{"hash":"2167409613544538762","title":"GTPase signaling and cardiac sarcomere regulation","description":"The top GO terms cluster around small GTPase-mediated signaling (including Ras and GPCR-related pathways) and modulation of cyclic nucleotide signaling (adenylate and guanylyl cyclase pathways), with supporting terms on sarcomere organization and cardiac muscle cell proliferation. This suggests a theme of signaling pathways that influence cardiac muscle structure and growth, even though a few outlier terms are present. ","confidence":"Medium","size":29,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_001017009.2","go_terms":[]},{"accession":"XP_001017953.2","go_terms":["GO:0098719","GO:1902600","GO:1903281","GO:0030007","GO:0051595","GO:0031547","GO:0009651","GO:0097623","GO:0007035","GO:0006884","GO:0036376","GO:0086092"]},{"accession":"XP_001018737.1","go_terms":[]},{"accession":"XP_001019525.1","go_terms":[]},{"accession":"XP_001021967.2","go_terms":[]},{"accession":"XP_001022638.2","go_terms":[]},{"accession":"XP_001024647.2","go_terms":[]},{"accession":"XP_001025881.2","go_terms":[]},{"accession":"XP_001026606.2","go_terms":[]},{"accession":"XP_001026720.1","go_terms":[]},{"accession":"XP_001033214.2","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975","GO:0010259","GO:0000393","GO:0000712","GO:0000388","GO:0051026","GO:0002181","GO:0072001","GO:0008380","GO:0006397"]},{"accession":"XP_001470737.2","go_terms":[]},{"accession":"XP_012655376.1","go_terms":[]},{"accession":"XP_012655562.1","go_terms":[]},{"accession":"XP_976839.1","go_terms":["GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"XP_001027301.2","go_terms":["GO:0042391","GO:0098719","GO:0046007","GO:0009454","GO:0007608","GO:0045013","GO:0071805","GO:0045762","GO:0002027","GO:0097338","GO:0097332","GO:0060038","GO:2000480","GO:0045214","GO:0046580","GO:0007264","GO:0034638","GO:0051447","GO:0071321","GO:0071320","GO:0097271","GO:0046827","GO:0006351","GO:0010754"]},{"accession":"XP_001032169.2","go_terms":[]},{"accession":"XP_001021112.2","go_terms":[]},{"accession":"XP_001013724.2","go_terms":[]},{"accession":"XP_001013739.2","go_terms":["GO:0042391","GO:0098719","GO:0046007","GO:0009454","GO:0007608","GO:0045013","GO:0071805","GO:0045762","GO:0002027","GO:0097338","GO:0097332","GO:0060038","GO:2000480","GO:0045214","GO:0046580","GO:0007264","GO:0034638","GO:0051447","GO:0071321","GO:0071320","GO:0097271","GO:0046827","GO:0006351","GO:0010754"]},{"accession":"XP_012655677.1","go_terms":[]},{"accession":"XP_012651282.1","go_terms":[]},{"accession":"XP_012656140.1","go_terms":[]},{"accession":"XP_001016801.2","go_terms":[]},{"accession":"XP_001024084.1","go_terms":[]},{"accession":"XP_001026643.2","go_terms":[]},{"accession":"XP_012651458.1","go_terms":[]},{"accession":"XP_001017638.1","go_terms":[]},{"accession":"XP_001026383.2","go_terms":[]}],"graph":[["XP_001013739.2","XP_001026606.2",0.909],["XP_001013739.2","XP_012651282.1",0.72]],"all_go_terms":{"GO:0051595":1,"GO:1903281":1,"GO:0009651":1,"GO:0086092":1,"GO:0006884":1,"GO:1902600":1,"GO:0098719":3,"GO:0036376":1,"GO:0030007":1,"GO:0097623":1,"GO:0007035":1,"GO:0031547":1,"GO:1901621":1,"GO:0010259":1,"GO:1900035":1,"GO:0036494":1,"GO:0070389":1,"GO:0009408":1,"GO:0000388":1,"GO:0001707":1,"GO:0000712":1,"GO:0008380":1,"GO:0006458":1,"GO:0006469":1,"GO:0006626":1,"GO:0045454":1,"GO:0046825":1,"GO:0006397":1,"GO:0031204":1,"GO:0071630":1,"GO:0051259":1,"GO:0006452":1,"GO:0035719":1,"GO:0072001":1,"GO:0002181":1,"GO:0071374":1,"GO:0006986":1,"GO:0000393":1,"GO:0070843":1,"GO:0006260":1,"GO:0051026":1,"GO:0034975":1,"GO:0030433":1,"GO:0090084":1,"GO:0032781":1,"GO:0097428":1,"GO:0050435":1,"GO:0007586":1,"GO:0002018":1,"GO:0001823":1,"GO:0016540":1,"GO:0042756":1,"GO:0002016":1,"GO:0002003":1,"GO:0033619":1,"GO:0002803":1,"GO:0042985":1,"GO:0019886":1,"GO:0070305":1,"GO:0051447":2,"GO:0046580":2,"GO:0045214":2,"GO:0007264":2,"GO:0097332":2,"GO:0010754":2,"GO:0009454":2,"GO:0060038":2,"GO:0045762":2,"GO:0046007":2,"GO:0042391":2,"GO:0006351":2,"GO:0045013":2,"GO:0097338":2,"GO:0097271":2,"GO:0071321":2,"GO:0002027":2,"GO:2000480":2,"GO:0034638":2,"GO:0071320":2,"GO:0007608":2,"GO:0071805":2,"GO:0046827":2},"recipe_readded":["XP_001016283.2","XP_001019066.2","XP_001021377.1","XP_001018185.1","XP_001021692.2","XP_001026885.3","XP_976827.1","XP_001016943.1","XP_001021020.2","XP_001015733.3","XP_001029927.2","XP_977055.3","XP_001009909.2","XP_001017357.2","XP_001026185.2","XP_001026161.2","XP_001008153.1","XP_001021699.2","XP_001015983.1","XP_001010735.4"]}