{"hash":"605918448322792388","title":"GTPase-regulated vesicle trafficking","description":"This cluster is dominated by GO terms involving endosome-lysosome transport, endosome-to-plasma membrane trafficking, lysosomal membrane organization, and exocytosis, all of which point to regulation of vesicle trafficking and membrane dynamics. The presence of small GTPase signaling terms and GTPase activity regulation supports a theme of GTPase-driven control of trafficking, with some actin remodeling context (podosome assembly) that can intertwine with vesicle movement. Overall, the proteins appear to function as regulators of vesicle trafficking rather than core structural components.","confidence":"High","size":4,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_009022181.1","go_terms":[]},{"accession":"XP_009013806.1","go_terms":["GO:0048205","GO:0034379","GO:0061000","GO:0010227","GO:0030037","GO:0035021","GO:1902647","GO:0001675","GO:0043547","GO:1990386","GO:0090162","GO:0045956","GO:0060999","GO:0016477","GO:0097284","GO:0071803","GO:1905751","GO:1902953","GO:1902307","GO:0007624","GO:0033601","GO:0070142","GO:1903527","GO:0007289","GO:0007264","GO:0097212","GO:0055108","GO:1902824","GO:0033028"]},{"accession":"XP_009026903.1","go_terms":[]},{"accession":"XP_009015209.1","go_terms":["GO:0048205","GO:0034379","GO:0061000","GO:0010227","GO:0030037","GO:0035021","GO:1902647","GO:0001675","GO:0043547","GO:1990386","GO:0090162","GO:0045956","GO:0060999","GO:0016477","GO:0097284","GO:0071803","GO:1905751","GO:1902953","GO:1902307","GO:0007624","GO:0033601","GO:0070142","GO:1903527","GO:0007289","GO:0007264","GO:0097212","GO:0055108","GO:1902824","GO:0033028"]}],"graph":[["XP_009026903.1","XP_009013806.1",0.632],["XP_009013806.1","XP_009015209.1",0.844]],"all_go_terms":{"GO:0030037":2,"GO:1902824":2,"GO:0071803":2,"GO:0045956":2,"GO:1905751":2,"GO:0043547":2,"GO:0097212":2,"GO:0010227":2,"GO:0007264":2,"GO:0034379":2,"GO:0033028":2,"GO:0001675":2,"GO:1990386":2,"GO:1903527":2,"GO:1902307":2,"GO:0090162":2,"GO:0070142":2,"GO:0061000":2,"GO:0033601":2,"GO:0060999":2,"GO:0035021":2,"GO:0097284":2,"GO:0016477":2,"GO:1902647":2,"GO:0048205":2,"GO:0007289":2,"GO:0055108":2,"GO:0007624":2,"GO:1902953":2},"recipe_readded":["XP_009009750.1","XP_009026450.1","XP_009026505.1","XP_009031498.1","XP_009009682.1","XP_009023323.1","XP_009009413.1","XP_009022187.1","XP_009013912.1","XP_009028518.1","XP_009024757.1","XP_009031696.1","XP_009010979.1","XP_009018710.1","XP_009023681.1","XP_009030424.1","XP_009012036.1","XP_009016013.1","XP_009022804.1","XP_009030785.1"]}