{"hash":"2204624956951133923","title":"Innate immune signaling and inflammasome regulation","description":"The cluster centers on immune-regulatory processes, notably canonical NF-kappaB signaling, interferon production regulation, and negative regulation of the NLRP3 inflammasome, with supporting terms related to stress granule localization and protein quality control (ERAD). While some terms (skin development, muscle contraction, host-symbiont interactions) seem peripheral, the dominant Theme is innate immune signaling and cellular stress responses, suggesting a cohesive cluster around immune regulation rather than a single specific pathway.","confidence":"Medium","size":13,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_001429710.1","go_terms":[]},{"accession":"XP_001445820.1","go_terms":[]},{"accession":"XP_001458355.1","go_terms":[]},{"accession":"XP_001435530.1","go_terms":[]},{"accession":"XP_001448771.1","go_terms":["GO:0090086","GO:1902187","GO:0035372","GO:1901896","GO:0043569","GO:0046597","GO:0060776","GO:0007275","GO:0046598","GO:0003220","GO:0003151","GO:0060386","GO:0071313","GO:0071641","GO:0086029","GO:0098904","GO:0098907","GO:1900226","GO:0098910","GO:0021957","GO:0032897","GO:0045087","GO:0043123","GO:0055002","GO:0006936","GO:1901253","GO:0006914","GO:0014808","GO:0043931","GO:0030433","GO:1903608","GO:0001778","GO:0051092","GO:0051607","GO:0097050","GO:0031664","GO:0070534","GO:0005513","GO:0043588","GO:0032479"]},{"accession":"XP_001457021.1","go_terms":[]},{"accession":"XP_001457889.1","go_terms":[]},{"accession":"XP_001460261.1","go_terms":[]},{"accession":"XP_001461225.1","go_terms":[]},{"accession":"XP_001428622.1","go_terms":[]},{"accession":"XP_001438667.1","go_terms":["GO:0030500","GO:0016236","GO:0045668"]},{"accession":"XP_001439063.1","go_terms":[]},{"accession":"XP_001453721.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0043123":1,"GO:0043588":1,"GO:0030433":1,"GO:1901896":1,"GO:0006936":1,"GO:1903608":1,"GO:0032479":1,"GO:0046597":1,"GO:0097050":1,"GO:1900226":1,"GO:0032897":1,"GO:0043569":1,"GO:0098910":1,"GO:0031664":1,"GO:0035372":1,"GO:0051092":1,"GO:0043931":1,"GO:0071641":1,"GO:1901253":1,"GO:0001778":1,"GO:0051607":1,"GO:0005513":1,"GO:0098904":1,"GO:0086029":1,"GO:0006914":1,"GO:0060776":1,"GO:0071313":1,"GO:0055002":1,"GO:0045087":1,"GO:0007275":1,"GO:0098907":1,"GO:0003151":1,"GO:1902187":1,"GO:0014808":1,"GO:0003220":1,"GO:0060386":1,"GO:0021957":1,"GO:0090086":1,"GO:0070534":1,"GO:0046598":1,"GO:0030500":1,"GO:0016236":1,"GO:0045668":1},"recipe_readded":["XP_001456746.1","XP_001425492.1","XP_001461352.1","XP_001431959.1","XP_001461655.1","XP_001425317.1","XP_001457985.1","XP_001423063.1","XP_001435882.1"]}