{"hash":"1239904797713467848","title":"Nuclear gene expression and ribosome biogenesis","description":"The GO terms center on nuclear processes: rRNA processing (endonuclolytic cleavage in ITS1 for separating rRNA components) and regulation of transcription, plus nuclear transport and DNA topology changes, suggesting a coherent theme of nuclear gene expression control and ribosome assembly. Some terms appear less directly related (otolith tethering, tetrapyrrole linkage), likely reflecting annotation noise or multifunctional proteins. Overall, the cluster seems to represent nuclear regulation of gene expression with a focus on ribosome biogenesis.","confidence":"Medium","size":20,"edges":6,"triangles":0,"max_degree":6,"top_function":null,"members":[{"accession":"XP_004987512.1","go_terms":[]},{"accession":"XP_004996488.1","go_terms":[]},{"accession":"XP_004994487.1","go_terms":["GO:0006457","GO:0006298","GO:0017006","GO:0035690","GO:0010105","GO:0046777","GO:0009585","GO:0070483","GO:0000160","GO:0071353","GO:0006265","GO:0006261","GO:0097411","GO:0033160","GO:0009584","GO:0006935","GO:0018298","GO:1903660","GO:0042220","GO:0007059","GO:0001890","GO:0045793","GO:0080117","GO:1901389","GO:0006355","GO:0010510","GO:0006006","GO:1905323","GO:0019062","GO:1901856","GO:0032435","GO:0031247","GO:0045429","GO:0043524","GO:0009651","GO:0071902","GO:0060338","GO:0007004","GO:0032092","GO:2000010","GO:0030511","GO:0071318","GO:0071157","GO:0032516","GO:0051131","GO:0060334","GO:0009386","GO:0035889","GO:0051973"]},{"accession":"XP_004988310.1","go_terms":["GO:0034635","GO:0002229"]},{"accession":"XP_004998651.1","go_terms":["GO:0051123","GO:0030520","GO:0035067","GO:0006367","GO:0000296"]},{"accession":"XP_004995377.1","go_terms":[]},{"accession":"XP_004991138.1","go_terms":["GO:0000447"]},{"accession":"XP_004988748.1","go_terms":["GO:0009553","GO:0000920","GO:0000462","GO:0000472","GO:0030010","GO:0000447","GO:0000480"]},{"accession":"XP_004990164.1","go_terms":[]},{"accession":"XP_004990422.1","go_terms":["GO:0008355"]},{"accession":"XP_004987576.1","go_terms":[]},{"accession":"XP_004990595.1","go_terms":[]},{"accession":"XP_004991842.1","go_terms":[]},{"accession":"XP_004993591.1","go_terms":[]},{"accession":"XP_004994392.1","go_terms":[]},{"accession":"XP_004994427.1","go_terms":[]},{"accession":"XP_004994428.1","go_terms":["GO:0032973","GO:1990034","GO:0030206","GO:0036066","GO:1990536","GO:0035436","GO:0036071","GO:0080147","GO:0015786","GO:0036085","GO:0015713","GO:0048527"]},{"accession":"XP_004996459.1","go_terms":["GO:0009306","GO:0016192"]},{"accession":"XP_004995937.1","go_terms":[]},{"accession":"XP_004998258.1","go_terms":[]}],"graph":[["XP_004991138.1","XP_004994487.1",0.542],["XP_004998651.1","XP_004994487.1",0.632],["XP_004994487.1","XP_004988310.1",0.507],["XP_004994487.1","XP_004988748.1",0.533],["XP_004994487.1","XP_004998258.1",0.68],["XP_004994487.1","XP_004995377.1",0.789]],"all_go_terms":{"GO:0006265":1,"GO:0009386":1,"GO:0033160":1,"GO:0006355":1,"GO:0017006":1,"GO:0045793":1,"GO:0071157":1,"GO:0035889":1,"GO:0032092":1,"GO:0070483":1,"GO:0009584":1,"GO:0043524":1,"GO:0010510":1,"GO:0032516":1,"GO:0097411":1,"GO:0006006":1,"GO:0009585":1,"GO:0009651":1,"GO:0046777":1,"GO:0007004":1,"GO:0007059":1,"GO:0071902":1,"GO:2000010":1,"GO:0080117":1,"GO:0018298":1,"GO:0031247":1,"GO:0000160":1,"GO:0071353":1,"GO:1901389":1,"GO:1905323":1,"GO:0060334":1,"GO:0001890":1,"GO:0019062":1,"GO:0006457":1,"GO:0006298":1,"GO:0060338":1,"GO:0035690":1,"GO:0045429":1,"GO:0071318":1,"GO:0051131":1,"GO:0042220":1,"GO:0006935":1,"GO:0032435":1,"GO:0030511":1,"GO:1903660":1,"GO:0010105":1,"GO:0006261":1,"GO:1901856":1,"GO:0051973":1,"GO:0034635":1,"GO:0002229":1,"GO:0035067":1,"GO:0000296":1,"GO:0030520":1,"GO:0006367":1,"GO:0051123":1,"GO:0000447":2,"GO:0000472":1,"GO:0000920":1,"GO:0030010":1,"GO:0000480":1,"GO:0000462":1,"GO:0009553":1,"GO:0008355":1,"GO:0030206":1,"GO:0080147":1,"GO:1990034":1,"GO:0036066":1,"GO:0036085":1,"GO:0048527":1,"GO:0032973":1,"GO:0015713":1,"GO:0015786":1,"GO:0035436":1,"GO:0036071":1,"GO:1990536":1,"GO:0009306":1,"GO:0016192":1},"recipe_readded":["XP_004997014.1","XP_004994533.1","XP_004996890.1","XP_004996754.1","XP_004992677.1","XP_004998821.1","XP_004998132.1","XP_004997160.1","XP_004991356.1","XP_004989976.1","XP_004995462.1","XP_004990570.1","XP_004993197.1","XP_004995796.1","XP_004992440.1","XP_004994740.1","XP_004993106.1","XP_004987743.1","XP_004991444.1","XP_004987583.1"]}