{"hash":"1431157086698452524","title":"ER protein folding and stress-induced translation regulation","description":"The top GO terms cluster around endoplasmic reticulum proteostasis: protein folding in the ER, chaperone-assisted refolding, and regulation of translation initiation in response to ER stress, pointing to unfolded protein response and quality control. Additional terms touch on redox homeostasis and protein complex assembly, which can relate to ER-related folding and maturation processes. Some terms (mesoderm formation, DNA replication) seem less connected and may reflect broader annotations or incidental associations in this set. Overall, the cluster seems centered on ER proteostasis and stress response rather than a single, completely uniform function.","confidence":"Medium","size":9,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_002503935.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_002506701.1","go_terms":[]},{"accession":"XP_002499871.1","go_terms":["GO:0045190","GO:0009688","GO:0044810","GO:0090282","GO:0090419","GO:0009190","GO:0033624","GO:0021693","GO:1903468","GO:0034244","GO:1990705","GO:0032487","GO:0051237","GO:0070535","GO:0035196","GO:0072383","GO:0007249","GO:0090055","GO:0021685","GO:1905150"]},{"accession":"XP_002501868.1","go_terms":[]},{"accession":"XP_002501967.1","go_terms":["GO:0048235","GO:0040015","GO:0050873"]},{"accession":"XP_002503363.1","go_terms":["GO:0050689","GO:0071360","GO:0071357","GO:0045087","GO:0008277","GO:0051301","GO:0006336","GO:0001824","GO:0006335"]},{"accession":"XP_002503815.1","go_terms":["GO:0071480","GO:0000304","GO:0034620","GO:2001033","GO:0060136","GO:1900365","GO:1900462","GO:1990911","GO:1990910","GO:0033169","GO:0061408","GO:0070207","GO:1904843","GO:0071276","GO:0072738","GO:0001892","GO:0071280","GO:1900427","GO:1903936","GO:0043497","GO:0006351"]},{"accession":"XP_002504755.1","go_terms":[]},{"accession":"XP_002506376.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0090084":1,"GO:0070389":1,"GO:0097428":1,"GO:0036494":1,"GO:0051259":1,"GO:0032781":1,"GO:0001707":1,"GO:0006260":1,"GO:0045454":1,"GO:0034975":1,"GO:0071630":1,"GO:0009408":1,"GO:0006469":1,"GO:0035719":1,"GO:1900035":1,"GO:0006986":1,"GO:0031204":1,"GO:0006452":1,"GO:0070843":1,"GO:1901621":1,"GO:0006626":1,"GO:0006458":1,"GO:0046825":1,"GO:0071374":1,"GO:0030433":1,"GO:0090282":1,"GO:0009688":1,"GO:0034244":1,"GO:0045190":1,"GO:0090055":1,"GO:1905150":1,"GO:0035196":1,"GO:0051237":1,"GO:0044810":1,"GO:0009190":1,"GO:1903468":1,"GO:0007249":1,"GO:0072383":1,"GO:1990705":1,"GO:0021685":1,"GO:0070535":1,"GO:0021693":1,"GO:0090419":1,"GO:0032487":1,"GO:0033624":1,"GO:0050873":1,"GO:0040015":1,"GO:0048235":1,"GO:0001824":1,"GO:0045087":1,"GO:0071357":1,"GO:0050689":1,"GO:0006335":1,"GO:0051301":1,"GO:0008277":1,"GO:0071360":1,"GO:0006336":1,"GO:0043497":1,"GO:0071480":1,"GO:0060136":1,"GO:0001892":1,"GO:1904843":1,"GO:0071276":1,"GO:1990910":1,"GO:1900462":1,"GO:0034620":1,"GO:1990911":1,"GO:1903936":1,"GO:0070207":1,"GO:0071280":1,"GO:0006351":1,"GO:0072738":1,"GO:0061408":1,"GO:0033169":1,"GO:1900427":1,"GO:1900365":1,"GO:2001033":1,"GO:0000304":1},"recipe_readded":["XP_002502755.1","XP_002507775.1","XP_002505947.1","XP_002504494.1","XP_002500577.1","XP_002508530.1","XP_002501965.1","XP_002500316.1","XP_002499952.1","XP_002509392.1","XP_002507053.1","XP_002504823.1","XP_002506379.1","XP_002500816.1","XP_002499661.1","XP_002499848.1","XP_002501020.1","XP_002501745.1","XP_002502661.1","XP_002499699.1"]}