{"hash":"1291089132958641775","title":"Endocytic trafficking and lysosome targeting","description":"The GO terms cluster around vesicle transport between the plasma membrane, endosomes, and lysosomes, including ER-to-Golgi transport and endocytic recycling, plus a signaling link via neurotrophin receptor pathways; these collectively indicate a coherent group of proteins involved in intracellular vesicle trafficking and lysosome-related processes, with some involvement in membrane remodeling during differentiation. ","confidence":"High","size":8,"edges":5,"triangles":1,"max_degree":3,"top_function":null,"members":[{"accession":"NP_011695.1","go_terms":[]},{"accession":"NP_001418069.1","go_terms":[]},{"accession":"NP_010025.1","go_terms":["GO:0048227","GO:0046323","GO:2001137","GO:1900452","GO:1902997","GO:0070863","GO:0008625","GO:1902771","GO:1902955","GO:0032460","GO:1902953","GO:0014902","GO:0006622","GO:1902430","GO:0048011","GO:0006895","GO:0051005","GO:1902960","GO:1902963","GO:1902948","GO:1902966"]},{"accession":"NP_015137.1","go_terms":["GO:0000750","GO:0007618"]},{"accession":"NP_012377.1","go_terms":["GO:0071497","GO:0031505"]},{"accession":"NP_014464.3","go_terms":["GO:0048227","GO:0046323","GO:2001137","GO:1900452","GO:1902997","GO:0070863","GO:0008625","GO:1902771","GO:1902955","GO:0032460","GO:1902953","GO:0014902","GO:0006622","GO:1902430","GO:0048011","GO:0006895","GO:0051005","GO:1902960","GO:1902963","GO:1902948","GO:1902966","GO:0005975"]},{"accession":"NP_013721.1","go_terms":["GO:0006654","GO:0071236","GO:0036151","GO:0036150","GO:0036152","GO:0070583","GO:0050482","GO:0036148","GO:0036149","GO:0035965","GO:0001516","GO:0006660","GO:0006663"]},{"accession":"NP_014632.1","go_terms":["GO:0006654","GO:0071236","GO:0036151","GO:0036150","GO:0036152","GO:0070583","GO:0050482","GO:0036148","GO:0036149","GO:0035965","GO:0001516","GO:0006660","GO:0006663"]}],"graph":[["NP_014632.1","NP_010025.1",0.637],["NP_014632.1","NP_013721.1",0.56],["NP_014464.3","NP_010025.1",0.538],["NP_010025.1","NP_013721.1",0.662],["NP_013721.1","NP_015137.1",0.733]],"all_go_terms":{"GO:0048227":2,"GO:1902953":2,"GO:0051005":2,"GO:0014902":2,"GO:0048011":2,"GO:0006622":2,"GO:1902771":2,"GO:0032460":2,"GO:2001137":2,"GO:1902955":2,"GO:1900452":2,"GO:1902966":2,"GO:0006895":2,"GO:1902430":2,"GO:0046323":2,"GO:0008625":2,"GO:1902948":2,"GO:1902960":2,"GO:1902963":2,"GO:1902997":2,"GO:0070863":2,"GO:0000750":1,"GO:0007618":1,"GO:0071497":1,"GO:0031505":1,"GO:0005975":1,"GO:0006663":2,"GO:0036152":2,"GO:0006660":2,"GO:0035965":2,"GO:0036148":2,"GO:0036149":2,"GO:0071236":2,"GO:0070583":2,"GO:0006654":2,"GO:0050482":2,"GO:0036151":2,"GO:0036150":2,"GO:0001516":2},"recipe_readded":["NP_009311.2","NP_012701.2","NP_009327.1","NP_011286.1","NP_010703.1","NP_013732.1","NP_013578.1","NP_014386.2","NP_012147.3","NP_010036.1","NP_010845.1","NP_012665.3","NP_010849.3","NP_010744.3","NP_012072.3","NP_011312.1","NP_012136.1","NP_014081.1","NP_013624.1","NP_012111.1"]}