{"hash":"990545265540571951","title":"Ubiquitin-mediated protein degradation","description":"GO terms predominantly point to ubiquitination and degradation pathways, including polyubiquitination, ubiquitin-dependent protein catabolic process, and ERAD-related pathways, as well as degradation of receptors (Wnt). Additional terms touching cell cycle and signaling regulation fit with proteostasis-driven control of growth and signaling. Overall, the cluster appears to group proteins involved in ubiquitin-dependent turnover and turnover-regulated signaling. ","confidence":"High","size":8,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_005786549.1","go_terms":["GO:0038018","GO:0016558","GO:0030433","GO:0060816","GO:0051865","GO:0042787","GO:0046621","GO:1900095","GO:0070936","GO:0060544","GO:0000122","GO:0034121","GO:0043066","GO:0000209","GO:0071157"]},{"accession":"XP_005766817.1","go_terms":["GO:0032781","GO:0016973","GO:0051096"]},{"accession":"XP_005769788.1","go_terms":["GO:0007175","GO:1904876","GO:1902570","GO:0032211","GO:0000381","GO:0051096","GO:0000390","GO:0000494","GO:0097309","GO:1904751","GO:0006370","GO:1904744","GO:0008380"]},{"accession":"XP_005786512.1","go_terms":[]},{"accession":"XP_005760671.1","go_terms":[]},{"accession":"XP_005771843.1","go_terms":[]},{"accession":"XP_005792454.1","go_terms":[]},{"accession":"XP_005772030.1","go_terms":["GO:0010197","GO:0006267","GO:0042254","GO:0000027"]}],"graph":[],"all_go_terms":{"GO:0071157":1,"GO:0051865":1,"GO:0042787":1,"GO:0046621":1,"GO:0000209":1,"GO:0038018":1,"GO:1900095":1,"GO:0034121":1,"GO:0030433":1,"GO:0000122":1,"GO:0016558":1,"GO:0043066":1,"GO:0060544":1,"GO:0070936":1,"GO:0060816":1,"GO:0051096":2,"GO:0032781":1,"GO:0016973":1,"GO:1904751":1,"GO:1902570":1,"GO:0000390":1,"GO:0000381":1,"GO:1904876":1,"GO:0097309":1,"GO:0006370":1,"GO:0000494":1,"GO:1904744":1,"GO:0008380":1,"GO:0032211":1,"GO:0007175":1,"GO:0010197":1,"GO:0000027":1,"GO:0042254":1,"GO:0006267":1},"recipe_readded":["XP_005779479.1","XP_005787315.1","XP_005787393.1","XP_005786780.1","XP_005784068.1","XP_005783867.1","XP_005794405.1","XP_005765631.1","XP_005793915.1","XP_005785293.1","XP_005760499.1","XP_005756881.1","XP_005777679.1","XP_005769278.1","XP_005774732.1","XP_005756770.1","XP_005761599.1","XP_005774821.1","XP_005779400.1","XP_005776704.1"]}