{"hash":"1421661213833277321","title":"Ubiquitin-Dependent TNF/NF-\u03baB Signaling","description":"The terms cluster around ubiquitination (protein ubiquitination, K6-linked ubiquitination, ubiquitin-dependent protein catabolic process) and inflammatory signaling (TNF-mediated signaling, I-kappaB phosphorylation, regulation of the JNK cascade). While there are a couple of histone modification and V(D)J recombination mentions, the dominant theme is ubiquitin-mediated regulation of inflammatory pathways and protein turnover. This suggests a function in ubiquitin-dependent control of TNF and NF-\u03baB/JNK signaling.","confidence":"High","size":8,"edges":9,"triangles":2,"max_degree":6,"top_function":null,"members":[{"accession":"XP_013398510.1","go_terms":["GO:0033151","GO:0033209","GO:0009048","GO:0036205","GO:0046328","GO:2000620","GO:0042981","GO:0007250","GO:0070512","GO:0085020","GO:0042787","GO:0070535","GO:1903265","GO:1903762","GO:1903721","GO:1901253","GO:0090073","GO:0051865"]},{"accession":"XP_013404864.1","go_terms":[]},{"accession":"XP_013389045.1","go_terms":[]},{"accession":"XP_013381804.2","go_terms":[]},{"accession":"XP_013398198.1","go_terms":["GO:0045792","GO:0032007","GO:0048011","GO:0038202"]},{"accession":"XP_013401198.1","go_terms":[]},{"accession":"XP_013406187.1","go_terms":[]},{"accession":"XP_013397560.1","go_terms":[]}],"graph":[["XP_013398198.1","XP_013404864.1",0.564],["XP_013398198.1","XP_013398510.1",0.779],["XP_013398510.1","XP_013404864.1",0.669],["XP_013398510.1","XP_013406187.1",0.579],["XP_013398510.1","XP_013381804.2",0.533],["XP_013398510.1","XP_013389045.1",0.657],["XP_013398510.1","XP_013397560.1",0.733],["XP_013397560.1","XP_013389045.1",0.794],["XP_013404864.1","XP_013401198.1",0.674]],"all_go_terms":{"GO:0033151":1,"GO:1903721":1,"GO:0036205":1,"GO:0070512":1,"GO:0046328":1,"GO:2000620":1,"GO:0051865":1,"GO:0033209":1,"GO:0085020":1,"GO:0042787":1,"GO:1901253":1,"GO:0090073":1,"GO:0007250":1,"GO:1903265":1,"GO:0042981":1,"GO:1903762":1,"GO:0070535":1,"GO:0009048":1,"GO:0048011":1,"GO:0032007":1,"GO:0045792":1,"GO:0038202":1},"recipe_readded":[]}