{"hash":"486582712804391780","title":"Membrane proteolysis and signaling regulation","description":"The top GO terms point to proteolytic processing of membrane proteins (ectodomain and intramembrane proteolysis, autoproteolysis), with additional signals related to signaling pathways (calcineurin-NFAT, cGMP) and physiological regulation (immune response, renin-angiotensin). This suggests a cohesive theme around membrane-protein cleavage modulating downstream signaling and regulatory processes.","confidence":"Medium","size":9,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_001456019.1","go_terms":["GO:0050776","GO:1904211","GO:0051533","GO:0006509","GO:0070886","GO:0031293"]},{"accession":"XP_001446479.1","go_terms":[]},{"accession":"XP_001438596.1","go_terms":["GO:0030163","GO:0006508","GO:0045493","GO:0009627","GO:0002803","GO:0007586","GO:0019886","GO:0002018","GO:0016540","GO:0001823","GO:0002003","GO:0033619","GO:0070305","GO:0042985","GO:0042756","GO:0002016","GO:0050435"]},{"accession":"XP_001430680.1","go_terms":[]},{"accession":"XP_001450592.1","go_terms":["GO:0050766","GO:0006909","GO:0060434","GO:0061548","GO:0048702","GO:0031076","GO:0006910","GO:0060348","GO:1901621","GO:0060831","GO:0060041","GO:0050908","GO:0097500","GO:1903546","GO:0045494","GO:0021914"]},{"accession":"XP_001436194.1","go_terms":[]},{"accession":"XP_001441491.1","go_terms":["GO:0016255","GO:0045313"]},{"accession":"XP_001446511.1","go_terms":[]},{"accession":"XP_001441717.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0051533":1,"GO:0070886":1,"GO:0006509":1,"GO:1904211":1,"GO:0050776":1,"GO:0031293":1,"GO:0002016":1,"GO:0030163":1,"GO:0016540":1,"GO:0070305":1,"GO:0019886":1,"GO:0002003":1,"GO:0002018":1,"GO:0002803":1,"GO:0042756":1,"GO:0001823":1,"GO:0007586":1,"GO:0006508":1,"GO:0009627":1,"GO:0033619":1,"GO:0042985":1,"GO:0050435":1,"GO:0045493":1,"GO:0061548":1,"GO:0097500":1,"GO:1901621":1,"GO:0045494":1,"GO:0021914":1,"GO:0048702":1,"GO:0060348":1,"GO:0060041":1,"GO:0031076":1,"GO:0060434":1,"GO:0060831":1,"GO:0006909":1,"GO:0050908":1,"GO:0050766":1,"GO:1903546":1,"GO:0006910":1,"GO:0016255":1,"GO:0045313":1},"recipe_readded":["XP_001438920.1","XP_001424259.1","XP_001445216.1","XP_001432782.1","XP_001458996.1","XP_001439006.1","XP_001437903.1","XP_001459021.1","XP_001453093.1","XP_001459727.1","XP_001456785.1","XP_001431936.1","XP_001447644.1","XP_001443181.1","XP_001425678.1","XP_001424986.1","XP_001462044.1","XP_001438804.1","XP_001445038.1","XP_001435665.1"]}