{"hash":"2189528466969813073","title":"Ubiquitin-Proteasome Regulation","description":"The three proteins appear linked by terms centered on ubiquitination and proteasomal degradation (SCF-dependent ubiquitin-protein catabolic process; protein deubiquitination) and by signaling pathways commonly modulated by ubiquitination, such as NF-kappaB and canonical Wnt signaling. Additional terms touching inflammatory and antiviral responses fit downstream effects of ubiquitin-regulated signaling. This suggests a common theme around proteostasis and signaling regulation via the ubiquitin-proteasome system, despite the presence of some broad/obsolete GO terms. Confidence: Medium","confidence":"","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_005765260.1","go_terms":["GO:0019878","GO:0055114"]},{"accession":"XP_005790223.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0010043","GO:0009651","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0043488","GO:0006521","GO:0002479","GO:0046686","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0060071","GO:0010972","GO:0010950","GO:0002862","GO:0038095","GO:0010363","GO:0016579","GO:0010499","GO:0016032"]},{"accession":"XP_005762226.1","go_terms":["GO:0006777","GO:0016236","GO:0034727","GO:1990592","GO:0021764","GO:0002143","GO:0032447","GO:0045116","GO:0018192","GO:0006501","GO:0032258","GO:0009229","GO:0009228","GO:0050832","GO:2000220","GO:0044805","GO:0045892","GO:0061504","GO:0016925","GO:0007113","GO:0000422","GO:0051726"]}],"graph":[["XP_005790223.1","XP_005765260.1",0.742],["XP_005790223.1","XP_005762226.1",0.831]],"all_go_terms":{"GO:0055114":1,"GO:0019878":1,"GO:0031146":1,"GO:0038061":1,"GO:0010043":1,"GO:0090263":1,"GO:0090090":1,"GO:0016579":1,"GO:0016032":1,"GO:0002862":1,"GO:0006521":1,"GO:0060071":1,"GO:0002223":1,"GO:0038095":1,"GO:0031145":1,"GO:0002479":1,"GO:0010363":1,"GO:0010972":1,"GO:0080129":1,"GO:0010499":1,"GO:0051437":1,"GO:0043488":1,"GO:0050852":1,"GO:0046686":1,"GO:0061418":1,"GO:0010950":1,"GO:0009651":1,"GO:0051436":1,"GO:0033209":1,"GO:0002143":1,"GO:0051726":1,"GO:0009228":1,"GO:0006777":1,"GO:0018192":1,"GO:0061504":1,"GO:0045116":1,"GO:0007113":1,"GO:0050832":1,"GO:2000220":1,"GO:0006501":1,"GO:0032447":1,"GO:0021764":1,"GO:0034727":1,"GO:0044805":1,"GO:0000422":1,"GO:0009229":1,"GO:1990592":1,"GO:0016236":1,"GO:0045892":1,"GO:0016925":1,"GO:0032258":1},"recipe_readded":[]}