{"hash":"836214209392794013","title":"PKC signaling and ECM remodeling","description":"Proteins in this cluster are linked by signaling and regulatory processes that govern adhesion and extracellular matrix dynamics, highlighted by PKC signaling, regulation of protease activity, and extracellular matrix disassembly, with additional support from regulation of adhesion molecule production. While some terms seem tangential (developmental or obsolete processes), the dominant theme is signaling-driven control of cell\u2013matrix interactions and proteolytic remodeling.","confidence":"Medium","size":3,"edges":3,"triangles":1,"max_degree":2,"top_function":null,"members":[{"accession":"XP_001454139.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_001454225.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861","GO:0050852","GO:0006851","GO:0034982","GO:0042776","GO:0035710"]},{"accession":"XP_001457863.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]}],"graph":[["XP_001454225.1","XP_001454139.1",0.949],["XP_001454225.1","XP_001457863.1",0.947],["XP_001454139.1","XP_001457863.1",0.958]],"all_go_terms":{"GO:0045541":3,"GO:0052547":3,"GO:0070528":3,"GO:0022617":3,"GO:0060355":3,"GO:0030433":3,"GO:1903905":3,"GO:0072249":3,"GO:0070584":3,"GO:0001302":3,"GO:0007007":3,"GO:0032226":3,"GO:1901585":3,"GO:1900210":3,"GO:0032933":3,"GO:1903044":3,"GO:0045861":3,"GO:0032623":3,"GO:0090297":3,"GO:0000001":3,"GO:0034141":3,"GO:0010918":3,"GO:1990046":3,"GO:2000049":3,"GO:0010876":3,"GO:0007588":3,"GO:0035710":1,"GO:0050852":1,"GO:0034982":1,"GO:0042776":1,"GO:0006851":1},"recipe_readded":[]}