{"hash":"1810354242383993485","title":"Symbiont-Mediated Immune Suppression and Ubiquitination","description":"The cluster is dominated by GO terms pointing to host immune modulation by symbionts, including suppression of adaptive immune responses and altered antigen processing/presentation via MHC II, along with ubiquitin-related pathways (ubiquitin-like modifications and polyubiquitination). A few terms about barrier biosynthesis (cutin/suberin) appear but are secondary to the main theme of immune modulation through ubiquitin-related processes. Confidence in this naming is High because the immune modulation and ubiquitination signals strongly align across multiple terms.","confidence":"High","size":22,"edges":107,"triangles":300,"max_degree":15,"top_function":null,"members":[{"accession":"XP_011772851.1","go_terms":[]},{"accession":"XP_011779322.1","go_terms":[]},{"accession":"XP_011772187.1","go_terms":["GO:0031648","GO:0016558","GO:0048147","GO:0006513","GO:0007112","GO:0007285","GO:0010381","GO:0000038","GO:0009640","GO:0048137"]},{"accession":"XP_011772412.1","go_terms":["GO:0010143","GO:0045347","GO:0002643","GO:0039648","GO:0002495","GO:0000209","GO:1900490","GO:0010345","GO:0039504"]},{"accession":"XP_011772973.1","go_terms":[]},{"accession":"XP_011772978.1","go_terms":[]},{"accession":"XP_011773081.1","go_terms":["GO:0001306","GO:0050881","GO:0021523","GO:0050884","GO:0060052","GO:1905045","GO:0051935","GO:0046513","GO:0032964","GO:0044257","GO:0002238","GO:1900148"]},{"accession":"XP_011776778.1","go_terms":[]},{"accession":"XP_011777197.1","go_terms":["GO:0016255","GO:0045313"]},{"accession":"XP_011777988.1","go_terms":["GO:0032525","GO:0006888","GO:0001893","GO:0090161","GO:0006621","GO:0061357","GO:0048042","GO:0007311","GO:0048205","GO:0002121","GO:0035964","GO:0070863","GO:1902003"]},{"accession":"XP_011779789.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_011780509.1","go_terms":[]},{"accession":"XP_011774917.1","go_terms":[]},{"accession":"XP_011779442.1","go_terms":["GO:0019375"]},{"accession":"XP_011771955.1","go_terms":["GO:0006824","GO:0030253","GO:0030153","GO:0017004","GO:0031460","GO:0010949","GO:0046677","GO:0009432","GO:0099040","GO:0046618","GO:0042883","GO:0015734","GO:0008643","GO:0042760","GO:0015910","GO:1900753","GO:0015777","GO:0006855","GO:0019885","GO:0099133","GO:0090374","GO:0046689","GO:0060702","GO:0006289","GO:0015821","GO:0045332","GO:0015803","GO:0000770","GO:0015888","GO:0035461","GO:0043213","GO:0045796","GO:0003333","GO:0043215","GO:0001407","GO:0042953","GO:0072089","GO:0015689","GO:0015886"]},{"accession":"XP_011774746.1","go_terms":["GO:0032525","GO:0006888","GO:0001893","GO:0090161","GO:0006621","GO:0061357","GO:0048042","GO:0007311","GO:0048205","GO:0002121","GO:0035964","GO:0070863","GO:1902003"]},{"accession":"XP_011771573.1","go_terms":["GO:0006824","GO:0030253","GO:0030153","GO:0017004","GO:0031460","GO:0010949","GO:0046677","GO:0009432","GO:0099040","GO:0046618","GO:0042883","GO:0015734","GO:0008643","GO:0042760","GO:0015910","GO:1900753","GO:0015777","GO:0006855","GO:0019885","GO:0099133","GO:0090374","GO:0046689","GO:0060702","GO:0006289","GO:0015821","GO:0045332","GO:0015803","GO:0000770","GO:0015888","GO:0035461","GO:0043213","GO:0045796","GO:0003333","GO:0043215","GO:0001407","GO:0042953","GO:0072089","GO:0015689","GO:0015886"]},{"accession":"XP_011774337.1","go_terms":[]},{"accession":"XP_011776892.1","go_terms":[]},{"accession":"XP_011775371.1","go_terms":[]},{"accession":"XP_011777486.1","go_terms":["GO:0006915","GO:0033081"]},{"accession":"XP_011780967.1","go_terms":["GO:0010143","GO:0045347","GO:0002643","GO:0039648","GO:0002495","GO:0000209","GO:1900490","GO:0010345","GO:0039504"]}],"graph":[["XP_011775371.1","XP_011771573.1",0.646],["XP_011775371.1","XP_011771955.1",0.58],["XP_011775371.1","XP_011772187.1",0.616],["XP_011775371.1","XP_011772978.1",0.599],["XP_011775371.1","XP_011773081.1",0.51],["XP_011775371.1","XP_011774337.1",0.583],["XP_011775371.1","XP_011780967.1",0.506],["XP_011775371.1","XP_011779789.1",0.564],["XP_011775371.1","XP_011779442.1",0.594],["XP_011775371.1","XP_011777197.1",0.591],["XP_011775371.1","XP_011777486.1",0.628],["XP_011775371.1","XP_011776892.1",0.537],["XP_011771573.1","XP_011771955.1",0.699],["XP_011771573.1","XP_011772187.1",0.708],["XP_011771573.1","XP_011772412.1",0.581],["XP_011771573.1","XP_011772978.1",0.718],["XP_011771573.1","XP_011774337.1",0.69],["XP_011771573.1","XP_011774746.1",0.594],["XP_011771573.1","XP_011776892.1",0.716],["XP_011771573.1","XP_011777197.1",0.653],["XP_011771573.1","XP_011777486.1",0.619],["XP_011771573.1","XP_011777988.1",0.614],["XP_011771573.1","XP_011779442.1",0.711],["XP_011771573.1","XP_011779789.1",0.659],["XP_011771573.1","XP_011780967.1",0.699],["XP_011773081.1","XP_011771955.1",0.597],["XP_011773081.1","XP_011772187.1",0.56],["XP_011773081.1","XP_011772412.1",0.523],["XP_011773081.1","XP_011780967.1",0.515],["XP_011773081.1","XP_011777486.1",0.591],["XP_011777486.1","XP_011771955.1",0.639],["XP_011777486.1","XP_011772187.1",0.604],["XP_011777486.1","XP_011772412.1",0.59],["XP_011777486.1","XP_011772978.1",0.563],["XP_011777486.1","XP_011774337.1",0.628],["XP_011777486.1","XP_011774746.1",0.545],["XP_011777486.1","XP_011776892.1",0.626],["XP_011777486.1","XP_011777197.1",0.64],["XP_011777486.1","XP_011777988.1",0.535],["XP_011777486.1","XP_011779442.1",0.525],["XP_011777486.1","XP_011779789.1",0.628],["XP_011777486.1","XP_011780967.1",0.624],["XP_011772187.1","XP_011774746.1",0.503],["XP_011772187.1","XP_011774337.1",0.657],["XP_011772187.1","XP_011772978.1",0.63],["XP_011772187.1","XP_011771955.1",0.738],["XP_011772187.1","XP_011772412.1",0.616],["XP_011772187.1","XP_011780967.1",0.635],["XP_011772187.1","XP_011779789.1",0.656],["XP_011772187.1","XP_011779442.1",0.7],["XP_011772187.1","XP_011777197.1",0.581],["XP_011772187.1","XP_011776892.1",0.586],["XP_011779322.1","XP_011772851.1",0.584],["XP_011779322.1","XP_011772973.1",0.629],["XP_011779322.1","XP_011774917.1",0.67],["XP_011779322.1","XP_011776778.1",0.739],["XP_011779322.1","XP_011780509.1",0.63],["XP_011777988.1","XP_011771955.1",0.55],["XP_011777988.1","XP_011774337.1",0.668],["XP_011777988.1","XP_011774746.1",0.667],["XP_011777988.1","XP_011776892.1",0.617],["XP_011777988.1","XP_011777197.1",0.553],["XP_011777988.1","XP_011779789.1",0.534],["XP_011779789.1","XP_011772978.1",0.617],["XP_011779789.1","XP_011774337.1",0.514],["XP_011779789.1","XP_011774746.1",0.602],["XP_011779789.1","XP_011777197.1",0.541],["XP_011776778.1","XP_011772851.1",0.702],["XP_011776778.1","XP_011772973.1",0.708],["XP_011776778.1","XP_011774917.1",0.737],["XP_011776778.1","XP_011780509.1",0.667],["XP_011772851.1","XP_011774917.1",0.591],["XP_011772851.1","XP_011772973.1",0.565],["XP_011772851.1","XP_011780509.1",0.622],["XP_011779442.1","XP_011771955.1",0.71],["XP_011779442.1","XP_011772412.1",0.521],["XP_011779442.1","XP_011772978.1",0.688],["XP_011779442.1","XP_011774337.1",0.691],["XP_011779442.1","XP_011776892.1",0.624],["XP_011779442.1","XP_011777197.1",0.564],["XP_011779442.1","XP_011780967.1",0.646],["XP_011776892.1","XP_011771955.1",0.709],["XP_011776892.1","XP_011772412.1",0.556],["XP_011776892.1","XP_011774337.1",0.708],["XP_011776892.1","XP_011774746.1",0.658],["XP_011776892.1","XP_011780967.1",0.533],["XP_011776892.1","XP_011777197.1",0.591],["XP_011772978.1","XP_011771955.1",0.693],["XP_011772978.1","XP_011772412.1",0.521],["XP_011772978.1","XP_011774337.1",0.594],["XP_011772978.1","XP_011780967.1",0.511],["XP_011772978.1","XP_011777197.1",0.634],["XP_011772973.1","XP_011774917.1",0.616],["XP_011772973.1","XP_011780509.1",0.615],["XP_011774746.1","XP_011774337.1",0.633],["XP_011774746.1","XP_011777197.1",0.523],["XP_011772412.1","XP_011771955.1",0.602],["XP_011772412.1","XP_011774337.1",0.548],["XP_011772412.1","XP_011777197.1",0.694],["XP_011772412.1","XP_011780967.1",0.623],["XP_011780509.1","XP_011774917.1",0.665],["XP_011771955.1","XP_011774337.1",0.696],["XP_011771955.1","XP_011780967.1",0.696],["XP_011771955.1","XP_011777197.1",0.621],["XP_011777197.1","XP_011774337.1",0.613],["XP_011777197.1","XP_011780967.1",0.573],["XP_011780967.1","XP_011774337.1",0.566]],"all_go_terms":{"GO:0048147":1,"GO:0016558":1,"GO:0010381":1,"GO:0007112":1,"GO:0006513":1,"GO:0007285":1,"GO:0031648":1,"GO:0000038":1,"GO:0048137":1,"GO:0009640":1,"GO:0010143":2,"GO:0000209":2,"GO:0002495":2,"GO:0010345":2,"GO:0039648":2,"GO:0045347":2,"GO:0002643":2,"GO:1900490":2,"GO:0039504":2,"GO:0044257":1,"GO:0050884":1,"GO:0032964":1,"GO:0002238":1,"GO:0046513":1,"GO:0060052":1,"GO:1900148":1,"GO:0001306":1,"GO:0050881":1,"GO:1905045":1,"GO:0051935":1,"GO:0021523":1,"GO:0016255":1,"GO:0045313":1,"GO:0070863":2,"GO:1902003":2,"GO:0061357":2,"GO:0035964":2,"GO:0001893":2,"GO:0090161":2,"GO:0007311":2,"GO:0006888":2,"GO:0002121":2,"GO:0048205":2,"GO:0006621":2,"GO:0032525":2,"GO:0048042":2,"GO:0071374":1,"GO:0036494":1,"GO:0006626":1,"GO:0051259":1,"GO:0006452":1,"GO:1900035":1,"GO:0006458":1,"GO:0030433":1,"GO:0035719":1,"GO:1901621":1,"GO:0006260":1,"GO:0032781":1,"GO:0006469":1,"GO:0070389":1,"GO:0090084":1,"GO:0006986":1,"GO:0031204":1,"GO:0071630":1,"GO:0001707":1,"GO:0034975":1,"GO:0009408":1,"GO:0045454":1,"GO:0046825":1,"GO:0097428":1,"GO:0070843":1,"GO:0019375":1,"GO:0015821":2,"GO:0043215":2,"GO:0015803":2,"GO:0015689":2,"GO:0003333":2,"GO:0006289":2,"GO:0045796":2,"GO:0099133":2,"GO:0015910":2,"GO:0009432":2,"GO:0015888":2,"GO:0043213":2,"GO:0006855":2,"GO:0001407":2,"GO:0010949":2,"GO:0060702":2,"GO:0090374":2,"GO:0045332":2,"GO:0072089":2,"GO:0006824":2,"GO:0042760":2,"GO:0046618":2,"GO:0030253":2,"GO:0015777":2,"GO:0019885":2,"GO:0099040":2,"GO:0046677":2,"GO:0000770":2,"GO:0035461":2,"GO:0031460":2,"GO:0008643":2,"GO:0030153":2,"GO:0015886":2,"GO:0015734":2,"GO:0046689":2,"GO:0017004":2,"GO:1900753":2,"GO:0042883":2,"GO:0042953":2,"GO:0033081":1,"GO:0006915":1},"recipe_readded":[]}