{"hash":"647437428669344262","title":"Ubiquitin-mediated innate immune signaling and apoptosis","description":"The GO terms converge on ubiquitination processes (protein ubiquitination, autoubiquitination, K6-linked ubiquitination) alongside immune signaling regulation (adaptive immune response, negative regulation of RIG-I signaling, NF-kappaB activation) and apoptosis control, with some antiviral transport regulation. This suggests a functional module where ubiquitin networks modulate innate immune responses and cell fate decisions, rather than a single physical complex, making a coherent, albeit sparse, immune-apoptosis regulatory cluster.","confidence":"Medium","size":3,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_013752946.1","go_terms":["GO:0016567","GO:0039536","GO:0002250","GO:0033151","GO:0033209","GO:0009048","GO:0036205","GO:0046328","GO:2000620","GO:0042981","GO:0007250","GO:0070512","GO:0085020","GO:0042787","GO:0070535","GO:1903265","GO:1903762","GO:1903721","GO:1901253","GO:0090073","GO:0051865"]},{"accession":"XP_013754630.1","go_terms":["GO:0032436","GO:0001701","GO:0048142","GO:0043248","GO:0007127","GO:0075525","GO:0000122","GO:0008283","GO:0002188","GO:0035914","GO:1902416","GO:0071033","GO:0006283","GO:0030182","GO:0070196","GO:0000338","GO:0075522","GO:0006446","GO:0034260","GO:0070321","GO:0010972","GO:0048863","GO:0001732","GO:0001731","GO:0048140","GO:0036099","GO:0090054","GO:0090052","GO:0000715","GO:0000973","GO:0006511"]},{"accession":"XP_013753106.1","go_terms":["GO:0007097"]}],"graph":[],"all_go_terms":{"GO:0036205":1,"GO:0002250":1,"GO:0039536":1,"GO:0016567":1,"GO:0042981":1,"GO:0085020":1,"GO:0007250":1,"GO:0070512":1,"GO:0051865":1,"GO:1901253":1,"GO:1903721":1,"GO:1903762":1,"GO:2000620":1,"GO:0046328":1,"GO:0090073":1,"GO:0033151":1,"GO:0042787":1,"GO:0009048":1,"GO:0033209":1,"GO:0070535":1,"GO:1903265":1,"GO:0030182":1,"GO:0070196":1,"GO:0006283":1,"GO:0001732":1,"GO:0001731":1,"GO:0071033":1,"GO:0006511":1,"GO:0008283":1,"GO:0048140":1,"GO:0000338":1,"GO:0048142":1,"GO:0006446":1,"GO:1902416":1,"GO:0034260":1,"GO:0000122":1,"GO:0000715":1,"GO:0032436":1,"GO:0070321":1,"GO:0075522":1,"GO:0048863":1,"GO:0090052":1,"GO:0035914":1,"GO:0002188":1,"GO:0075525":1,"GO:0043248":1,"GO:0090054":1,"GO:0001701":1,"GO:0000973":1,"GO:0010972":1,"GO:0007127":1,"GO:0036099":1,"GO:0007097":1},"recipe_readded":["XP_013759624.1","XP_013758423.1","XP_013760324.1","XP_013761301.1","XP_013760693.1","XP_013755219.1","XP_013758367.1","XP_013759839.1","XP_013759381.1","XP_013762616.1","XP_013757326.1","XP_013760498.1","XP_013758036.1","XP_013761138.1","XP_013762839.1","XP_013759857.1","XP_013757049.1","XP_013758853.1","XP_013758124.1","XP_013753372.1"]}