{"hash":"679227024091287097","title":"Amino acid biosynthesis and redox metabolism","description":"The cluster shows enrichment for amino acid biosynthetic processes (L-leucine, 2-oxoglutarate and lysine pathways) along with redox-related activities (NADP+/NADPH biosynthesis/regeneration, glutathione metabolism, and responses to oxidative stress). This combination points to proteins co-involved in balancing amino acid production with cellular redox homeostasis. Some terms related to development (female gonad development, response to steroid hormone, glial migration) appear less central to the core theme and may be incidental noise. Overall, the dominant theme is metabolic pathways tied to redox balance and amino acid supply.","confidence":"Medium","size":15,"edges":95,"triangles":339,"max_degree":14,"top_function":null,"members":[{"accession":"XP_718193.1","go_terms":["GO:0008585","GO:0006099","GO:0006097","GO:0019878","GO:1903976","GO:0006749","GO:0071071","GO:0006740","GO:0009098","GO:1904465","GO:0060253","GO:0006979","GO:0006537","GO:0006741","GO:0006103","GO:0006102","GO:0060696","GO:0048545"]},{"accession":"XP_718120.1","go_terms":[]},{"accession":"XP_712022.1","go_terms":["GO:0032543"]},{"accession":"XP_714621.1","go_terms":[]},{"accession":"XP_714688.2","go_terms":["GO:0070124"]},{"accession":"XP_714864.1","go_terms":["GO:0006412"]},{"accession":"XP_715023.1","go_terms":[]},{"accession":"XP_715053.2","go_terms":["GO:0006366","GO:0042254","GO:0001172","GO:0006360","GO:0006386","GO:0006385","GO:0042797"]},{"accession":"XP_712487.1","go_terms":["GO:0033615"]},{"accession":"XP_716459.1","go_terms":["GO:0006878","GO:0008535","GO:0006825","GO:0007308","GO:0045454"]},{"accession":"XP_721485.1","go_terms":["GO:1900208","GO:0000001"]},{"accession":"XP_711161.1","go_terms":[]},{"accession":"XP_713130.1","go_terms":[]},{"accession":"XP_715703.2","go_terms":["GO:0006744","GO:1904808"]},{"accession":"XP_722220.1","go_terms":["GO:0097428","GO:0036086","GO:0034396","GO:0044571","GO:0051220","GO:1903026"]}],"graph":[["XP_715023.1","XP_711161.1",0.974],["XP_715023.1","XP_712022.1",0.962],["XP_715023.1","XP_712487.1",0.964],["XP_715023.1","XP_713130.1",0.954],["XP_715023.1","XP_714621.1",0.982],["XP_715023.1","XP_714688.2",0.979],["XP_715023.1","XP_714864.1",0.983],["XP_715023.1","XP_715053.2",0.837],["XP_715023.1","XP_715703.2",0.985],["XP_715023.1","XP_716459.1",0.955],["XP_715023.1","XP_718120.1",0.923],["XP_715023.1","XP_718193.1",0.92],["XP_715023.1","XP_721485.1",0.959],["XP_715023.1","XP_722220.1",0.708],["XP_721485.1","XP_712022.1",0.645],["XP_721485.1","XP_712487.1",0.98],["XP_721485.1","XP_713130.1",0.957],["XP_721485.1","XP_714621.1",0.519],["XP_721485.1","XP_714688.2",0.67],["XP_721485.1","XP_714864.1",0.918],["XP_721485.1","XP_715053.2",0.967],["XP_721485.1","XP_715703.2",0.809],["XP_721485.1","XP_716459.1",0.813],["XP_721485.1","XP_718120.1",0.76],["XP_721485.1","XP_722220.1",0.878],["XP_715703.2","XP_711161.1",0.957],["XP_715703.2","XP_712022.1",0.966],["XP_715703.2","XP_712487.1",0.972],["XP_715703.2","XP_713130.1",0.984],["XP_715703.2","XP_714621.1",0.967],["XP_715703.2","XP_714688.2",0.935],["XP_715703.2","XP_714864.1",0.871],["XP_715703.2","XP_715053.2",0.982],["XP_715703.2","XP_716459.1",0.59],["XP_715703.2","XP_718120.1",0.977],["XP_715703.2","XP_718193.1",0.876],["XP_715703.2","XP_722220.1",0.779],["XP_713130.1","XP_711161.1",0.977],["XP_713130.1","XP_712022.1",0.951],["XP_713130.1","XP_712487.1",0.975],["XP_713130.1","XP_714621.1",0.981],["XP_713130.1","XP_714688.2",0.595],["XP_713130.1","XP_714864.1",0.966],["XP_713130.1","XP_715053.2",0.933],["XP_713130.1","XP_716459.1",0.906],["XP_713130.1","XP_718120.1",0.881],["XP_713130.1","XP_718193.1",0.725],["XP_713130.1","XP_722220.1",0.928],["XP_722220.1","XP_712487.1",0.785],["XP_722220.1","XP_714864.1",0.523],["XP_722220.1","XP_715053.2",0.949],["XP_722220.1","XP_716459.1",0.755],["XP_722220.1","XP_718120.1",0.855],["XP_722220.1","XP_718193.1",0.607],["XP_714621.1","XP_711161.1",0.92],["XP_714621.1","XP_712022.1",0.938],["XP_714621.1","XP_712487.1",0.931],["XP_714621.1","XP_718120.1",0.975],["XP_714621.1","XP_718193.1",0.548],["XP_714621.1","XP_716459.1",0.598],["XP_714621.1","XP_714688.2",0.8],["XP_714621.1","XP_714864.1",0.985],["XP_714621.1","XP_715053.2",0.887],["XP_716459.1","XP_711161.1",0.923],["XP_716459.1","XP_712022.1",0.694],["XP_716459.1","XP_712487.1",0.862],["XP_716459.1","XP_714864.1",0.925],["XP_716459.1","XP_715053.2",0.966],["XP_716459.1","XP_718120.1",0.785],["XP_716459.1","XP_718193.1",0.553],["XP_714864.1","XP_711161.1",0.852],["XP_714864.1","XP_712022.1",0.944],["XP_714864.1","XP_712487.1",0.986],["XP_714864.1","XP_714688.2",0.893],["XP_714864.1","XP_715053.2",0.925],["XP_714864.1","XP_718120.1",0.928],["XP_714864.1","XP_718193.1",0.723],["XP_718193.1","XP_711161.1",0.565],["XP_718193.1","XP_712022.1",0.879],["XP_718193.1","XP_715053.2",0.533],["XP_718193.1","XP_718120.1",0.535],["XP_712487.1","XP_711161.1",0.839],["XP_712487.1","XP_712022.1",0.956],["XP_712487.1","XP_714688.2",0.85],["XP_712487.1","XP_715053.2",0.972],["XP_712487.1","XP_718120.1",0.879],["XP_715053.2","XP_711161.1",0.968],["XP_715053.2","XP_712022.1",0.88],["XP_715053.2","XP_714688.2",0.953],["XP_711161.1","XP_718120.1",0.956],["XP_711161.1","XP_714688.2",0.702],["XP_711161.1","XP_712022.1",0.915],["XP_718120.1","XP_712022.1",0.676],["XP_718120.1","XP_714688.2",0.856],["XP_714688.2","XP_712022.1",0.735]],"all_go_terms":{"GO:0009098":1,"GO:0008585":1,"GO:0006103":1,"GO:0006741":1,"GO:0019878":1,"GO:0006749":1,"GO:1903976":1,"GO:0048545":1,"GO:0006740":1,"GO:0006979":1,"GO:0006537":1,"GO:0060696":1,"GO:1904465":1,"GO:0060253":1,"GO:0006097":1,"GO:0006102":1,"GO:0071071":1,"GO:0006099":1,"GO:0032543":1,"GO:0070124":1,"GO:0006412":1,"GO:0006360":1,"GO:0006366":1,"GO:0042797":1,"GO:0001172":1,"GO:0006386":1,"GO:0042254":1,"GO:0006385":1,"GO:0033615":1,"GO:0045454":1,"GO:0007308":1,"GO:0006825":1,"GO:0006878":1,"GO:0008535":1,"GO:0000001":1,"GO:1900208":1,"GO:1904808":1,"GO:0006744":1,"GO:0036086":1,"GO:0044571":1,"GO:0034396":1,"GO:0051220":1,"GO:0097428":1,"GO:1903026":1},"recipe_readded":[]}