{"hash":"737079370008231763","title":"ER stress and protein folding","description":"The terms center on endoplasmic reticulum functions: protein folding in the ER, ER unfolded protein response, and ER stress\u2013related apoptotic signaling; chaperone regulation of autophagy also ties to ER quality control. Some terms such as insulin processing and extracellular matrix organization reflect secretory pathway involvement. A few annotations (phytochelatin biosynthesis) appear as noise. Overall, the cluster seems to represent ER-associated protein maturation and stress response.","confidence":"Medium","size":7,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_002293468.1","go_terms":["GO:1904715","GO:0046938","GO:0006508","GO:0043085"]},{"accession":"XP_002291488.1","go_terms":[]},{"accession":"XP_002295177.1","go_terms":[]},{"accession":"XP_002289116.1","go_terms":[]},{"accession":"XP_002286191.1","go_terms":[]},{"accession":"XP_002288155.1","go_terms":[]},{"accession":"XP_002290855.1","go_terms":["GO:0010260","GO:0030968","GO:0070059","GO:0051085","GO:0019471","GO:0050873","GO:0051209","GO:0022417","GO:0030198","GO:0030070","GO:0034975"]}],"graph":[],"all_go_terms":{"GO:1904715":1,"GO:0043085":1,"GO:0006508":1,"GO:0046938":1,"GO:0070059":1,"GO:0030198":1,"GO:0034975":1,"GO:0030968":1,"GO:0030070":1,"GO:0022417":1,"GO:0050873":1,"GO:0051209":1,"GO:0019471":1,"GO:0051085":1,"GO:0010260":1},"recipe_readded":["XP_002296663.1","XP_002293451.1","XP_002297281.1","XP_002293082.1","XP_002289696.1","XP_002297435.1","XP_002286414.1","XP_002296579.1","XP_002291099.1","XP_002293012.1","XP_002291304.1","XP_002290441.1","XP_002289419.1","XP_002290604.1","XP_002290129.1","XP_002292057.1","XP_002292357.1","XP_002294199.1","XP_002293141.1","XP_002286877.1"]}