{"hash":"449269622646180020","title":"Brush border microvilli and endomembrane organization","description":"GO terms center on intestinal apical surface structures (microvilli, terminal web, microspike assembly, microvillus length) and trafficking/endomembrane processes (endomembrane system organization, glucose absorption, antigen processing via MHC II, pinocytosis, autophagy). This pattern suggests a cluster of proteins coordinating brush border assembly and vesicular trafficking in intestinal epithelial cells, with supporting roles in nutrient uptake and immune processing. A few terms such as myelin assembly may be incidental, but the dominant theme is epithelial surface organization and endomembrane dynamics.","confidence":"High","size":20,"edges":130,"triangles":416,"max_degree":18,"top_function":null,"members":[{"accession":"XP_012199536.1","go_terms":[]},{"accession":"XP_012201048.1","go_terms":[]},{"accession":"XP_012201692.1","go_terms":["GO:0051127","GO:0048081","GO:2000189","GO:0035149","GO:0021747","GO:0046597","GO:0010004","GO:0042989","GO:0060327","GO:1990000","GO:1902896","GO:1903923","GO:1903906","GO:0071801","GO:2000394","GO:1901301","GO:0045010","GO:0035729","GO:2000012","GO:0006886","GO:1903909","GO:1903689","GO:0097284","GO:0051694","GO:2001269","GO:1902174","GO:0016236","GO:0051017","GO:0051016","GO:0051014","GO:0010975","GO:0030041","GO:0006888","GO:0061156","GO:0090527","GO:0090110","GO:0003331","GO:1903903","GO:0045654","GO:0001951","GO:0060463","GO:0003400","GO:0014891","GO:0097017","GO:0032532","GO:0060982","GO:0045714","GO:0048208","GO:0070278","GO:0060088","GO:0019886","GO:0048702","GO:0032876","GO:0080119","GO:0090178","GO:0035909"]},{"accession":"XP_012201695.1","go_terms":["GO:0007179","GO:1903358","GO:0032288","GO:0035023","GO:0071787","GO:0045053","GO:0090160","GO:0035973","GO:0007183","GO:0006622","GO:0030035","GO:0034145","GO:0034141","GO:0034058","GO:0016197","GO:0048549","GO:0046847","GO:1904562","GO:0010256"]},{"accession":"XP_012201920.1","go_terms":["GO:0043552","GO:0090207","GO:0008333","GO:0016236","GO:0000045","GO:0098779","GO:0048803","GO:0007098","GO:0035493","GO:0042149","GO:0097680","GO:0051684","GO:0016240"]},{"accession":"XP_012205970.1","go_terms":[]},{"accession":"XP_012207286.1","go_terms":["GO:0000244","GO:0008380","GO:0006397","GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_012208224.1","go_terms":[]},{"accession":"XP_012209527.1","go_terms":["GO:0070940","GO:0051209","GO:0051533","GO:0042769","GO:0006369","GO:0006378","GO:0006379","GO:0010526"]},{"accession":"XP_012209830.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0031990","GO:0060188","GO:0006607","GO:0006999","GO:0072417","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451","GO:0050847","GO:0048096","GO:0060212","GO:0035413","GO:0007289","GO:0045314","GO:0001556","GO:1901315","GO:2000623","GO:2000780","GO:0033160"]},{"accession":"XP_012212207.1","go_terms":["GO:0090234","GO:1904333","GO:0000338","GO:0060711","GO:0060712","GO:0010724","GO:0032875","GO:0016926","GO:0035562"]},{"accession":"XP_012212681.1","go_terms":[]},{"accession":"XP_012194814.1","go_terms":[]},{"accession":"XP_012197002.1","go_terms":["GO:0035855","GO:0014066","GO:0097178","GO:0072661","GO:0046854","GO:0010256","GO:0032288","GO:0031321","GO:0042070","GO:1902635","GO:0048041","GO:0010761","GO:2000786"]},{"accession":"XP_012198231.1","go_terms":[]},{"accession":"XP_012199642.1","go_terms":["GO:0033212","GO:0042167","GO:0055114","GO:0042984"]},{"accession":"XP_012201883.1","go_terms":["GO:0046786"]},{"accession":"XP_012205367.1","go_terms":["GO:0034453","GO:0043552","GO:0030593","GO:0030890","GO:0030032","GO:0045954","GO:0050853","GO:0035023","GO:0045218","GO:0090136","GO:0031175","GO:0007229","GO:0099515","GO:0031115","GO:1990735","GO:0003025","GO:2001137","GO:0009652","GO:1902896","GO:0043087","GO:0071963","GO:0021692","GO:0070649","GO:0090286","GO:1900024","GO:0051693","GO:1903033","GO:0051695","GO:0048633","GO:0016203","GO:1901018","GO:0021564","GO:0051661","GO:0014732","GO:0045214","GO:0051666","GO:0021563","GO:0030042","GO:1904825","GO:1902396","GO:0016055","GO:0001951","GO:0021873","GO:0010735","GO:1901078","GO:0086097","GO:1903475","GO:1904025","GO:1903478","GO:0032532","GO:0048734","GO:2000009","GO:0055013","GO:0030989","GO:0021629","GO:0030035","GO:0051639","GO:0090307","GO:0048041","GO:0014728","GO:0045769","GO:0000743","GO:0007026","GO:0031532","GO:0006887","GO:0048549","GO:0070493","GO:1900042","GO:0007182","GO:1902405","GO:1904706","GO:1900159","GO:1904519","GO:0014809","GO:1903477","GO:0061171","GO:0030437","GO:0007155","GO:0051764","GO:0030048","GO:0000742","GO:0019417","GO:0031448","GO:0014894","GO:0021869","GO:0071670","GO:0032458"]},{"accession":"XP_012206832.1","go_terms":["GO:0048147","GO:0042590","GO:1900426","GO:0019886"]},{"accession":"XP_012211617.1","go_terms":[]}],"graph":[["XP_012205970.1","XP_012194814.1",0.858],["XP_012205970.1","XP_012197002.1",0.686],["XP_012205970.1","XP_012199536.1",0.765],["XP_012205970.1","XP_012199642.1",0.929],["XP_012205970.1","XP_012201048.1",0.923],["XP_012205970.1","XP_012201692.1",0.86],["XP_012205970.1","XP_012201695.1",0.856],["XP_012205970.1","XP_012201920.1",0.53],["XP_012205970.1","XP_012206832.1",0.893],["XP_012205970.1","XP_012207286.1",0.894],["XP_012205970.1","XP_012208224.1",0.662],["XP_012205970.1","XP_012209527.1",0.916],["XP_012205970.1","XP_012209830.1",0.75],["XP_012205970.1","XP_012212207.1",0.795],["XP_012205970.1","XP_012212681.1",0.62],["XP_012201695.1","XP_012194814.1",0.896],["XP_012201695.1","XP_012197002.1",0.914],["XP_012201695.1","XP_012198231.1",0.942],["XP_012201695.1","XP_012199536.1",0.901],["XP_012201695.1","XP_012199642.1",0.843],["XP_012201695.1","XP_012201048.1",0.92],["XP_012201695.1","XP_012201692.1",0.867],["XP_012201695.1","XP_012201883.1",0.731],["XP_012201695.1","XP_012201920.1",0.782],["XP_012201695.1","XP_012205367.1",0.845],["XP_012201695.1","XP_012206832.1",0.976],["XP_012201695.1","XP_012207286.1",0.913],["XP_012201695.1","XP_012208224.1",0.848],["XP_012201695.1","XP_012209527.1",0.913],["XP_012201695.1","XP_012209830.1",0.916],["XP_012201695.1","XP_012211617.1",0.893],["XP_012201695.1","XP_012212207.1",0.572],["XP_012209830.1","XP_012194814.1",0.701],["XP_012209830.1","XP_012197002.1",0.921],["XP_012209830.1","XP_012198231.1",0.87],["XP_012209830.1","XP_012199536.1",0.602],["XP_012209830.1","XP_012201048.1",0.751],["XP_012209830.1","XP_012201692.1",0.889],["XP_012209830.1","XP_012201883.1",0.692],["XP_012209830.1","XP_012201920.1",0.72],["XP_012209830.1","XP_012205367.1",0.936],["XP_012209830.1","XP_012206832.1",0.943],["XP_012209830.1","XP_012207286.1",0.826],["XP_012209830.1","XP_012208224.1",0.664],["XP_012209830.1","XP_012209527.1",0.944],["XP_012209830.1","XP_012211617.1",0.948],["XP_012209830.1","XP_012212207.1",0.615],["XP_012208224.1","XP_012194814.1",0.795],["XP_012208224.1","XP_012197002.1",0.904],["XP_012208224.1","XP_012198231.1",0.873],["XP_012208224.1","XP_012199536.1",0.744],["XP_012208224.1","XP_012199642.1",0.895],["XP_012208224.1","XP_012201048.1",0.896],["XP_012208224.1","XP_012201692.1",0.602],["XP_012208224.1","XP_012201920.1",0.971],["XP_012208224.1","XP_012205367.1",0.612],["XP_012208224.1","XP_012206832.1",0.948],["XP_012208224.1","XP_012207286.1",0.672],["XP_012208224.1","XP_012209527.1",0.556],["XP_012208224.1","XP_012211617.1",0.682],["XP_012208224.1","XP_012212207.1",0.86],["XP_012201920.1","XP_012201048.1",0.622],["XP_012201920.1","XP_012201692.1",0.862],["XP_012201920.1","XP_012207286.1",0.793],["XP_012201920.1","XP_012209527.1",0.96],["XP_012201920.1","XP_012211617.1",0.663],["XP_012201920.1","XP_012212207.1",0.642],["XP_012211617.1","XP_012199536.1",0.716],["XP_012211617.1","XP_012201048.1",0.916],["XP_012211617.1","XP_012201692.1",0.738],["XP_012211617.1","XP_012207286.1",0.762],["XP_012211617.1","XP_012209527.1",0.947],["XP_012211617.1","XP_012212207.1",0.566],["XP_012211617.1","XP_012212681.1",0.893],["XP_012201692.1","XP_012194814.1",0.657],["XP_012201692.1","XP_012197002.1",0.886],["XP_012201692.1","XP_012198231.1",0.863],["XP_012201692.1","XP_012199536.1",0.772],["XP_012201692.1","XP_012199642.1",0.871],["XP_012201692.1","XP_012201048.1",0.905],["XP_012201692.1","XP_012205367.1",0.798],["XP_012201692.1","XP_012206832.1",0.898],["XP_012201692.1","XP_012207286.1",0.917],["XP_012201692.1","XP_012209527.1",0.827],["XP_012201692.1","XP_012212207.1",0.584],["XP_012201692.1","XP_012212681.1",0.525],["XP_012201883.1","XP_012201048.1",0.63],["XP_012201883.1","XP_012207286.1",0.744],["XP_012201883.1","XP_012209527.1",0.573],["XP_012201883.1","XP_012212207.1",0.544],["XP_012201883.1","XP_012212681.1",0.633],["XP_012206832.1","XP_012199536.1",0.916],["XP_012206832.1","XP_012201048.1",0.71],["XP_012206832.1","XP_012207286.1",0.938],["XP_012206832.1","XP_012209527.1",0.962],["XP_012206832.1","XP_012212681.1",0.972],["XP_012201048.1","XP_012194814.1",0.774],["XP_012201048.1","XP_012197002.1",0.779],["XP_012201048.1","XP_012198231.1",0.945],["XP_012201048.1","XP_012199536.1",0.895],["XP_012201048.1","XP_012205367.1",0.917],["XP_012201048.1","XP_012212681.1",0.73],["XP_012201048.1","XP_012209527.1",0.888],["XP_012201048.1","XP_012207286.1",0.717],["XP_012205367.1","XP_012212207.1",0.64],["XP_012205367.1","XP_012209527.1",0.524],["XP_012205367.1","XP_012207286.1",0.907],["XP_012194814.1","XP_012199536.1",0.732],["XP_012194814.1","XP_012207286.1",0.688],["XP_012194814.1","XP_012209527.1",0.953],["XP_012194814.1","XP_012212681.1",0.974],["XP_012199536.1","XP_012197002.1",0.848],["XP_012199536.1","XP_012198231.1",0.612],["XP_012199536.1","XP_012199642.1",0.647],["XP_012199536.1","XP_012207286.1",0.867],["XP_012199536.1","XP_012209527.1",0.895],["XP_012199536.1","XP_012212207.1",0.676],["XP_012198231.1","XP_012207286.1",0.665],["XP_012198231.1","XP_012209527.1",0.904],["XP_012198231.1","XP_012212207.1",0.539],["XP_012207286.1","XP_012197002.1",0.691],["XP_012207286.1","XP_012199642.1",0.781],["XP_012207286.1","XP_012212207.1",0.725],["XP_012207286.1","XP_012209527.1",0.881],["XP_012209527.1","XP_012197002.1",0.963],["XP_012209527.1","XP_012199642.1",0.863],["XP_012209527.1","XP_012212207.1",0.827],["XP_012197002.1","XP_012212681.1",0.767],["XP_012212207.1","XP_012212681.1",0.738],["XP_012212681.1","XP_012199642.1",0.955]],"all_go_terms":{"GO:0048081":1,"GO:0014891":1,"GO:0051014":1,"GO:0046597":1,"GO:0090110":1,"GO:0071801":1,"GO:0090178":1,"GO:0045010":1,"GO:1990000":1,"GO:1902896":2,"GO:2000394":1,"GO:2000012":1,"GO:0006888":1,"GO:0097017":1,"GO:0032876":1,"GO:2000189":1,"GO:0001951":2,"GO:1901301":1,"GO:1902174":1,"GO:0035149":1,"GO:1903923":1,"GO:1903906":1,"GO:0048208":1,"GO:0060982":1,"GO:1903903":1,"GO:0070278":1,"GO:0016236":2,"GO:0051017":1,"GO:0035729":1,"GO:0021747":1,"GO:0003400":1,"GO:0051694":1,"GO:0045654":1,"GO:0060088":1,"GO:1903689":1,"GO:0006886":1,"GO:0097284":1,"GO:0051127":1,"GO:0003331":1,"GO:0010975":1,"GO:0045714":1,"GO:0090527":1,"GO:1903909":1,"GO:0061156":1,"GO:0060463":1,"GO:2001269":1,"GO:0010004":1,"GO:0048702":1,"GO:0051016":1,"GO:0060327":1,"GO:0030041":1,"GO:0032532":2,"GO:0035909":1,"GO:0019886":2,"GO:0042989":1,"GO:0080119":1,"GO:0007183":1,"GO:0071787":1,"GO:0045053":1,"GO:0010256":2,"GO:0030035":2,"GO:0046847":1,"GO:0035973":1,"GO:0090160":1,"GO:0006622":1,"GO:0034058":1,"GO:0032288":2,"GO:0034145":1,"GO:0007179":1,"GO:0048549":2,"GO:1904562":1,"GO:0016197":1,"GO:1903358":1,"GO:0035023":2,"GO:0034141":1,"GO:0043552":2,"GO:0097680":1,"GO:0007098":1,"GO:0090207":1,"GO:0042149":1,"GO:0035493":1,"GO:0000045":1,"GO:0051684":1,"GO:0008333":1,"GO:0048803":1,"GO:0098779":1,"GO:0016240":1,"GO:0008380":1,"GO:0016556":2,"GO:0031047":2,"GO:1902625":2,"GO:0006376":2,"GO:0000381":2,"GO:0048025":2,"GO:0002188":2,"GO:0000380":2,"GO:0006378":3,"GO:0060211":2,"GO:1900363":2,"GO:0034462":2,"GO:0000244":1,"GO:0048255":2,"GO:0045292":2,"GO:0035278":2,"GO:0097010":2,"GO:0010610":2,"GO:0001825":2,"GO:0075525":2,"GO:0075522":2,"GO:0001731":2,"GO:1903586":2,"GO:0048026":2,"GO:0006397":1,"GO:0006446":2,"GO:0006406":2,"GO:1905663":2,"GO:1901407":2,"GO:0051209":1,"GO:0042769":1,"GO:0070940":1,"GO:0051533":1,"GO:0010526":1,"GO:0006379":1,"GO:0006369":1,"GO:0031990":1,"GO:0032869":1,"GO:0048096":1,"GO:1900248":1,"GO:0071230":1,"GO:0060213":1,"GO:0035413":1,"GO:1901315":1,"GO:0006999":1,"GO:0072417":1,"GO:0050847":1,"GO:0001556":1,"GO:0046011":1,"GO:0008069":1,"GO:1900365":1,"GO:0045451":1,"GO:0006607":1,"GO:0002931":1,"GO:0007310":1,"GO:2000623":1,"GO:0071456":1,"GO:0007289":1,"GO:0045314":1,"GO:0033160":1,"GO:0060212":1,"GO:0060188":1,"GO:0061158":1,"GO:2000780":1,"GO:0035562":1,"GO:1904333":1,"GO:0000338":1,"GO:0060711":1,"GO:0016926":1,"GO:0090234":1,"GO:0032875":1,"GO:0010724":1,"GO:0060712":1,"GO:0035855":1,"GO:0031321":1,"GO:0097178":1,"GO:2000786":1,"GO:0042070":1,"GO:0046854":1,"GO:1902635":1,"GO:0010761":1,"GO:0048041":2,"GO:0014066":1,"GO:0072661":1,"GO:0055114":1,"GO:0042167":1,"GO:0033212":1,"GO:0042984":1,"GO:0046786":1,"GO:0021869":1,"GO:1903478":1,"GO:0071670":1,"GO:0030042":1,"GO:0051693":1,"GO:0016203":1,"GO:0014809":1,"GO:0071963":1,"GO:1901018":1,"GO:0045214":1,"GO:1903477":1,"GO:0021629":1,"GO:0030032":1,"GO:1900042":1,"GO:0090286":1,"GO:0021563":1,"GO:0055013":1,"GO:1990735":1,"GO:0070649":1,"GO:0048633":1,"GO:0003025":1,"GO:0030593":1,"GO:0032458":1,"GO:1900159":1,"GO:0051639":1,"GO:0048734":1,"GO:0086097":1,"GO:0090136":1,"GO:0010735":1,"GO:2000009":1,"GO:0014732":1,"GO:2001137":1,"GO:0030048":1,"GO:0007182":1,"GO:0050853":1,"GO:0051764":1,"GO:0030890":1,"GO:1904706":1,"GO:0007229":1,"GO:0034453":1,"GO:0045218":1,"GO:0030437":1,"GO:0006887":1,"GO:1903475":1,"GO:0021692":1,"GO:0045954":1,"GO:0009652":1,"GO:0014894":1,"GO:0021873":1,"GO:0031448":1,"GO:0007155":1,"GO:1903033":1,"GO:0099515":1,"GO:0031532":1,"GO:0070493":1,"GO:0014728":1,"GO:0051695":1,"GO:1904825":1,"GO:0051666":1,"GO:0030989":1,"GO:0045769":1,"GO:1904025":1,"GO:1902396":1,"GO:1904519":1,"GO:0043087":1,"GO:0016055":1,"GO:0000743":1,"GO:1900024":1,"GO:0051661":1,"GO:0061171":1,"GO:0021564":1,"GO:0090307":1,"GO:0031175":1,"GO:1902405":1,"GO:0031115":1,"GO:1901078":1,"GO:0007026":1,"GO:0019417":1,"GO:0000742":1,"GO:0048147":1,"GO:0042590":1,"GO:1900426":1},"recipe_readded":[]}