{"hash":"811127614382531698","title":"Transcription Regulation and Endosomal Trafficking","description":"The cluster shows enrichment for chromatin modification and transcription regulation (histone methylation, transcription control) together with membrane trafficking (receptor recycling, endosome size) and signaling pathways (Rho signaling, NF-kappaB, synaptic transmission). This pattern suggests a module coordinating signaling events with gene expression via trafficking and chromatin regulation, rather than a single, discrete pathway.","confidence":"Medium","size":22,"edges":0,"triangles":0,"max_degree":0,"top_function":"regulation of DNA-templated transcription","members":[{"accession":"XP_001431458.1","go_terms":["GO:0030218","GO:0006309"]},{"accession":"XP_001449166.1","go_terms":[]},{"accession":"XP_001456101.1","go_terms":["GO:0007249"]},{"accession":"XP_001430188.1","go_terms":["GO:0051036","GO:0034968","GO:0006355","GO:0060316","GO:0035023","GO:0001881","GO:0035249"]},{"accession":"XP_001461950.1","go_terms":["GO:0051036","GO:0034968","GO:0006355","GO:0060316","GO:0035023","GO:0001881","GO:0035249"]},{"accession":"XP_001432299.1","go_terms":[]},{"accession":"XP_001432950.1","go_terms":[]},{"accession":"XP_001439622.1","go_terms":[]},{"accession":"XP_001453372.1","go_terms":[]},{"accession":"XP_001462531.1","go_terms":["GO:0007039","GO:0006879","GO:0042135","GO:0035609","GO:0017186","GO:0098707","GO:0006760","GO:0006898","GO:0010081","GO:0033572","GO:0019878","GO:0019877","GO:0006526","GO:0043171","GO:0009442","GO:0010136","GO:0009089","GO:0006508","GO:0006144"]},{"accession":"XP_001459788.1","go_terms":[]},{"accession":"XP_001424286.1","go_terms":[]},{"accession":"XP_001426304.1","go_terms":[]},{"accession":"XP_001427518.1","go_terms":[]},{"accession":"XP_001429961.1","go_terms":["GO:0051036","GO:0034968","GO:0006355","GO:0060316","GO:0035023","GO:0001881","GO:0035249"]},{"accession":"XP_001434759.1","go_terms":["GO:0051036","GO:0034968","GO:0006355","GO:0060316","GO:0035023","GO:0001881","GO:0035249"]},{"accession":"XP_001435638.1","go_terms":[]},{"accession":"XP_001447303.1","go_terms":["GO:0051036","GO:0034968","GO:0006355","GO:0060316","GO:0035023","GO:0001881","GO:0035249"]},{"accession":"XP_001449910.1","go_terms":["GO:0051036","GO:0034968","GO:0006355","GO:0060316","GO:0035023","GO:0001881","GO:0035249"]},{"accession":"XP_001453449.1","go_terms":[]},{"accession":"XP_001462283.1","go_terms":[]},{"accession":"XP_001425364.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0030218":1,"GO:0006309":1,"GO:0007249":1,"GO:0034968":6,"GO:0001881":6,"GO:0006355":6,"GO:0051036":6,"GO:0035023":6,"GO:0035249":6,"GO:0060316":6,"GO:0010081":1,"GO:0007039":1,"GO:0019878":1,"GO:0017186":1,"GO:0042135":1,"GO:0033572":1,"GO:0043171":1,"GO:0006760":1,"GO:0006879":1,"GO:0006508":1,"GO:0019877":1,"GO:0006898":1,"GO:0010136":1,"GO:0009089":1,"GO:0006144":1,"GO:0009442":1,"GO:0098707":1,"GO:0035609":1,"GO:0006526":1},"recipe_readded":["XP_001456336.1","XP_001445340.1","XP_001444478.1","XP_001459727.1"]}