{"hash":"1025779943957888104","title":"Proteasome-Mediated Proteolysis and Cell Cycle Regulation","description":"The top GO terms cluster around proteolysis and mitotic control: proteasome core complex assembly, proteasomal ubiquitin-independent protein catabolic process, APC-dependent catabolic process, and negative regulation of G2/M transition, which together point to protein turnover governing cell-cycle progression. Other terms (salt stress, C-type lectin receptor signaling, Fc-epsilon signaling, viral process) suggest broader stress and signaling roles but do not undermine the central theme of proteostasis linked to cell-cycle regulation. Overall, these proteins seem to participate in proteolysis-related control of mitosis, with some accompanying signaling context.","confidence":"Medium","size":4,"edges":6,"triangles":4,"max_degree":3,"top_function":null,"members":[{"accession":"XP_002502796.1","go_terms":["GO:0006284","GO:0097510"]},{"accession":"XP_002501776.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0010043","GO:0009651","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0043488","GO:0006521","GO:0002479","GO:0046686","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0060071","GO:0010972","GO:0010950","GO:0002862","GO:0038095","GO:0010363","GO:0016579","GO:0010499","GO:0016032"]},{"accession":"XP_002508440.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0010043","GO:0009651","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0043488","GO:0006521","GO:0002479","GO:0046686","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0060071","GO:0010972","GO:0010950","GO:0002862","GO:0038095","GO:0010363","GO:0016579","GO:0010499","GO:0016032"]},{"accession":"XP_002507087.1","go_terms":["GO:0090263","GO:0038061","GO:0033209","GO:0051437","GO:0051436","GO:0061418","GO:0080129","GO:0006521","GO:0002223","GO:0090090","GO:0050852","GO:0031146","GO:0031145","GO:0002862","GO:0010972","GO:0060071","GO:0010499","GO:0016032","GO:0010043","GO:0009651","GO:0043488","GO:0002479","GO:0046686","GO:0010950","GO:0038095","GO:0010363","GO:0016579"]}],"graph":[["XP_002501776.1","XP_002502796.1",0.99],["XP_002501776.1","XP_002507087.1",0.989],["XP_002501776.1","XP_002508440.1",0.974],["XP_002508440.1","XP_002502796.1",0.921],["XP_002508440.1","XP_002507087.1",0.936],["XP_002507087.1","XP_002502796.1",0.961]],"all_go_terms":{"GO:0097510":1,"GO:0006284":1,"GO:0009651":3,"GO:0002223":3,"GO:0031145":3,"GO:0016032":3,"GO:0051437":3,"GO:0010499":3,"GO:0080129":3,"GO:0010972":3,"GO:0038095":3,"GO:0090090":3,"GO:0010950":3,"GO:0002862":3,"GO:0006521":3,"GO:0050852":3,"GO:0033209":3,"GO:0016579":3,"GO:0090263":3,"GO:0031146":3,"GO:0043488":3,"GO:0002479":3,"GO:0051436":3,"GO:0038061":3,"GO:0061418":3,"GO:0010043":3,"GO:0010363":3,"GO:0046686":3,"GO:0060071":3},"recipe_readded":[]}