{"hash":"1663541583185578557","title":"Translation machinery and mRNA turnover","description":"Based on the dominant GO terms, the cluster is enriched for processes related to protein synthesis (translation, translational initiation/termination, cytoplasmic translation) and ribosome dynamics (ribosome disassembly). The presence of deadenylation-dependent decay indicates mRNA turnover is linked to the translational machinery. A minority of terms (response to antibiotic, siRNA-mediated chromatin regulation) may reflect ancillary functions, but the strongest signal ties to ribosome-based translation and mRNA decay.","confidence":"High","size":16,"edges":36,"triangles":28,"max_degree":14,"top_function":null,"members":[{"accession":"XP_014158368.1","go_terms":["GO:0006654","GO:0036089","GO:0051044","GO:0031139","GO:1990126","GO:0006907","GO:0008333","GO:0060348","GO:0061512","GO:1990502","GO:1990854","GO:0071800","GO:0000902","GO:0071539","GO:0010252","GO:1903595","GO:2000769","GO:0034498","GO:0032258","GO:0034499","GO:2000642","GO:1904179","GO:0048310","GO:0000278","GO:0060378","GO:1904888","GO:0001654","GO:0000281","GO:0072673","GO:0048015","GO:0045022","GO:0043547","GO:0022617","GO:0002051","GO:0097320","GO:0070676","GO:0032120","GO:0032005","GO:0032534"]},{"accession":"XP_014159194.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"XP_014146364.1","go_terms":["GO:0071232","GO:0045900","GO:0071264","GO:0000056","GO:0006824","GO:0030253","GO:0030153","GO:0017004","GO:0031460","GO:0010949","GO:0046677","GO:0009432","GO:0099040","GO:0046618","GO:0042883","GO:0015734","GO:0008643","GO:0042760","GO:0015910","GO:1900753","GO:0015777","GO:0006855","GO:0019885","GO:0099133","GO:0090374","GO:0046689","GO:0060702","GO:0006289","GO:0015821","GO:0045332","GO:0015803","GO:0000770","GO:0015888","GO:0035461","GO:0043213","GO:0045796","GO:0003333","GO:0043215","GO:0001407","GO:0042953","GO:0072089","GO:0015689","GO:0015886"]},{"accession":"XP_014146701.1","go_terms":[]},{"accession":"XP_014153630.1","go_terms":[]},{"accession":"XP_014154499.1","go_terms":["GO:0000463","GO:0006412"]},{"accession":"XP_014155041.1","go_terms":[]},{"accession":"XP_014156165.1","go_terms":[]},{"accession":"XP_014159165.1","go_terms":[]},{"accession":"XP_014160222.1","go_terms":["GO:0000747","GO:0042274","GO:0000055","GO:0042254","GO:1901001","GO:0002181","GO:1903833","GO:0051301","GO:0006400","GO:0090529","GO:0007049","GO:0070125","GO:0045901","GO:0017183","GO:0014009","GO:1990145","GO:0002244","GO:1902802","GO:1990416","GO:0035914","GO:2000767","GO:0032790","GO:0032543","GO:0003009","GO:0000288","GO:0045903","GO:0002184","GO:0001514","GO:0046677","GO:0006413","GO:0006412","GO:0006449","GO:0000388","GO:0000244","GO:0000349","GO:0006415"]},{"accession":"XP_014154232.1","go_terms":["GO:0046632","GO:0002181"]},{"accession":"XP_014157186.1","go_terms":["GO:0032436","GO:0001701","GO:0048142","GO:0043248","GO:0007127","GO:0075525","GO:0000122","GO:0008283","GO:0002188","GO:0035914","GO:1902416","GO:0071033","GO:0006283","GO:0030182","GO:0070196","GO:0000338","GO:0075522","GO:0006446","GO:0034260","GO:0070321","GO:0010972","GO:0048863","GO:0001732","GO:0001731","GO:0048140","GO:0036099","GO:0090054","GO:0090052","GO:0000715","GO:0000973","GO:0006511"]},{"accession":"XP_014161135.1","go_terms":["GO:0001732","GO:0006413","GO:0006412"]},{"accession":"XP_014160768.1","go_terms":["GO:0033119","GO:0000462","GO:0006417","GO:0006378","GO:0006412"]},{"accession":"XP_014153891.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"XP_014160594.1","go_terms":["GO:0046898","GO:0046677","GO:0006412"]}],"graph":[["XP_014153891.1","XP_014146364.1",0.842],["XP_014153891.1","XP_014155041.1",0.855],["XP_014153891.1","XP_014154499.1",0.661],["XP_014153891.1","XP_014156165.1",0.853],["XP_014153891.1","XP_014157186.1",0.731],["XP_014153891.1","XP_014159194.1",0.875],["XP_014153891.1","XP_014160768.1",0.958],["XP_014153891.1","XP_014161135.1",0.621],["XP_014153630.1","XP_014146364.1",0.561],["XP_014153630.1","XP_014160768.1",0.694],["XP_014156165.1","XP_014159194.1",0.517],["XP_014160594.1","XP_014158368.1",0.885],["XP_014160594.1","XP_014159194.1",0.903],["XP_014160222.1","XP_014159194.1",0.849],["XP_014154232.1","XP_014159194.1",0.934],["XP_014154232.1","XP_014158368.1",0.728],["XP_014159194.1","XP_014146364.1",0.97],["XP_014159194.1","XP_014146701.1",0.819],["XP_014159194.1","XP_014154499.1",0.913],["XP_014159194.1","XP_014155041.1",0.954],["XP_014159194.1","XP_014157186.1",0.896],["XP_014159194.1","XP_014158368.1",0.8],["XP_014159194.1","XP_014160768.1",0.957],["XP_014159194.1","XP_014161135.1",0.764],["XP_014159194.1","XP_014159165.1",0.941],["XP_014146701.1","XP_014146364.1",0.58],["XP_014146701.1","XP_014154499.1",0.732],["XP_014146701.1","XP_014155041.1",0.961],["XP_014146701.1","XP_014160768.1",0.966],["XP_014160768.1","XP_014155041.1",0.906],["XP_014160768.1","XP_014158368.1",0.666],["XP_014160768.1","XP_014161135.1",0.517],["XP_014154499.1","XP_014146364.1",0.588],["XP_014154499.1","XP_014158368.1",0.623],["XP_014155041.1","XP_014146364.1",0.643],["XP_014155041.1","XP_014157186.1",0.667]],"all_go_terms":{"GO:0051044":1,"GO:0032120":1,"GO:2000769":1,"GO:0034498":1,"GO:0032258":1,"GO:0048310":1,"GO:1904888":1,"GO:1990126":1,"GO:0031139":1,"GO:0097320":1,"GO:0000278":1,"GO:0006907":1,"GO:0043547":1,"GO:0022617":1,"GO:1904179":1,"GO:0032534":1,"GO:0000281":1,"GO:1990502":1,"GO:0071800":1,"GO:0048015":1,"GO:1903595":1,"GO:0002051":1,"GO:0060348":1,"GO:0032005":1,"GO:0060378":1,"GO:0010252":1,"GO:0061512":1,"GO:0006654":1,"GO:0072673":1,"GO:0034499":1,"GO:0070676":1,"GO:0008333":1,"GO:0036089":1,"GO:0071539":1,"GO:0001654":1,"GO:0000902":1,"GO:1990854":1,"GO:0045022":1,"GO:2000642":1,"GO:0006413":3,"GO:0006449":2,"GO:2000767":2,"GO:0000288":2,"GO:1902802":2,"GO:0032790":2,"GO:0006415":2,"GO:0002184":2,"GO:0070125":2,"GO:0014009":2,"GO:0045901":2,"GO:0046677":4,"GO:0006412":7,"GO:0001514":2,"GO:0045903":2,"GO:0019079":1,"GO:0001172":1,"GO:0008643":1,"GO:0006824":1,"GO:0015777":1,"GO:0045332":1,"GO:0099040":1,"GO:0015734":1,"GO:0045796":1,"GO:0099133":1,"GO:0015821":1,"GO:0042760":1,"GO:0071264":1,"GO:0000056":1,"GO:1900753":1,"GO:0060702":1,"GO:0003333":1,"GO:0046618":1,"GO:0071232":1,"GO:0042953":1,"GO:0015910":1,"GO:0030153":1,"GO:0010949":1,"GO:0043215":1,"GO:0015886":1,"GO:0090374":1,"GO:0001407":1,"GO:0015689":1,"GO:0031460":1,"GO:0006855":1,"GO:0030253":1,"GO:0009432":1,"GO:0000770":1,"GO:0035461":1,"GO:0043213":1,"GO:0042883":1,"GO:0072089":1,"GO:0015803":1,"GO:0006289":1,"GO:0046689":1,"GO:0015888":1,"GO:0017004":1,"GO:0019885":1,"GO:0045900":1,"GO:0000463":1,"GO:0035914":2,"GO:0002181":2,"GO:0042254":2,"GO:0090529":1,"GO:1901001":1,"GO:0000244":1,"GO:0051301":1,"GO:0003009":1,"GO:1903833":1,"GO:0007049":1,"GO:0000055":1,"GO:0006400":1,"GO:0000747":1,"GO:0017183":1,"GO:0042274":1,"GO:0000388":1,"GO:1990145":1,"GO:0032543":1,"GO:0000349":1,"GO:0002244":1,"GO:1990416":1,"GO:0046632":1,"GO:0000338":1,"GO:0006511":1,"GO:0000715":1,"GO:0006283":1,"GO:0090052":1,"GO:1902416":1,"GO:0090054":1,"GO:0001732":2,"GO:0000973":1,"GO:0075525":1,"GO:0001701":1,"GO:0071033":1,"GO:0070321":1,"GO:0048140":1,"GO:0070196":1,"GO:0048142":1,"GO:0002188":1,"GO:0000122":1,"GO:0006446":1,"GO:0034260":1,"GO:0043248":1,"GO:0036099":1,"GO:0007127":1,"GO:0075522":1,"GO:0010972":1,"GO:0030182":1,"GO:0008283":1,"GO:0048863":1,"GO:0001731":1,"GO:0032436":1,"GO:0006378":1,"GO:0000462":1,"GO:0033119":1,"GO:0006417":1,"GO:1900745":1,"GO:0000470":1,"GO:0007338":1,"GO:2000623":1,"GO:0046330":1,"GO:0000492":1,"GO:0031120":1,"GO:0001682":1,"GO:0031118":1,"GO:1904571":1,"GO:0048025":1,"GO:0000185":1,"GO:0046898":1},"recipe_readded":[]}