{"hash":"33795645502181360","title":"Acrosome formation via Golgi-lysosome trafficking","description":"This cluster is best described by terms tied to intracellular transport and organelle biogenesis related to the acrosome, a lysosome-derived organelle formed through Golgi trafficking (acrosome assembly; Golgi-to-vacuole transport; lysosomal transport; endosome-to-Golgi retrograde transport). The ubiquitin-proteasome\u2013mediated cytoplasmic quality control also fits the broader protein handling context during organelle formation. Some terms like spermatid nucleus elongation and suckling behavior are less directly connected and may reflect broader developmental contexts. Overall, the set centers on acrosome biogenesis linked to Golgi-lysosome trafficking.","confidence":"Medium","size":8,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_001013161.1","go_terms":["GO:0050881","GO:0048873","GO:0006896","GO:0060052","GO:0007290","GO:0007041","GO:0042147","GO:0001675"]},{"accession":"XP_001016286.2","go_terms":["GO:1990116","GO:0071233","GO:1901718","GO:0001967","GO:0071629","GO:0032007","GO:0070923","GO:0033522","GO:0071596","GO:0007141"]},{"accession":"XP_001032067.1","go_terms":["GO:0034453","GO:0043552","GO:0030593","GO:0030890","GO:0030032","GO:0045954","GO:0050853","GO:0035023","GO:0045218","GO:0090136","GO:0031175","GO:0007229"]},{"accession":"XP_001029430.3","go_terms":["GO:0048565","GO:0021510","GO:0072177","GO:0001502","GO:0001889","GO:0072287","GO:0060674","GO:0036303","GO:0032092","GO:0050982","GO:0031659","GO:0072205","GO:0001822","GO:0007259","GO:0048806","GO:2000171","GO:0043588","GO:0021915","GO:0060428","GO:0060236","GO:0003127","GO:0042994","GO:0001892","GO:0072218","GO:0072237","GO:0034405"]},{"accession":"XP_001020869.2","go_terms":[]},{"accession":"XP_001022381.2","go_terms":[]},{"accession":"XP_001029599.2","go_terms":[]},{"accession":"XP_001009421.2","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0007290":1,"GO:0060052":1,"GO:0050881":1,"GO:0048873":1,"GO:0042147":1,"GO:0007041":1,"GO:0001675":1,"GO:0006896":1,"GO:0071629":1,"GO:0001967":1,"GO:0033522":1,"GO:1901718":1,"GO:0070923":1,"GO:0007141":1,"GO:0071596":1,"GO:1990116":1,"GO:0071233":1,"GO:0032007":1,"GO:0034453":1,"GO:0035023":1,"GO:0030890":1,"GO:0045954":1,"GO:0043552":1,"GO:0050853":1,"GO:0045218":1,"GO:0007229":1,"GO:0090136":1,"GO:0030032":1,"GO:0030593":1,"GO:0031175":1,"GO:0031659":1,"GO:0048806":1,"GO:0060674":1,"GO:0007259":1,"GO:0001822":1,"GO:0021915":1,"GO:0072287":1,"GO:0001889":1,"GO:0072205":1,"GO:0043588":1,"GO:0021510":1,"GO:0072237":1,"GO:0003127":1,"GO:0034405":1,"GO:2000171":1,"GO:0001502":1,"GO:0072218":1,"GO:0001892":1,"GO:0060236":1,"GO:0042994":1,"GO:0036303":1,"GO:0060428":1,"GO:0048565":1,"GO:0072177":1,"GO:0050982":1,"GO:0032092":1},"recipe_readded":["XP_001009807.2","XP_001027964.1","XP_001008210.3","XP_001033383.1","XP_001025131.1","XP_001030578.2","XP_001031859.2","XP_977058.3","XP_001032481.1","XP_001012497.1","XP_001016725.1","XP_001021884.3","XP_977008.1","XP_001031297.1","XP_012656257.1"]}