{"hash":"1346612106718669128","title":"ER-Golgi protein trafficking and maturation","description":"The cluster is dominated by GO terms related to the secretory pathway: ER-to-Golgi vesicle transport, retrograde transport, general protein transport, and maturation/processing such as EGFR ligand maturation and membrane protein proteolysis. There are also signals of ER stress/unfolded protein response, which fit with protein maturation in the ER. A few developmental terms (wing/eye cell fate) may reflect tissue contexts where secretory trafficking is important, but the core theme ties to vesicle trafficking and maturation through the ER-Golgi axis.","confidence":"Medium","size":3,"edges":1,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"XP_005535059.1","go_terms":["GO:1904211","GO:0032815","GO:0038005","GO:0042676","GO:0048515","GO:0035311","GO:0034620"]},{"accession":"XP_005536570.1","go_terms":[]},{"accession":"XP_005536440.1","go_terms":["GO:0006888","GO:0042147","GO:0015031"]}],"graph":[["XP_005536570.1","XP_005536440.1",0.72]],"all_go_terms":{"GO:0035311":1,"GO:0048515":1,"GO:0038005":1,"GO:1904211":1,"GO:0042676":1,"GO:0034620":1,"GO:0032815":1,"GO:0006888":1,"GO:0015031":1,"GO:0042147":1},"recipe_readded":["XP_005539027.1","XP_005539391.1","XP_005535575.1","XP_005535159.1","XP_005538086.1","XP_005535163.1"]}