{"hash":"1312258809253453649","title":"Central carbon metabolism and amino acid catabolism","description":"The top GO terms are dominated by central metabolism: glycolysis, TCA cycle, pyruvate biosynthesis, and amino acid catabolic/ biosynthetic processes (L-alanine, L-serine, L-kynurenine). Although Notch signaling appears among the terms, it seems peripheral to the core metabolic theme that ties the majority of proteins in this cluster to energy production and amino-acid turnover. Therefore, the cluster is best described as central carbon metabolism and amino acid catabolism.","confidence":"Medium","size":29,"edges":405,"triangles":3627,"max_degree":28,"top_function":"DNA-templated transcription","members":[{"accession":"XP_012194364.1","go_terms":["GO:0072756","GO:0009228","GO:0072747","GO:0046166","GO:0061732","GO:0006098","GO:0006096","GO:0055114","GO:0052865","GO:0005999","GO:0040008","GO:0010510","GO:0006006","GO:0016114","GO:0061034","GO:0006099"]},{"accession":"XP_012194695.1","go_terms":["GO:0009249","GO:0019464"]},{"accession":"XP_012195477.1","go_terms":["GO:2001234","GO:0071269","GO:1904831","GO:0051092","GO:0019450","GO:0070814","GO:0019346","GO:0019343","GO:0018272","GO:0044524","GO:0019279","GO:0043123","GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265","GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_012197856.1","go_terms":["GO:0043617","GO:0006086","GO:0000002","GO:0006099","GO:0006103","GO:0033512","GO:0006096","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_012198182.1","go_terms":["GO:0072756","GO:0009228","GO:0072747","GO:0046166","GO:0061732","GO:0006098","GO:0006096","GO:0055114","GO:0052865","GO:0005999","GO:0040008","GO:0010510","GO:0006006","GO:0016114","GO:0061034","GO:0006099"]},{"accession":"XP_012198838.1","go_terms":["GO:0043617","GO:0006086","GO:0000002","GO:0006099","GO:0006103","GO:0033512","GO:0006096","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_012199465.1","go_terms":["GO:0044268","GO:0019552","GO:0042759","GO:2001295","GO:0006633"]},{"accession":"XP_012200761.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0014823","GO:0042493","GO:0042413","GO:0046676","GO:0032868","GO:0006574","GO:0019521","GO:0006096","GO:0045454"]},{"accession":"XP_012201554.1","go_terms":["GO:0070179","GO:0019499","GO:0009310","GO:0046360","GO:0043278","GO:0018871","GO:0043418","GO:0006565","GO:0006535","GO:0019295","GO:0000162","GO:0070814","GO:0042866","GO:0019346","GO:0019343","GO:0009088","GO:0070689","GO:0009097","GO:0006566"]},{"accession":"XP_012203172.1","go_terms":["GO:0033512","GO:0006814","GO:0006099","GO:2001295","GO:0042759","GO:0006096","GO:0006086","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_012203299.1","go_terms":["GO:1904482","GO:0034340","GO:0035999","GO:0009113","GO:0046655","GO:0006565","GO:0006564","GO:0006231","GO:0051289","GO:0019264","GO:0017148","GO:0032259","GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_012205348.1","go_terms":["GO:0030242","GO:0006810","GO:0050826","GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_012206110.1","go_terms":["GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265"]},{"accession":"XP_012208150.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_012197220.1","go_terms":["GO:0006556","GO:0006730","GO:0009087","GO:0033353"]},{"accession":"XP_012197857.1","go_terms":["GO:0033512","GO:0006814","GO:0006099","GO:2001295","GO:0042759","GO:0006096","GO:0006086","GO:0006552","GO:0006213","GO:0006094","GO:0009249","GO:0019464"]},{"accession":"XP_012200682.1","go_terms":["GO:2001234","GO:0071269","GO:1904831","GO:0051092","GO:0019450","GO:0070814","GO:0019346","GO:0019343","GO:0018272","GO:0044524","GO:0019279","GO:0043123","GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265","GO:0009243","GO:0017000","GO:0009246","GO:0009245","GO:0071555","GO:0046677","GO:0009103"]},{"accession":"XP_012207799.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065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