{"hash":"9017815986219010","title":"Oxidative stress\u2013induced mitochondrial apoptosis","description":"These proteins show a cohesive pattern around intrinsic apoptotic signaling in response to oxidative stress and regulation of mitochondrial membrane potential, with support from inositol phosphoceramide metabolism (a sphingolipid pathway linked to stress-induced cell death). An ER-to-Golgi transport term is present but does not dominate the signal, so the dominant theme is stress-responsive, mitochondria-mediated apoptosis. ","confidence":"Medium","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_019330660.1","go_terms":["GO:0002037","GO:0006888","GO:0008631","GO:0010917"]},{"accession":"XP_019330718.1","go_terms":[]},{"accession":"XP_019330694.1","go_terms":["GO:0006673"]}],"graph":[["XP_019330660.1","XP_019330718.1",0.544],["XP_019330694.1","XP_019330718.1",0.686]],"all_go_terms":{"GO:0006888":1,"GO:0002037":1,"GO:0008631":1,"GO:0010917":1,"GO:0006673":1},"recipe_readded":[]}