{"hash":"1414588057613797815","title":"Ribosome biogenesis and protein quality control","description":"The cluster is dominated by ribosome-related processes: ribosome biogenesis, ribosomal small subunit assembly, and translation, indicating a focus on ribosome production and function. Supporting this, chaperone-mediated protein complex assembly and proteasome regulatory particle assembly point to a coordinated protein folding and degradation system ensuring ribosome assembly quality, with autophagy-related turnover also fitting into this protein homeostasis network. Some terms (transcription elongation regulation and proton transport) are more peripheral but do not negate the core ribosome/protein quality theme.","confidence":"Medium","size":9,"edges":15,"triangles":7,"max_degree":5,"top_function":null,"members":[{"accession":"NP_014435.3","go_terms":["GO:0042254","GO:0000028","GO:0006412","GO:0006407"]},{"accession":"NP_010216.1","go_terms":[]},{"accession":"NP_010663.1","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0032981","GO:0033617"]},{"accession":"NP_011905.1","go_terms":["GO:1902600","GO:0007035"]},{"accession":"NP_013499.1","go_terms":["GO:1902600","GO:0006123"]},{"accession":"NP_015222.1","go_terms":["GO:0009395","GO:0090503","GO:0046381","GO:0070291","GO:0008033","GO:0070292","GO:0018189","GO:0072684","GO:0035900","GO:0006364","GO:0006198","GO:0006401","GO:1903999","GO:0019700"]},{"accession":"NP_010257.1","go_terms":[]},{"accession":"NP_012356.2","go_terms":["GO:0007021","GO:0051131","GO:0006457","GO:0071629","GO:0032968","GO:0043622"]},{"accession":"NP_012975.3","go_terms":[]}],"graph":[["NP_012975.3","NP_010216.1",0.503],["NP_012975.3","NP_014435.3",0.569],["NP_012975.3","NP_013499.1",0.626],["NP_012356.2","NP_010216.1",0.723],["NP_012356.2","NP_010663.1",0.574],["NP_012356.2","NP_011905.1",0.64],["NP_014435.3","NP_010257.1",0.51],["NP_014435.3","NP_013499.1",0.568],["NP_013499.1","NP_010216.1",0.546],["NP_013499.1","NP_010257.1",0.677],["NP_013499.1","NP_015222.1",0.713],["NP_010257.1","NP_015222.1",0.535],["NP_010216.1","NP_015222.1",0.541],["NP_010216.1","NP_011905.1",0.652],["NP_010663.1","NP_011905.1",0.672]],"all_go_terms":{"GO:0006412":1,"GO:0006407":1,"GO:0000028":1,"GO:0042254":1,"GO:0016485":1,"GO:0061738":1,"GO:0070682":1,"GO:0001319":1,"GO:0032981":1,"GO:0019079":1,"GO:0070370":1,"GO:0016562":1,"GO:0030420":1,"GO:0051131":2,"GO:0033617":1,"GO:0048219":1,"GO:0001824":1,"GO:0034214":1,"GO:0030968":1,"GO:0035494":1,"GO:0030433":1,"GO:0034599":1,"GO:0070842":1,"GO:0090261":1,"GO:0043335":1,"GO:2001171":1,"GO:0031117":1,"GO:0072389":1,"GO:0051301":1,"GO:0051260":1,"GO:0070914":1,"GO:0070676":1,"GO:0070651":1,"GO:0032979":1,"GO:0070407":1,"GO:0033314":1,"GO:2000158":1,"GO:0006406":1,"GO:0035617":1,"GO:1901800":1,"GO:0090296":1,"GO:1903715":1,"GO:0000733":1,"GO:0006260":1,"GO:0016558":1,"GO:0071218":1,"GO:0045053":1,"GO:0006272":1,"GO:0034551":1,"GO:0070414":1,"GO:1903862":1,"GO:0070389":1,"GO:1903724":1,"GO:0045041":1,"GO:0061641":1,"GO:0097352":1,"GO:0051013":1,"GO:0018279":1,"GO:0071712":1,"GO:0070987":1,"GO:1990171":1,"GO:0046034":1,"GO:0061166":1,"GO:0006888":1,"GO:1903007":1,"GO:0032968":2,"GO:0045899":1,"GO:0007035":1,"GO:1902600":2,"GO:0006123":1,"GO:0009395":1,"GO:0019700":1,"GO:0072684":1,"GO:0006198":1,"GO:1903999":1,"GO:0018189":1,"GO:0070292":1,"GO:0046381":1,"GO:0006364":1,"GO:0090503":1,"GO:0070291":1,"GO:0006401":1,"GO:0008033":1,"GO:0035900":1,"GO:0043622":1,"GO:0071629":1,"GO:0006457":1,"GO:0007021":1},"recipe_readded":[]}