{"hash":"1580529476998143714","title":"DNA Damage Response and Translesion Synthesis","description":"The cluster\u2019s top GO terms center on UV-C\u2013induced cellular responses and DNA damage tolerance during replication, notably both error-free and error-prone translesion synthesis, plus DNA-templated replication. This suggests a theme around coping with DNA lesions during replication (TLS pathways). Some other terms (RNA pseudouridylation, glycosylation, sperm binding) appear incidental to this core, so the label focuses on the UV damage response and TLS connection.","confidence":"Medium","size":4,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_005711802.1","go_terms":["GO:0000455","GO:0031119"]},{"accession":"XP_005716290.1","go_terms":["GO:0071494","GO:0006261","GO:0042276","GO:0070987"]},{"accession":"XP_005719093.1","go_terms":["GO:0015774","GO:0075015","GO:0005989","GO:0060054","GO:0060058","GO:0007341","GO:0006486","GO:0048147","GO:0018146","GO:0060055","GO:0030879","GO:0060046","GO:0007339","GO:0006688","GO:0045136","GO:0021680","GO:0036108","GO:0016266","GO:0030244","GO:0019350","GO:0071555","GO:0006011","GO:0018242","GO:0018243","GO:0030213","GO:0002378"]},{"accession":"XP_005717228.1","go_terms":["GO:0071494","GO:0006297","GO:0042276","GO:0070987","GO:0006261"]}],"graph":[],"all_go_terms":{"GO:0031119":1,"GO:0000455":1,"GO:0071494":2,"GO:0006261":2,"GO:0070987":2,"GO:0042276":2,"GO:0007339":1,"GO:0036108":1,"GO:0018242":1,"GO:0030213":1,"GO:0048147":1,"GO:0018243":1,"GO:0030244":1,"GO:0021680":1,"GO:0007341":1,"GO:0016266":1,"GO:0071555":1,"GO:0060054":1,"GO:0018146":1,"GO:0006688":1,"GO:0060046":1,"GO:0005989":1,"GO:0006011":1,"GO:0045136":1,"GO:0015774":1,"GO:0060058":1,"GO:0006486":1,"GO:0002378":1,"GO:0060055":1,"GO:0019350":1,"GO:0030879":1,"GO:0075015":1,"GO:0006297":1},"recipe_readded":["XP_005711033.1","XP_005709860.1","XP_005717021.1","XP_005717900.1","XP_005716205.1","XP_005714284.1","XP_005715203.1","XP_005712167.1","XP_005716512.1","XP_005715372.1","XP_005717523.1","XP_005711579.1","XP_005712058.1","XP_005711169.1","XP_005713274.1","XP_005715371.1","XP_005710371.1","XP_005718325.1","XP_005715325.1","XP_005718111.1"]}