{"hash":"675751323034503989","title":"Mitochondrial respiration, translation, and genome maintenance","description":"The cluster is dominated by mitochondrial functions: electron transport and complex IV assembly point to respiration, while translation indicates mitochondrial protein synthesis; repair and genome maintenance terms (even if older/obsolete) further support a mitochondrial genome maintenance theme, with apoptosis and tumor-cell response reflecting mitochondria-related cell death signaling. Vitamin E biosynthesis may relate to oxidative stress context within mitochondria, reinforcing the overall mitochondrial functional theme.","confidence":"High","size":16,"edges":120,"triangles":560,"max_degree":15,"top_function":null,"members":[{"accession":"XP_019330760.1","go_terms":["GO:0006123"]},{"accession":"XP_719168.2","go_terms":[]},{"accession":"XP_721455.2","go_terms":["GO:0000002","GO:0000725","GO:0036297","GO:0000733"]},{"accession":"XP_722589.1","go_terms":[]},{"accession":"XP_721562.1","go_terms":["GO:0006915"]},{"accession":"XP_709941.2","go_terms":["GO:0036265","GO:0006718","GO:0035572","GO:0035573","GO:0001887","GO:0014075","GO:0002347","GO:0070555","GO:0036068","GO:0018012","GO:0018013","GO:0006972","GO:0042220","GO:0002098","GO:0019505","GO:0035902","GO:0006370","GO:0009877","GO:0046690","GO:1901052","GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0042372","GO:0009234","GO:0009060","GO:0031167","GO:0018364","GO:0018026","GO:0018027","GO:0006596","GO:0000154"]},{"accession":"XP_711544.1","go_terms":["GO:1904960","GO:0033132","GO:0008535"]},{"accession":"XP_713785.1","go_terms":["GO:0033617","GO:0090351","GO:0032981","GO:0030150"]},{"accession":"XP_714455.1","go_terms":["GO:0061458","GO:0070584","GO:0010259","GO:0072358","GO:0006120"]},{"accession":"XP_714849.2","go_terms":["GO:0006414","GO:0006412"]},{"accession":"XP_721477.1","go_terms":[]},{"accession":"XP_722521.1","go_terms":["GO:0033617","GO:0006123","GO:0042776"]},{"accession":"XP_722630.2","go_terms":["GO:0034553"]},{"accession":"XP_713821.1","go_terms":[]},{"accession":"XP_715045.1","go_terms":["GO:0002143"]},{"accession":"XP_720952.1","go_terms":["GO:0006412"]}],"graph":[["XP_714455.1","XP_019330760.1",0.981],["XP_714455.1","XP_709941.2",0.985],["XP_714455.1","XP_711544.1",0.989],["XP_714455.1","XP_722521.1",0.977],["XP_714455.1","XP_722589.1",0.99],["XP_714455.1","XP_722630.2",0.981],["XP_714455.1","XP_720952.1",0.99],["XP_714455.1","XP_721455.2",0.989],["XP_714455.1","XP_721477.1",0.984],["XP_714455.1","XP_721562.1",0.987],["XP_714455.1","XP_719168.2",0.972],["XP_714455.1","XP_713785.1",0.981],["XP_714455.1","XP_713821.1",0.983],["XP_714455.1","XP_714849.2",0.989],["XP_714455.1","XP_715045.1",0.99],["XP_715045.1","XP_019330760.1",0.991],["XP_715045.1","XP_709941.2",0.973],["XP_715045.1","XP_711544.1",0.982],["XP_715045.1","XP_713785.1",0.991],["XP_715045.1","XP_713821.1",0.992],["XP_715045.1","XP_714849.2",0.991],["XP_715045.1","XP_719168.2",0.984],["XP_715045.1","XP_720952.1",0.987],["XP_715045.1","XP_721455.2",0.992],["XP_715045.1","XP_721477.1",0.984],["XP_715045.1","XP_721562.1",0.99],["XP_715045.1","XP_722521.1",0.983],["XP_715045.1","XP_722589.1",0.992],["XP_715045.1","XP_722630.2",0.98],["XP_019330760.1","XP_709941.2",0.988],["XP_019330760.1","XP_711544.1",0.988],["XP_019330760.1","XP_713785.1",0.98],["XP_019330760.1","XP_713821.1",0.984],["XP_019330760.1","XP_714849.2",0.99],["XP_019330760.1","XP_719168.2",0.99],["XP_019330760.1","XP_720952.1",0.984],["XP_019330760.1","XP_721455.2",0.989],["XP_019330760.1","XP_721477.1",0.96],["XP_019330760.1","XP_721562.1",0.986],["XP_019330760.1","XP_722521.1",0.941],["XP_019330760.1","XP_722589.1",0.989],["XP_019330760.1","XP_722630.2",0.985],["XP_721455.2","XP_709941.2",0.992],["XP_721455.2","XP_711544.1",0.992],["XP_721455.2","XP_713785.1",0.99],["XP_721455.2","XP_713821.1",0.983],["XP_721455.2","XP_714849.2",0.991],["XP_721455.2","XP_719168.2",0.987],["XP_721455.2","XP_720952.1",0.988],["XP_721455.2","XP_721477.1",0.988],["XP_721455.2","XP_721562.1",0.99],["XP_721455.2","XP_722521.1",0.969],["XP_721455.2","XP_722589.1",0.985],["XP_721455.2","XP_722630.2",0.975],["XP_714849.2","XP_709941.2",0.991],["XP_714849.2","XP_711544.1",0.988],["XP_714849.2","XP_713785.1",0.991],["XP_714849.2","XP_713821.1",0.991],["XP_714849.2","XP_719168.2",0.991],["XP_714849.2","XP_720952.1",0.992],["XP_714849.2","XP_721477.1",0.985],["XP_714849.2","XP_721562.1",0.99],["XP_714849.2","XP_722521.1",0.988],["XP_714849.2","XP_722589.1",0.983],["XP_714849.2","XP_722630.2",0.981],["XP_709941.2","XP_711544.1",0.992],["XP_709941.2","XP_713785.1",0.991],["XP_709941.2","XP_713821.1",0.99],["XP_709941.2","XP_719168.2",0.98],["XP_709941.2","XP_720952.1",0.991],["XP_709941.2","XP_721477.1",0.985],["XP_709941.2","XP_721562.1",0.987],["XP_709941.2","XP_722521.1",0.98],["XP_709941.2","XP_722589.1",0.99],["XP_709941.2","XP_722630.2",0.987],["XP_722630.2","XP_711544.1",0.977],["XP_722630.2","XP_713785.1",0.989],["XP_722630.2","XP_713821.1",0.988],["XP_722630.2","XP_719168.2",0.987],["XP_722630.2","XP_720952.1",0.988],["XP_722630.2","XP_721477.1",0.977],["XP_722630.2","XP_721562.1",0.986],["XP_722630.2","XP_722521.1",0.973],["XP_722630.2","XP_722589.1",0.98],["XP_713821.1","XP_711544.1",0.988],["XP_713821.1","XP_722521.1",0.98],["XP_713821.1","XP_722589.1",0.991],["XP_713821.1","XP_720952.1",0.991],["XP_713821.1","XP_721477.1",0.98],["XP_713821.1","XP_721562.1",0.989],["XP_713821.1","XP_719168.2",0.981],["XP_713821.1","XP_713785.1",0.98],["XP_722521.1","XP_711544.1",0.96],["XP_722521.1","XP_713785.1",0.965],["XP_722521.1","XP_719168.2",0.989],["XP_722521.1","XP_720952.1",0.971],["XP_722521.1","XP_721477.1",0.971],["XP_722521.1","XP_721562.1",0.975],["XP_722521.1","XP_722589.1",0.98],["XP_719168.2","XP_711544.1",0.987],["XP_719168.2","XP_713785.1",0.981],["XP_719168.2","XP_722589.1",0.992],["XP_719168.2","XP_720952.1",0.989],["XP_719168.2","XP_721477.1",0.972],["XP_719168.2","XP_721562.1",0.99],["XP_721477.1","XP_711544.1",0.988],["XP_721477.1","XP_713785.1",0.98],["XP_721477.1","XP_720952.1",0.986],["XP_721477.1","XP_721562.1",0.98],["XP_721477.1","XP_722589.1",0.976],["XP_722589.1","XP_711544.1",0.988],["XP_722589.1","XP_713785.1",0.989],["XP_722589.1","XP_720952.1",0.992],["XP_722589.1","XP_721562.1",0.99],["XP_713785.1","XP_711544.1",0.982],["XP_713785.1","XP_720952.1",0.988],["XP_713785.1","XP_721562.1",0.986],["XP_720952.1","XP_711544.1",0.985],["XP_720952.1","XP_721562.1",0.99],["XP_711544.1","XP_721562.1",0.99]],"all_go_terms":{"GO:0006123":2,"GO:0036297":1,"GO:0000725":1,"GO:0000002":1,"GO:0000733":1,"GO:0006915":1,"GO:0002347":1,"GO:0010189":1,"GO:0036068":1,"GO:0009236":1,"GO:0017000":1,"GO:0016126":1,"GO:0006744":1,"GO:0090398":1,"GO:0006596":1,"GO:0018013":1,"GO:0018012":1,"GO:0070476":1,"GO:0001300":1,"GO:0000154":1,"GO:0009877":1,"GO:0035573":1,"GO:0042220":1,"GO:0000056":1,"GO:0046690":1,"GO:0016049":1,"GO:0035690":1,"GO:0001887":1,"GO:0042372":1,"GO:0002098":1,"GO:0043985":1,"GO:0018026":1,"GO:0030488":1,"GO:0006656":1,"GO:0035572":1,"GO:0006370":1,"GO:0009060":1,"GO:0031167":1,"GO:0035902":1,"GO:0070555":1,"GO:1901052":1,"GO:0018364":1,"GO:0006718":1,"GO:0018027":1,"GO:0036265":1,"GO:0014075":1,"GO:0019505":1,"GO:0019919":1,"GO:0009102":1,"GO:0030961":1,"GO:0009234":1,"GO:0006972":1,"GO:1904960":1,"GO:0008535":1,"GO:0033132":1,"GO:0030150":1,"GO:0032981":1,"GO:0033617":2,"GO:0090351":1,"GO:0070584":1,"GO:0072358":1,"GO:0010259":1,"GO:0006120":1,"GO:0061458":1,"GO:0006412":2,"GO:0006414":1,"GO:0042776":1,"GO:0034553":1,"GO:0002143":1},"recipe_readded":[]}