{"hash":"909353058757874247","title":"ER Targeting and Unfolded Protein Response","description":"This cluster is dominated by GO terms linked to targeting proteins to membranes (SRP-dependent cotranslational targeting and post-translational targeting to membranes) and to protein quality control under stress (cellular response to unfolded protein, ER stress-related apoptotic signaling). The presence of terms regulating inclusion body assembly and negative regulation of heat response further supports a proteostasis/ER-stress theme. Some terms like DNA replication and karyogamy are peripheral, but the strongest theme centers on ER-associated protein targeting and stress responses.","confidence":"Medium","size":9,"edges":30,"triangles":48,"max_degree":8,"top_function":"DNA 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