{"hash":"1920493759228378403","title":"DNA Damage Response and SUMOylation","description":"These GO terms cluster around cellular responses to DNA damage and regulation of SUMO modification (positive regulation of protein sumoylation, autosumoylation, DNA damage\u2013related signaling and translesion synthesis). Several terms point to DNA damage response pathways (intrinsic apoptotic signaling in response to DNA damage, DNA double-strand break attachment to the nuclear envelope, regulation of DNA damage checkpoints), suggesting a cohesive theme of DDR with SUMO regulation. A few terms (vitellogenesis, membrane potential, general cell growth) are more peripheral to this core, but the dominant signal supports a DDR/SUMO-focused cluster.","confidence":"Medium","size":10,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_001427283.1","go_terms":[]},{"accession":"XP_001430685.1","go_terms":[]},{"accession":"XP_001445027.1","go_terms":[]},{"accession":"XP_001448439.1","go_terms":[]},{"accession":"XP_001434477.1","go_terms":["GO:1904333","GO:1902174","GO:1902231","GO:0010804","GO:0003007","GO:0007296","GO:0060766","GO:0016049","GO:1904290","GO:1990683","GO:0043060","GO:0045838","GO:1990466","GO:0033235","GO:0033234"]},{"accession":"XP_001455562.1","go_terms":[]},{"accession":"XP_001453222.1","go_terms":[]},{"accession":"XP_001429397.1","go_terms":[]},{"accession":"XP_001442676.1","go_terms":[]},{"accession":"XP_001428659.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0033235":1,"GO:1902231":1,"GO:1904333":1,"GO:0007296":1,"GO:1990683":1,"GO:0045838":1,"GO:1990466":1,"GO:0016049":1,"GO:1904290":1,"GO:0010804":1,"GO:0033234":1,"GO:1902174":1,"GO:0003007":1,"GO:0043060":1,"GO:0060766":1},"recipe_readded":["XP_001446593.1","XP_001428406.1","XP_001449275.1","XP_001451291.1","XP_001458961.1","XP_001435835.1","XP_001423949.1","XP_001457079.1","XP_001454613.1","XP_001430251.1","XP_001428617.1","XP_001428532.1","XP_001437200.1","XP_001428509.1","XP_001433614.1","XP_001437532.1","XP_001427108.1","XP_001431687.1","XP_001430274.1","XP_001444627.1"]}