{"hash":"1807383733376508966","title":"Mitochondrial Protein Import and Complex IV Assembly","description":"The cluster is strongly enriched for mitochondrial-centric processes: import of proteins into the mitochondrial matrix, assembly of the respiratory chain complex IV, and related calcium handling within mitochondria, plus signals of nitrosative stress response and other mitochondrial metabolic activities. These shared themes point to a cohesive mitochondrion-focused module, coordinating protein import with assembly of respiratory components and calcium/metabolic regulation.","confidence":"High","size":19,"edges":169,"triangles":936,"max_degree":18,"top_function":null,"members":[{"accession":"XP_006089365.1","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0010205","GO:0010206","GO:0010304","GO:0030150","GO:0006515","GO:0060013","GO:0030163"]},{"accession":"XP_006082432.2","go_terms":["GO:0031426","GO:0048507","GO:0010239","GO:0080163","GO:0006744","GO:0043086"]},{"accession":"XP_006103735.1","go_terms":["GO:0006412"]},{"accession":"XP_006085414.1","go_terms":["GO:0006412"]},{"accession":"XP_006097325.1","go_terms":["GO:0030218","GO:0051882","GO:0032780","GO:1904925","GO:1903578","GO:1903214","GO:1901030","GO:0006783","GO:0001937"]},{"accession":"XP_006098522.1","go_terms":["GO:0033617","GO:0036444","GO:0051561"]},{"accession":"XP_006102269.1","go_terms":["GO:0070131","GO:0010082"]},{"accession":"XP_006107148.1","go_terms":[]},{"accession":"XP_006109297.1","go_terms":["GO:0006412"]},{"accession":"XP_014303178.1","go_terms":["GO:0006646","GO:0010636","GO:0006656","GO:0016540","GO:0010954"]},{"accession":"XP_014306040.1","go_terms":["GO:0014740","GO:0032770","GO:0009636","GO:0071500","GO:0045429","GO:0009437","GO:0010124","GO:0045880","GO:1901206","GO:0000103","GO:0006809","GO:0060192","GO:0014806","GO:0071372","GO:1901300","GO:0071375","GO:0044205","GO:0098924","GO:0032332","GO:0072604","GO:0045542","GO:0018393","GO:0031284","GO:0072606","GO:0009812","GO:0090346","GO:0007584","GO:0018119","GO:0006814","GO:0046210","GO:0032310","GO:0019395","GO:0042128","GO:0070988","GO:1904042","GO:0090031","GO:0043602","GO:0042493","GO:0070814","GO:0043154","GO:0019344","GO:0006695","GO:0006696","GO:0003420","GO:0042554","GO:0051591","GO:1902177","GO:0050665","GO:0009590","GO:0048855","GO:0006590","GO:1904845","GO:0048840","GO:0072592","GO:0010467","GO:0045730","GO:1990451","GO:0003081","GO:0008365","GO:0015677","GO:0045726","GO:0045453"]},{"accession":"XP_014319582.1","go_terms":["GO:0033617","GO:0036444","GO:0051561"]},{"accession":"XP_006083727.1","go_terms":["GO:0014740","GO:0032770","GO:0009636","GO:0071500","GO:0045429","GO:0009437","GO:0010124","GO:0045880","GO:1901206","GO:0000103","GO:0006809","GO:0060192","GO:0014806","GO:0071372","GO:1901300","GO:0071375","GO:0044205","GO:0098924","GO:0032332","GO:0072604","GO:0045542","GO:0018393","GO:0031284","GO:0072606","GO:0009812","GO:0090346","GO:0007584","GO:0018119","GO:0006814","GO:0046210","GO:0032310","GO:0019395","GO:0042128","GO:0070988","GO:1904042","GO:0090031","GO:0043602","GO:0042493","GO:0070814","GO:0043154","GO:0019344","GO:0006695","GO:0006696","GO:0003420","GO:0042554","GO:0051591","GO:1902177","GO:0050665","GO:0009590","GO:0048855","GO:0006590","GO:1904845","GO:0048840","GO:0072592","GO:0010467","GO:0045730","GO:1990451","GO:0003081","GO:0008365","GO:0015677","GO:0045726","GO:0045453"]},{"accession":"XP_006086831.1","go_terms":[]},{"accession":"XP_006090849.1","go_terms":["GO:0033617","GO:0090351","GO:0032981","GO:0030150"]},{"accession":"XP_006085573.1","go_terms":[]},{"accession":"XP_006088139.1","go_terms":[]},{"accession":"XP_006106480.1","go_terms":["GO:0070584","GO:0050881","GO:0019216","GO:0031413","GO:0050905"]},{"accession":"XP_014316749.1","go_terms":["GO:0070124","GO:0006412"]}],"graph":[["XP_006085414.1","XP_006082432.2",0.935],["XP_006085414.1","XP_006083727.1",0.984],["XP_006085414.1","XP_006085573.1",0.698],["XP_006085414.1","XP_006086831.1",0.985],["XP_006085414.1","XP_006088139.1",0.911],["XP_006085414.1","XP_006089365.1",0.923],["XP_006085414.1","XP_006090849.1",0.974],["XP_006085414.1","XP_006097325.1",0.953],["XP_006085414.1","XP_006098522.1",0.833],["XP_006085414.1","XP_006102269.1",0.987],["XP_006085414.1","XP_006106480.1",0.961],["XP_006085414.1","XP_006107148.1",0.934],["XP_006085414.1","XP_014303178.1",0.96],["XP_006085414.1","XP_014306040.1",0.961],["XP_006085414.1","XP_014316749.1",0.681],["XP_006085414.1","XP_014319582.1",0.931],["XP_014303178.1","XP_014306040.1",0.975],["XP_014303178.1","XP_014316749.1",0.912],["XP_014303178.1","XP_014319582.1",0.95],["XP_014303178.1","XP_006082432.2",0.985],["XP_014303178.1","XP_006083727.1",0.977],["XP_014303178.1","XP_006085573.1",0.986],["XP_014303178.1","XP_006086831.1",0.956],["XP_014303178.1","XP_006088139.1",0.964],["XP_014303178.1","XP_006089365.1",0.978],["XP_014303178.1","XP_006090849.1",0.97],["XP_014303178.1","XP_006097325.1",0.956],["XP_014303178.1","XP_006098522.1",0.953],["XP_014303178.1","XP_006102269.1",0.972],["XP_014303178.1","XP_006103735.1",0.928],["XP_014303178.1","XP_006106480.1",0.986],["XP_014303178.1","XP_006107148.1",0.983],["XP_014303178.1","XP_006109297.1",0.978],["XP_006098522.1","XP_006082432.2",0.866],["XP_006098522.1","XP_006083727.1",0.86],["XP_006098522.1","XP_006085573.1",0.857],["XP_006098522.1","XP_006086831.1",0.977],["XP_006098522.1","XP_006088139.1",0.852],["XP_006098522.1","XP_006089365.1",0.961],["XP_006098522.1","XP_006090849.1",0.967],["XP_006098522.1","XP_006097325.1",0.892],["XP_006098522.1","XP_006109297.1",0.824],["XP_006098522.1","XP_006107148.1",0.911],["XP_006098522.1","XP_006106480.1",0.938],["XP_006098522.1","XP_006103735.1",0.845],["XP_006098522.1","XP_006102269.1",0.901],["XP_006098522.1","XP_014319582.1",0.915],["XP_006098522.1","XP_014316749.1",0.943],["XP_006098522.1","XP_014306040.1",0.844],["XP_006083727.1","XP_006082432.2",0.989],["XP_006083727.1","XP_006089365.1",0.993],["XP_006083727.1","XP_006090849.1",0.984],["XP_006083727.1","XP_006088139.1",0.947],["XP_006083727.1","XP_006086831.1",0.972],["XP_006083727.1","XP_006085573.1",0.928],["XP_006083727.1","XP_006109297.1",0.985],["XP_006083727.1","XP_006107148.1",0.937],["XP_006083727.1","XP_006106480.1",0.957],["XP_006083727.1","XP_006103735.1",0.894],["XP_006083727.1","XP_006102269.1",0.956],["XP_006083727.1","XP_006097325.1",0.976],["XP_006083727.1","XP_014319582.1",0.946],["XP_006083727.1","XP_014316749.1",0.911],["XP_006083727.1","XP_014306040.1",0.991],["XP_014316749.1","XP_006106480.1",0.899],["XP_014316749.1","XP_006107148.1",0.864],["XP_014316749.1","XP_006109297.1",0.969],["XP_014316749.1","XP_014306040.1",0.895],["XP_014316749.1","XP_014319582.1",0.965],["XP_014316749.1","XP_006082432.2",0.976],["XP_014316749.1","XP_006085573.1",0.952],["XP_014316749.1","XP_006086831.1",0.856],["XP_014316749.1","XP_006088139.1",0.978],["XP_014316749.1","XP_006089365.1",0.975],["XP_014316749.1","XP_006090849.1",0.9],["XP_014316749.1","XP_006097325.1",0.967],["XP_014316749.1","XP_006102269.1",0.926],["XP_014316749.1","XP_006103735.1",0.797],["XP_006109297.1","XP_014306040.1",0.985],["XP_006109297.1","XP_014319582.1",0.967],["XP_006109297.1","XP_006082432.2",0.979],["XP_006109297.1","XP_006085573.1",0.959],["XP_006109297.1","XP_006086831.1",0.849],["XP_006109297.1","XP_006088139.1",0.902],["XP_006109297.1","XP_006089365.1",0.984],["XP_006109297.1","XP_006090849.1",0.981],["XP_006109297.1","XP_006097325.1",0.954],["XP_006109297.1","XP_006102269.1",0.884],["XP_006109297.1","XP_006103735.1",0.909],["XP_006109297.1","XP_006106480.1",0.961],["XP_006109297.1","XP_006107148.1",0.977],["XP_006088139.1","XP_006082432.2",0.979],["XP_006088139.1","XP_006085573.1",0.952],["XP_006088139.1","XP_006086831.1",0.972],["XP_006088139.1","XP_006089365.1",0.96],["XP_006088139.1","XP_006090849.1",0.923],["XP_006088139.1","XP_006097325.1",0.97],["XP_006088139.1","XP_006102269.1",0.967],["XP_006088139.1","XP_006103735.1",0.97],["XP_006088139.1","XP_006106480.1",0.981],["XP_006088139.1","XP_006107148.1",0.974],["XP_006088139.1","XP_014306040.1",0.943],["XP_006088139.1","XP_014319582.1",0.901],["XP_006086831.1","XP_006082432.2",0.986],["XP_006086831.1","XP_006085573.1",0.982],["XP_006086831.1","XP_006089365.1",0.979],["XP_006086831.1","XP_006090849.1",0.971],["XP_006086831.1","XP_006107148.1",0.928],["XP_006086831.1","XP_006106480.1",0.981],["XP_006086831.1","XP_006103735.1",0.898],["XP_006086831.1","XP_006102269.1",0.982],["XP_006086831.1","XP_006097325.1",0.918],["XP_006086831.1","XP_014319582.1",0.967],["XP_006086831.1","XP_014306040.1",0.976],["XP_014319582.1","XP_006106480.1",0.977],["XP_014319582.1","XP_006107148.1",0.97],["XP_014319582.1","XP_014306040.1",0.938],["XP_014319582.1","XP_006082432.2",0.784],["XP_014319582.1","XP_006085573.1",0.945],["XP_014319582.1","XP_006089365.1",0.975],["XP_014319582.1","XP_006090849.1",0.954],["XP_014319582.1","XP_006097325.1",0.812],["XP_014319582.1","XP_006102269.1",0.954],["XP_014319582.1","XP_006103735.1",0.923],["XP_006107148.1","XP_014306040.1",0.968],["XP_006107148.1","XP_006082432.2",0.979],["XP_006107148.1","XP_006085573.1",0.973],["XP_006107148.1","XP_006089365.1",0.984],["XP_006107148.1","XP_006090849.1",0.987],["XP_006107148.1","XP_006097325.1",0.981],["XP_006107148.1","XP_006102269.1",0.952],["XP_006107148.1","XP_006103735.1",0.899],["XP_006107148.1","XP_006106480.1",0.976],["XP_006082432.2","XP_006085573.1",0.977],["XP_006082432.2","XP_006089365.1",0.989],["XP_006082432.2","XP_006090849.1",0.99],["XP_006082432.2","XP_006097325.1",0.892],["XP_006082432.2","XP_006102269.1",0.984],["XP_006082432.2","XP_006103735.1",0.919],["XP_006082432.2","XP_006106480.1",0.978],["XP_006082432.2","XP_014306040.1",0.989],["XP_006103735.1","XP_006085573.1",0.888],["XP_006103735.1","XP_006089365.1",0.92],["XP_006103735.1","XP_006090849.1",0.913],["XP_006103735.1","XP_006097325.1",0.701],["XP_006103735.1","XP_006102269.1",0.93],["XP_006103735.1","XP_006106480.1",0.962],["XP_006103735.1","XP_014306040.1",0.883],["XP_006089365.1","XP_006085573.1",0.954],["XP_006089365.1","XP_006090849.1",0.944],["XP_006089365.1","XP_006097325.1",0.96],["XP_006089365.1","XP_006102269.1",0.955],["XP_006089365.1","XP_006106480.1",0.982],["XP_006089365.1","XP_014306040.1",0.993],["XP_006102269.1","XP_006085573.1",0.984],["XP_006102269.1","XP_006090849.1",0.968],["XP_006102269.1","XP_006097325.1",0.971],["XP_006102269.1","XP_006106480.1",0.914],["XP_006102269.1","XP_014306040.1",0.954],["XP_006090849.1","XP_006085573.1",0.937],["XP_006090849.1","XP_006097325.1",0.971],["XP_006090849.1","XP_006106480.1",0.969],["XP_006090849.1","XP_014306040.1",0.983],["XP_006106480.1","XP_014306040.1",0.95],["XP_006106480.1","XP_006085573.1",0.958],["XP_006106480.1","XP_006097325.1",0.957],["XP_006085573.1","XP_006097325.1",0.942],["XP_006085573.1","XP_014306040.1",0.924],["XP_006097325.1","XP_014306040.1",0.976]],"all_go_terms":{"GO:2001171":1,"GO:0034214":1,"GO:1990171":1,"GO:0006272":1,"GO:1903007":1,"GO:0019079":1,"GO:0070389":1,"GO:0035494":1,"GO:0070407":1,"GO:0016485":1,"GO:0016562":1,"GO:0051013":1,"GO:0034599":1,"GO:0010304":1,"GO:0061738":1,"GO:0071218":1,"GO:0070676":1,"GO:0006260":1,"GO:0030420":1,"GO:0006406":1,"GO:1903724":1,"GO:0010206":1,"GO:0061166":1,"GO:0070651":1,"GO:0000733":1,"GO:0032979":1,"GO:0030968":1,"GO:0030150":2,"GO:0045053":1,"GO:0071712":1,"GO:0032968":1,"GO:0018279":1,"GO:0006888":1,"GO:0035617":1,"GO:1901800":1,"GO:0070842":1,"GO:0072389":1,"GO:0030433":1,"GO:0006515":1,"GO:0051131":1,"GO:0034551":1,"GO:0070414":1,"GO:0090296":1,"GO:0031117":1,"GO:0030163":1,"GO:0051260":1,"GO:0097352":1,"GO:0033314":1,"GO:0070682":1,"GO:0001319":1,"GO:0045041":1,"GO:0090261":1,"GO:2000158":1,"GO:0016558":1,"GO:0045899":1,"GO:1903862":1,"GO:0070914":1,"GO:0070370":1,"GO:0001824":1,"GO:0070987":1,"GO:1903715":1,"GO:0051301":1,"GO:0061641":1,"GO:0010205":1,"GO:0060013":1,"GO:0043335":1,"GO:0046034":1,"GO:0048219":1,"GO:0031426":1,"GO:0010239":1,"GO:0080163":1,"GO:0043086":1,"GO:0048507":1,"GO:0006744":1,"GO:0006412":4,"GO:1901030":1,"GO:0006783":1,"GO:0032780":1,"GO:0030218":1,"GO:1903578":1,"GO:0001937":1,"GO:0051882":1,"GO:1904925":1,"GO:1903214":1,"GO:0036444":2,"GO:0051561":2,"GO:0033617":3,"GO:0010082":1,"GO:0070131":1,"GO:0010636":1,"GO:0016540":1,"GO:0010954":1,"GO:0006656":1,"GO:0006646":1,"GO:0071500":2,"GO:0043154":2,"GO:0072592":2,"GO:0009812":2,"GO:0070814":2,"GO:1902177":2,"GO:0072606":2,"GO:0071375":2,"GO:0048855":2,"GO:0010467":2,"GO:0042493":2,"GO:0043602":2,"GO:0031284":2,"GO:0071372":2,"GO:0006809":2,"GO:0032332":2,"GO:0009590":2,"GO:0046210":2,"GO:0003081":2,"GO:0000103":2,"GO:0045880":2,"GO:1901300":2,"GO:0006814":2,"GO:0019344":2,"GO:0032310":2,"GO:0045730":2,"GO:0044205":2,"GO:0009437":2,"GO:0042554":2,"GO:0009636":2,"GO:0010124":2,"GO:0018393":2,"GO:0032770":2,"GO:0014806":2,"GO:0003420":2,"GO:0019395":2,"GO:0098924":2,"GO:0090031":2,"GO:0006695":2,"GO:0048840":2,"GO:0045453":2,"GO:0045429":2,"GO:0072604":2,"GO:0018119":2,"GO:0006590":2,"GO:0090346":2,"GO:0045542":2,"GO:1904042":2,"GO:1990451":2,"GO:0014740":2,"GO:0051591":2,"GO:0060192":2,"GO:0006696":2,"GO:0015677":2,"GO:0045726":2,"GO:0050665":2,"GO:0007584":2,"GO:0070988":2,"GO:0008365":2,"GO:1904845":2,"GO:1901206":2,"GO:0042128":2,"GO:0032981":1,"GO:0090351":1,"GO:0050881":1,"GO:0070584":1,"GO:0050905":1,"GO:0019216":1,"GO:0031413":1,"GO:0070124":1},"recipe_readded":[]}