{"hash":"935785570641545070","title":"Golgi-ER trafficking and SNARE complex assembly","description":"This cluster is dominated by GO terms for Golgi organization and ER-to-Golgi vesicle transport, vesicle fusion with the Golgi, and SNARE complex assembly, complemented by terms on exocytic insertion of receptors and synaptic potentiation. This points to a cohesive function in secretory pathway trafficking and SNARE-mediated membrane fusion, including neuronal receptor trafficking at synapses. A vacuole-targeting term is more general vesicle transport and does not contradict the main theme. Overall, the common thread is Golgi-ER vesicle trafficking governed by SNAREs.","confidence":"High","size":27,"edges":4,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_009494930.1","go_terms":["GO:0001302","GO:0071291","GO:0010447","GO:0003069","GO:0048773","GO:0019430","GO:0001320","GO:0055114"]},{"accession":"XP_009498024.1","go_terms":["GO:0031204","GO:0006620"]},{"accession":"XP_009493847.1","go_terms":[]},{"accession":"XP_009494132.1","go_terms":["GO:0045047","GO:0006465"]},{"accession":"XP_009497699.1","go_terms":["GO:2000185","GO:0006817","GO:0051604"]},{"accession":"XP_009492235.1","go_terms":[]},{"accession":"XP_009495259.1","go_terms":["GO:0015937","GO:0046939","GO:0009435","GO:0046940"]},{"accession":"XP_009495207.1","go_terms":["GO:0051024","GO:0061669","GO:0010807","GO:1903358","GO:1903575","GO:0007340","GO:1904050","GO:0010701","GO:2000010","GO:0090161","GO:0097352","GO:1903422","GO:0032258","GO:0098967","GO:1902685","GO:2000463","GO:1903078","GO:0016081","GO:0010811","GO:0006888","GO:0045022","GO:0034498","GO:0001916","GO:0006891","GO:0006896","GO:0060291","GO:0051469","GO:0043311","GO:0031629","GO:0048280","GO:0097111","GO:0033194","GO:0006675","GO:0090166","GO:0035493"]},{"accession":"XP_009493245.1","go_terms":[]},{"accession":"XP_009494790.1","go_terms":[]},{"accession":"XP_009497239.1","go_terms":["GO:0006903","GO:0034197","GO:0043308","GO:0006888","GO:0043320","GO:1990668","GO:0042144","GO:0042147","GO:0050775","GO:0006891","GO:0006890","GO:0043312","GO:0048280","GO:1903595","GO:0015031","GO:0035493","GO:1900483","GO:0032869","GO:0090161","GO:0043001","GO:0098967","GO:0016240","GO:0090316","GO:0001921","GO:0060291","GO:0016079","GO:1902259","GO:0043134","GO:0070254"]},{"accession":"XP_009496577.1","go_terms":[]},{"accession":"XP_009495768.1","go_terms":[]},{"accession":"XP_009492904.1","go_terms":["GO:0045892","GO:0019363"]},{"accession":"XP_009492302.1","go_terms":[]},{"accession":"XP_009492319.1","go_terms":["GO:0032525","GO:0006888","GO:0001893","GO:0090161","GO:0006621","GO:0061357","GO:0048042","GO:0007311","GO:0048205","GO:0002121","GO:0035964","GO:0070863","GO:1902003"]},{"accession":"XP_009492738.1","go_terms":[]},{"accession":"XP_009493431.1","go_terms":["GO:0033299","GO:0006622","GO:0034497","GO:0032258","GO:0030242","GO:0006810"]},{"accession":"XP_009493497.1","go_terms":[]},{"accession":"XP_009493915.1","go_terms":["GO:0022900"]},{"accession":"XP_009493980.1","go_terms":["GO:0070072","GO:0007035"]},{"accession":"XP_009494422.1","go_terms":[]},{"accession":"XP_009494783.1","go_terms":[]},{"accession":"XP_009495417.1","go_terms":[]},{"accession":"XP_009496427.1","go_terms":[]},{"accession":"XP_009497464.1","go_terms":["GO:0006855","GO:0036010","GO:0010570","GO:0045332","GO:0070863","GO:0044088"]},{"accession":"XP_009497493.1","go_terms":["GO:0030323","GO:0060437","GO:0090263","GO:1905609","GO:0060670","GO:1990874","GO:0030282","GO:0001649","GO:0042489","GO:2000052","GO:0002001","GO:0060441","GO:0002040","GO:0033336","GO:0033337","GO:0033335","GO:0033339","GO:0035115","GO:0035116","GO:0002090","GO:0042089","GO:0071542","GO:0035878","GO:0001974","GO:0060535","GO:0033340"]}],"graph":[["XP_009492904.1","XP_009497239.1",0.873],["XP_009492904.1","XP_009495207.1",0.701],["XP_009497239.1","XP_009495259.1",0.548],["XP_009495259.1","XP_009495207.1",0.615]],"all_go_terms":{"GO:0001320":1,"GO:0003069":1,"GO:0001302":1,"GO:0019430":1,"GO:0010447":1,"GO:0071291":1,"GO:0055114":1,"GO:0048773":1,"GO:0006620":1,"GO:0031204":1,"GO:0006465":1,"GO:0045047":1,"GO:0006817":1,"GO:2000185":1,"GO:0051604":1,"GO:0009435":1,"GO:0046940":1,"GO:0046939":1,"GO:0015937":1,"GO:2000010":1,"GO:0006675":1,"GO:2000463":1,"GO:0007340":1,"GO:0031629":1,"GO:0033194":1,"GO:0034498":1,"GO:0090161":3,"GO:0010811":1,"GO:0061669":1,"GO:0051024":1,"GO:1902685":1,"GO:0048280":2,"GO:0006891":2,"GO:0097111":1,"GO:0098967":2,"GO:0035493":2,"GO:1903358":1,"GO:0001916":1,"GO:1903422":1,"GO:0097352":1,"GO:1903078":1,"GO:0006888":3,"GO:0051469":1,"GO:0043311":1,"GO:1904050":1,"GO:0032258":2,"GO:0010807":1,"GO:1903575":1,"GO:0045022":1,"GO:0090166":1,"GO:0010701":1,"GO:0016081":1,"GO:0060291":2,"GO:0006896":1,"GO:0001921":1,"GO:0070254":1,"GO:0006890":1,"GO:1903595":1,"GO:1902259":1,"GO:0090316":1,"GO:0016079":1,"GO:0042144":1,"GO:0006903":1,"GO:0043320":1,"GO:1900483":1,"GO:0043308":1,"GO:0043134":1,"GO:0016240":1,"GO:0043001":1,"GO:0050775":1,"GO:0032869":1,"GO:0042147":1,"GO:0043312":1,"GO:1990668":1,"GO:0015031":1,"GO:0034197":1,"GO:0045892":1,"GO:0019363":1,"GO:0048042":1,"GO:0070863":2,"GO:0006621":1,"GO:0048205":1,"GO:0035964":1,"GO:0001893":1,"GO:0007311":1,"GO:1902003":1,"GO:0061357":1,"GO:0002121":1,"GO:0032525":1,"GO:0030242":1,"GO:0034497":1,"GO:0006810":1,"GO:0006622":1,"GO:0033299":1,"GO:0022900":1,"GO:0007035":1,"GO:0070072":1,"GO:0044088":1,"GO:0006855":1,"GO:0045332":1,"GO:0010570":1,"GO:0036010":1,"GO:0033339":1,"GO:0002001":1,"GO:0030323":1,"GO:0001649":1,"GO:0001974":1,"GO:0042089":1,"GO:0002040":1,"GO:0060437":1,"GO:0002090":1,"GO:0042489":1,"GO:1905609":1,"GO:0033335":1,"GO:0033337":1,"GO:0071542":1,"GO:2000052":1,"GO:0060535":1,"GO:0033336":1,"GO:0035116":1,"GO:1990874":1,"GO:0030282":1,"GO:0035115":1,"GO:0033340":1,"GO:0035878":1,"GO:0060670":1,"GO:0090263":1,"GO:0060441":1},"recipe_readded":["XP_009496493.1","XP_009496589.1","XP_009492954.1","XP_009494321.1","XP_009496111.1","XP_009498411.1","XP_009496026.1","XP_009494969.1","XP_009493512.1","XP_009494299.1","XP_009496194.1","XP_009495506.1","XP_009492922.1","XP_009497426.1","XP_009498343.1","XP_009493867.1","XP_009495665.1","XP_009492965.1","XP_009496029.1","XP_009495324.1"]}