{"hash":"1236393814155189365","title":"Actin Cytoskeleton Remodeling in Meiosis","description":"The top GO terms are dominated by actin-related processes (actin filament network formation, actin nucleation, actomyosin contractile ring assembly, regulation of cell shape), suggesting a core theme of actin cytoskeleton remodeling. Additionally, terms related to meiosis and female gamete generation (centrosome localization, chromosome movement toward spindle poles) point to a role for actin dynamics during meiotic progression in oocytes. Some terms (histamine response, synaptic depression) appear more peripheral, but do not overwhelm the central actin/meiosis signal. Overall, the cluster seems to reflect actin-driven cytoskeleton remodeling linked to meiosis/oocyte development.","confidence":"Medium","size":5,"edges":7,"triangles":3,"max_degree":4,"top_function":null,"members":[{"accession":"XP_001436180.1","go_terms":[]},{"accession":"XP_001441624.1","go_terms":[]},{"accession":"XP_001449252.1","go_terms":[]},{"accession":"XP_001426917.1","go_terms":["GO:0006929","GO:0007292","GO:0061164","GO:0051639","GO:0051758","GO:0070649","GO:0045010","GO:0071519","GO:2000251","GO:0010467","GO:1904171","GO:0072092","GO:0055003","GO:0051295","GO:0051660","GO:0008360","GO:0071420","GO:0060292","GO:0040038","GO:1904670"]},{"accession":"XP_001441006.1","go_terms":["GO:0030032","GO:0030036","GO:0051388","GO:0030041","GO:0051639","GO:0002625","GO:0031175","GO:0001757","GO:0032233","GO:0007121","GO:0045010","GO:1900029","GO:0051497","GO:0033504","GO:0090140","GO:0051491","GO:0035855","GO:2000402","GO:0051694","GO:2000601","GO:0044397","GO:0051016","GO:0048669","GO:1903526","GO:0072673","GO:0014003","GO:0097484","GO:0051014","GO:0030046","GO:0010592","GO:0016601","GO:0030048","GO:0031643","GO:1990416","GO:0060997"]}],"graph":[["XP_001441624.1","XP_001441006.1",0.692],["XP_001441624.1","XP_001426917.1",0.706],["XP_001436180.1","XP_001441006.1",0.751],["XP_001436180.1","XP_001426917.1",0.901],["XP_001449252.1","XP_001426917.1",0.938],["XP_001449252.1","XP_001441006.1",0.719],["XP_001441006.1","XP_001426917.1",0.911]],"all_go_terms":{"GO:0055003":1,"GO:0060292":1,"GO:0007292":1,"GO:0071519":1,"GO:0008360":1,"GO:0051758":1,"GO:0051660":1,"GO:0071420":1,"GO:0061164":1,"GO:0051295":1,"GO:1904670":1,"GO:0051639":2,"GO:0006929":1,"GO:2000251":1,"GO:0010467":1,"GO:0072092":1,"GO:1904171":1,"GO:0040038":1,"GO:0045010":2,"GO:0070649":1,"GO:0048669":1,"GO:0030036":1,"GO:0097484":1,"GO:0035855":1,"GO:0044397":1,"GO:0030046":1,"GO:1900029":1,"GO:0031643":1,"GO:0014003":1,"GO:1990416":1,"GO:0060997":1,"GO:0090140":1,"GO:0016601":1,"GO:0051694":1,"GO:1903526":1,"GO:0002625":1,"GO:2000402":1,"GO:0032233":1,"GO:0010592":1,"GO:0033504":1,"GO:0030032":1,"GO:0007121":1,"GO:0030041":1,"GO:2000601":1,"GO:0001757":1,"GO:0072673":1,"GO:0030048":1,"GO:0051014":1,"GO:0051491":1,"GO:0051497":1,"GO:0051388":1,"GO:0051016":1,"GO:0031175":1},"recipe_readded":[]}