II/III Transcription Initiation","description":"This cluster centers on transcription initiation and open complex formation at promoters, covering both RNA polymerase II and RNA polymerase III systems (including preinitiation complex assembly for Pol III and promoter initiation for Pol II/III). The convergence of terms like transcription initiation at Pol II/Pol III promoters and open complex formation strongly suggests a shared role in transcription initiation machinery, rather than a metabolic or signaling pathway. The lone outlier term (thrombocyte differentiation) is likely noise and does not alter the overall theme.","confidence":"High","size":7,"edges":5,"triangles":0,"max_degree":3,"top_function":null,"members":[{"accession":"XP_014143368.1","go_terms":[]},{"accession":"XP_014151560.1","go_terms":[]},{"accession":"XP_014153513.1","go_terms":["GO:0002574","GO:0001112","GO:0090074","GO:0070893","GO:0070898","GO:0006384","GO:0045945","GO:0051123","GO:0006355","GO:0001113","GO:0001174","GO:1904798","GO:0006351","GO:0006367","GO:0050434"]},{"accession":"XP_014144411.1","go_terms":["GO:0048611","GO:0007041","GO:1904810","GO:0090156","GO:0042147","GO:1904811","GO:0006896","GO:0090326","GO:0032456","GO:0010668"]},{"accession":"XP_014146064.1","go_terms":[]},{"accession":"XP_014150166.1","go_terms":[]},{"accession":"XP_014156422.1","go_terms":[]}],"graph":[["XP_014143368.1","XP_014151560.1",0.506],["XP_014143368.1","XP_014153513.1",0.752],["XP_014144411.1","XP_014146064.1",0.626],["XP_014144411.1","XP_014150166.1",0.819],["XP_014144411.1","XP_014156422.1",0.539]],"all_go_terms":{"GO:0006367":1,"GO:0002574":1,"GO:0070898":1,"GO:0006384":1,"GO:1904798":1,"GO:0045945":1,"GO:0001174":1,"GO:0001113":1,"GO:0001112":1,"GO:0090074":1,"GO:0006355":1,"GO:0051123":1,"GO:0070893":1,"GO:0006351":1,"GO:0050434":1,"GO:0007041":1,"GO:0042147":1,"GO:0006896":1,"GO:0032456":1,"GO:1904811":1,"GO:0010668":1,"GO:0090156":1,"GO:1904810":1,"GO:0048611":1,"GO:0090326":1},"recipe_readded":[]}