{"hash":"2220417440541943731","title":"Folate metabolism and thymidylate synthesis","description":"Proteins in this cluster cluster around folate- and one-carbon metabolism, with GO terms for tetrahydrofolate and tetrahydrobiopterin biosynthesis, dTMP/thymidylate biosynthesis, and related drug responses (methotrexate, antibiotics). This suggests a cohesive theme of folate-driven nucleotide synthesis and associated regulatory or stress responses.","confidence":"High","size":3,"edges":3,"triangles":1,"max_degree":2,"top_function":null,"members":[{"accession":"XP_014161309.1","go_terms":["GO:0006730","GO:0000083","GO:0051000","GO:0046655","GO:0046654","GO:0006545","GO:0032259","GO:0006729","GO:0031103","GO:0046105","GO:0055114","GO:2000121","GO:0006231","GO:0031427","GO:0046452","GO:0046677"]},{"accession":"XP_014150816.1","go_terms":["GO:0071456","GO:0031639","GO:0030855","GO:0006096","GO:0016525"]},{"accession":"XP_014151298.1","go_terms":["GO:0019619","GO:0060702"]}],"graph":[["XP_014161309.1","XP_014150816.1",0.958],["XP_014161309.1","XP_014151298.1",0.983],["XP_014151298.1","XP_014150816.1",0.989]],"all_go_terms":{"GO:0046677":1,"GO:0046105":1,"GO:0055114":1,"GO:0046655":1,"GO:0051000":1,"GO:0006729":1,"GO:0006231":1,"GO:0000083":1,"GO:0031427":1,"GO:0046654":1,"GO:0006545":1,"GO:0006730":1,"GO:2000121":1,"GO:0031103":1,"GO:0032259":1,"GO:0046452":1,"GO:0030855":1,"GO:0006096":1,"GO:0071456":1,"GO:0031639":1,"GO:0016525":1,"GO:0019619":1,"GO:0060702":1},"recipe_readded":[]}