{"hash":"2088732785228502120","title":"Gene expression and cell proliferation","description":"The cluster centers on core processes that drive cell growth and division: transcription (DNA-templated transcription), translation readiness (tRNA aminoacylation), and protein assembly (protein homotetramerization), plus nucleotide biosynthesis (GTP/GMP) and metabolic responses (glucose starvation). The presence of mitotic regulation and lymphocyte proliferation further ties to cell-cycle\u2013driven proliferation. Together, these terms suggest a cohesive theme around gene expression machinery supporting cell growth and division.","confidence":"Medium","size":21,"edges":54,"triangles":54,"max_degree":11,"top_function":"DNA-templated transcription","members":[{"accession":"NP_014213.2","go_terms":["GO:0000289","GO:0010606","GO:0006397","GO:0034729","GO:0000245","GO:0048149","GO:1990108","GO:0071108","GO:0021551","GO:0051568","GO:0001662","GO:0035871","GO:0008583","GO:1904667","GO:0010995","GO:0070537","GO:0010992","GO:1904378","GO:0060013","GO:1903070","GO:0035520","GO:0035523","GO:0008343","GO:0044313","GO:1900425","GO:1901026","GO:0035192","GO:0006355","GO:0006511","GO:0006351","GO:0035616"]},{"accession":"NP_001106172.4","go_terms":[]},{"accession":"NP_010152.1","go_terms":["GO:0030218","GO:0051882","GO:0032780","GO:1904925","GO:1903578","GO:1903214","GO:1901030","GO:0006783","GO:0001937"]},{"accession":"NP_011968.1","go_terms":["GO:0032049","GO:0046838","GO:0030836","GO:0016311","GO:0032361","GO:0009244","GO:0071318","GO:0097171","GO:0031247","GO:0009103"]},{"accession":"NP_014089.2","go_terms":["GO:0050821","GO:0030150"]},{"accession":"NP_014152.1","go_terms":["GO:0006423","GO:0010125","GO:0006431","GO:0006429"]},{"accession":"NP_014299.1","go_terms":["GO:0042407"]},{"accession":"NP_001257688.1","go_terms":[]},{"accession":"NP_012763.1","go_terms":["GO:0035039","GO:0034608","GO:0046008","GO:0034606","GO:0070884","GO:0033173"]},{"accession":"NP_011506.1","go_terms":["GO:0019878","GO:0006879","GO:0019679","GO:0006099","GO:0050892","GO:0009791","GO:1990641","GO:0009098","GO:0009097","GO:0010040","GO:0032543","GO:0019298"]},{"accession":"NP_012088.3","go_terms":["GO:0051289","GO:0055114","GO:0071353","GO:0060041","GO:0046651","GO:0006177","GO:0006144","GO:0006183","GO:0006633","GO:0042149","GO:0032147","GO:0030071","GO:0006565","GO:0006535","GO:0031460","GO:0045722","GO:1902593","GO:1903830","GO:0043418","GO:0005975","GO:0070814","GO:0019346","GO:0019343"]},{"accession":"NP_013536.3","go_terms":["GO:0001561","GO:0018924","GO:0019516","GO:0046296","GO:0009853","GO:0008299","GO:0009854","GO:0051289","GO:0055114","GO:0071353","GO:0060041","GO:0046651","GO:0006177","GO:0006144","GO:0006183","GO:0006633","GO:0042149","GO:0032147","GO:0030071","GO:0006565","GO:0006535","GO:0031460","GO:0045722","GO:1902593","GO:1903830","GO:0043418","GO:0005975","GO:0070814","GO:0019346","GO:0019343"]},{"accession":"NP_013656.1","go_terms":["GO:0001561","GO:0018924","GO:0019516","GO:0046296","GO:0009853","GO:0008299","GO:0009854","GO:0051289","GO:0055114","GO:0071353","GO:0060041","GO:0046651","GO:0006177","GO:0006144","GO:0006183","GO:0006633","GO:0042149","GO:0032147","GO:0030071","GO:0006565","GO:0006535","GO:0031460","GO:0045722","GO:1902593","GO:1903830","GO:0043418","GO:0005975","GO:0070814","GO:0019346","GO:0019343"]},{"accession":"NP_010729.3","go_terms":["GO:0044205","GO:0007595","GO:0032869","GO:0046651","GO:0046110","GO:0045982","GO:0019835","GO:0006223","GO:0006541","GO:0006178","GO:0006015","GO:0043103","GO:0007626","GO:0007625","GO:0046038","GO:0021756","GO:0006353","GO:0042417","GO:0045892","GO:0021954","GO:0021895","GO:0044209","GO:0032263","GO:0032265","GO:0032264","GO:0001975","GO:0048813","GO:0006351","GO:0006207","GO:0006189","GO:0006168"]},{"accession":"NP_011780.3","go_terms":["GO:0006431","GO:0006450","GO:0006438","GO:0006428","GO:0006429","GO:0006412"]},{"accession":"NP_013690.1","go_terms":["GO:0044205","GO:0007595","GO:0032869","GO:0046651","GO:0046110","GO:0045982","GO:0019835","GO:0006223","GO:0006541","GO:0006178","GO:0006015","GO:0043103","GO:0007626","GO:0007625","GO:0046038","GO:0021756","GO:0006353","GO:0042417","GO:0045892","GO:0021954","GO:0021895","GO:0044209","GO:0032263","GO:0032265","GO:0032264","GO:0001975","GO:0048813","GO:0006351","GO:0006207","GO:0006189","GO:0006168"]},{"accession":"NP_014980.3","go_terms":["GO:0006310","GO:0090305","GO:0006450","GO:0006281","GO:0070143","GO:0006435"]},{"accession":"NP_015165.1","go_terms":["GO:0006423","GO:0010125","GO:0006450","GO:0006431","GO:0006438","GO:0006428","GO:0006429","GO:0006412"]},{"accession":"NP_001335768.1","go_terms":[]},{"accession":"NP_014487.1","go_terms":[]},{"accession":"NP_014543.1","go_terms":["GO:0046718","GO:0051289","GO:1902600","GO:0044257","GO:0009060","GO:0071432","GO:1901143","GO:0032461","GO:0010992","GO:0008286","GO:0051291","GO:0006627","GO:0010815","GO:0042447","GO:0008340","GO:0018189","GO:0006122","GO:0016032","GO:0045861"]}],"graph":[["NP_014213.2","NP_001106172.4",0.748],["NP_014213.2","NP_001257688.1",0.715],["NP_014213.2","NP_010152.1",0.709],["NP_014213.2","NP_011506.1",0.625],["NP_014213.2","NP_011780.3",0.505],["NP_014213.2","NP_013690.1",0.739],["NP_014213.2","NP_014152.1",0.573],["NP_012088.3","NP_010729.3",0.577],["NP_012088.3","NP_011506.1",0.752],["NP_012088.3","NP_013536.3",0.767],["NP_012088.3","NP_013656.1",0.784],["NP_012088.3","NP_013690.1",0.596],["NP_014089.2","NP_001106172.4",0.618],["NP_014089.2","NP_010152.1",0.598],["NP_014089.2","NP_011968.1",0.811],["NP_014089.2","NP_014152.1",0.732],["NP_014089.2","NP_014543.1",0.791],["NP_011968.1","NP_001106172.4",0.888],["NP_011968.1","NP_010152.1",0.758],["NP_011968.1","NP_013690.1",0.566],["NP_011968.1","NP_014299.1",0.567],["NP_011968.1","NP_014543.1",0.534],["NP_014299.1","NP_001335768.1",0.8],["NP_014299.1","NP_010152.1",0.655],["NP_010729.3","NP_011780.3",0.699],["NP_010729.3","NP_013536.3",0.635],["NP_010729.3","NP_013656.1",0.594],["NP_010729.3","NP_013690.1",0.725],["NP_010729.3","NP_014152.1",0.639],["NP_010729.3","NP_014980.3",0.543],["NP_010729.3","NP_015165.1",0.607],["NP_001106172.4","NP_010152.1",0.758],["NP_001106172.4","NP_014543.1",0.532],["NP_001335768.1","NP_001257688.1",0.751],["NP_011506.1","NP_014543.1",0.536],["NP_011506.1","NP_013536.3",0.74],["NP_011506.1","NP_013656.1",0.746],["NP_011506.1","NP_013690.1",0.556],["NP_013536.3","NP_013656.1",0.755],["NP_013536.3","NP_013690.1",0.623],["NP_014543.1","NP_010152.1",0.61],["NP_014543.1","NP_015165.1",0.51],["NP_011780.3","NP_014980.3",0.629],["NP_011780.3","NP_015165.1",0.743],["NP_011780.3","NP_014152.1",0.776],["NP_011780.3","NP_013690.1",0.669],["NP_010152.1","NP_014152.1",0.681],["NP_015165.1","NP_013690.1",0.624],["NP_015165.1","NP_014152.1",0.766],["NP_015165.1","NP_014980.3",0.779],["NP_013690.1","NP_013656.1",0.612],["NP_013690.1","NP_014152.1",0.637],["NP_013690.1","NP_014980.3",0.577],["NP_014980.3","NP_014152.1",0.745]],"all_go_terms":{"GO:0048149":1,"GO:0035523":1,"GO:1904667":1,"GO:0000289":1,"GO:0044313":1,"GO:1900425":1,"GO:1904378":1,"GO:0006355":1,"GO:0008343":1,"GO:1903070":1,"GO:1990108":1,"GO:0035192":1,"GO:0010995":1,"GO:0070537":1,"GO:0006397":1,"GO:0010606":1,"GO:0071108":1,"GO:1901026":1,"GO:0006351":3,"GO:0035871":1,"GO:0000245":1,"GO:0034729":1,"GO:0021551":1,"GO:0010992":2,"GO:0008583":1,"GO:0051568":1,"GO:0006511":1,"GO:0035520":1,"GO:0060013":1,"GO:0035616":1,"GO:0001662":1,"GO:0032780":1,"GO:1903214":1,"GO:0006783":1,"GO:1903578":1,"GO:0001937":1,"GO:0030218":1,"GO:0051882":1,"GO:1901030":1,"GO:1904925":1,"GO:0016311":1,"GO:0032049":1,"GO:0031247":1,"GO:0030836":1,"GO:0009244":1,"GO:0009103":1,"GO:0097171":1,"GO:0046838":1,"GO:0032361":1,"GO:0071318":1,"GO:0050821":1,"GO:0030150":1,"GO:0006431":3,"GO:0006429":3,"GO:0010125":2,"GO:0006423":2,"GO:0042407":1,"GO:0035039":1,"GO:0034608":1,"GO:0046008":1,"GO:0033173":1,"GO:0070884":1,"GO:0034606":1,"GO:0009791":1,"GO:0010040":1,"GO:0050892":1,"GO:0032543":1,"GO:0019679":1,"GO:0006099":1,"GO:1990641":1,"GO:0019298":1,"GO:0009097":1,"GO:0006879":1,"GO:0009098":1,"GO:0019878":1,"GO:0006183":3,"GO:0006177":3,"GO:0030071":3,"GO:0042149":3,"GO:0055114":3,"GO:0060041":3,"GO:0071353":3,"GO:0051289":4,"GO:0043418":3,"GO:0006535":3,"GO:0070814":3,"GO:0006565":3,"GO:0019346":3,"GO:0006633":3,"GO:0032147":3,"GO:0019343":3,"GO:0005975":3,"GO:0046651":5,"GO:1903830":3,"GO:0045722":3,"GO:1902593":3,"GO:0031460":3,"GO:0006144":3,"GO:0018924":2,"GO:0009854":2,"GO:0046296":2,"GO:0019516":2,"GO:0001561":2,"GO:0008299":2,"GO:0009853":2,"GO:0001975":2,"GO:0007626":2,"GO:0006015":2,"GO:0046110":2,"GO:0044205":2,"GO:0048813":2,"GO:0032265":2,"GO:0006189":2,"GO:0045982":2,"GO:0044209":2,"GO:0043103":2,"GO:0006223":2,"GO:0006353":2,"GO:0006207":2,"GO:0006168":2,"GO:0007625":2,"GO:0006541":2,"GO:0032264":2,"GO:0021895":2,"GO:0021954":2,"GO:0042417":2,"GO:0032263":2,"GO:0007595":2,"GO:0021756":2,"GO:0046038":2,"GO:0006178":2,"GO:0032869":2,"GO:0019835":2,"GO:0045892":2,"GO:0006450":3,"GO:0006428":2,"GO:0006438":2,"GO:0006412":2,"GO:0006310":1,"GO:0006281":1,"GO:0090305":1,"GO:0006435":1,"GO:0070143":1,"GO:0046718":1,"GO:0032461":1,"GO:0045861":1,"GO:0044257":1,"GO:0018189":1,"GO:0016032":1,"GO:1901143":1,"GO:0051291":1,"GO:0071432":1,"GO:0010815":1,"GO:0042447":1,"GO:0008340":1,"GO:0006122":1,"GO:0008286":1,"GO:0009060":1,"GO:0006627":1,"GO:1902600":1},"recipe_readded":[]}