{"hash":"2023771856206134805","title":"Mitochondrial lipid metabolism and energy production","description":"This cluster is driven by lipid biosynthesis and remodeling processes (platelet activating factor biosynthesis, cardiolipin remodeling, ether lipid biosynthesis, phosphatidylcholine biosynthesis, CDP-diacylglycerol biosynthesis) and by mitochondrial ATP synthesis, pointing to a cohesive theme of mitochondrial lipid metabolism coupled to energy production. Immune-related terms (IL-2 production, regulation of T cell activation-induced cell death) may reflect roles of mitochondria in immune cell signaling but are less central to the main theme. Developmental terms like cerebellum morphogenesis and glandular epithelial maturation appear peripheral to the core lipid/mitochondrial signal. Overall, the cluster aligns best with mitochondrial lipid metabolism and energy generation.","confidence":"Medium","size":8,"edges":4,"triangles":1,"max_degree":2,"top_function":null,"members":[{"accession":"NP_001257675.1","go_terms":[]},{"accession":"NP_015466.1","go_terms":["GO:0070970","GO:0042775","GO:0036151","GO:0010143","GO:2001246","GO:0021587","GO:0070236","GO:0035965","GO:0016024","GO:0019432","GO:0002071","GO:0006663","GO:0008611"]},{"accession":"NP_010301.1","go_terms":["GO:0070970","GO:0042775","GO:0036151","GO:0010143","GO:2001246","GO:0021587","GO:0070236","GO:0035965","GO:0016024","GO:0019432","GO:0002071","GO:0006663","GO:0008611","GO:0060217","GO:0036149"]},{"accession":"NP_013147.1","go_terms":["GO:0006950","GO:1905329"]},{"accession":"NP_014965.3","go_terms":[]},{"accession":"NP_009598.1","go_terms":["GO:0070970","GO:0042775","GO:0036151","GO:0010143","GO:2001246","GO:0021587","GO:0070236","GO:0035965","GO:0016024","GO:0019432","GO:0002071","GO:0006663","GO:0008611","GO:0060217","GO:0036149"]},{"accession":"NP_009594.1","go_terms":["GO:0075015","GO:0006031","GO:0001744","GO:0007299","GO:0042248","GO:0000916","GO:0000918","GO:0000920","GO:0071555","GO:0034217"]},{"accession":"NP_010357.3","go_terms":["GO:0030148","GO:0006676","GO:0006655","GO:0009395","GO:0015760","GO:1902068","GO:0035233","GO:0006668","GO:0044329","GO:0044328","GO:0044330","GO:0046839","GO:0098869","GO:0006670"]}],"graph":[["NP_014965.3","NP_009594.1",0.801],["NP_015466.1","NP_009598.1",0.64],["NP_015466.1","NP_010301.1",0.639],["NP_010301.1","NP_009598.1",0.654]],"all_go_terms":{"GO:0006663":3,"GO:0021587":3,"GO:0070236":3,"GO:2001246":3,"GO:0035965":3,"GO:0042775":3,"GO:0070970":3,"GO:0016024":3,"GO:0002071":3,"GO:0008611":3,"GO:0036151":3,"GO:0019432":3,"GO:0010143":3,"GO:0060217":2,"GO:0036149":2,"GO:1905329":1,"GO:0006950":1,"GO:0006031":1,"GO:0007299":1,"GO:0000916":1,"GO:0042248":1,"GO:0071555":1,"GO:0075015":1,"GO:0000920":1,"GO:0034217":1,"GO:0000918":1,"GO:0001744":1,"GO:0035233":1,"GO:0009395":1,"GO:1902068":1,"GO:0044330":1,"GO:0015760":1,"GO:0006655":1,"GO:0098869":1,"GO:0044328":1,"GO:0030148":1,"GO:0044329":1,"GO:0006668":1,"GO:0046839":1,"GO:0006670":1,"GO:0006676":1},"recipe_readded":["NP_011462.1","NP_015509.1","NP_014240.1","NP_012955.1","NP_013867.2","NP_011962.1","NP_011688.3","NP_010873.1","NP_012534.1","NP_010369.3","NP_014319.1","NP_014746.2","NP_012583.1","NP_011540.3","NP_010962.1","NP_015150.2","NP_014386.2","NP_010316.1","NP_014489.2","NP_012979.3"]}