{"hash":"1169593736732793987","title":"Retroviral Entry, Integration, and Latency","description":"The terms point to a retroviral lifecycle: entry into the host cell, penetration into the nucleus, RNA-templated DNA synthesis, DNA replication and recombination, and establishment of integrated proviral latency, with DNA integration as a key feature. The prominence of proviral latency and integration terms strongly supports a retrovirus interpretation, though some terms about host apoptosis and symbiont-related processes may reflect broader host\u2013virus interactions rather than core replication steps. Overall, this cluster is best described as retroviral entry and proviral integration with latency.","confidence":"High","size":9,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_019858961.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"XP_003385693.1","go_terms":["GO:0019677","GO:0015938","GO:0046067","GO:0046656","GO:0006203","GO:1901909","GO:1901907","GO:2000233","GO:0006382","GO:0046709","GO:0006281","GO:0015967","GO:0009240","GO:0046057","GO:2000781","GO:0034656","GO:0045337","GO:0016077","GO:0050992","GO:0071544","GO:1901639","GO:1901911"]},{"accession":"XP_003382570.1","go_terms":["GO:0010312","GO:0070574","GO:0060173","GO:0006882","GO:0006831","GO:0006830","GO:0044749","GO:0034224","GO:1903615"]},{"accession":"XP_003384658.2","go_terms":["GO:0008033","GO:0070156","GO:0006412"]},{"accession":"XP_019863093.1","go_terms":["GO:0055007","GO:0009791","GO:0009409","GO:0046949","GO:0042594","GO:0019254","GO:0042758","GO:0045329","GO:0007507","GO:0006574","GO:0033539","GO:0006552","GO:0033540","GO:0005978","GO:0006111","GO:0001889","GO:0051793","GO:0018896","GO:0006694","GO:0019439","GO:0055114"]},{"accession":"XP_019856014.1","go_terms":["GO:0000963","GO:0045333","GO:1902775","GO:1901259"]},{"accession":"XP_019854197.1","go_terms":[]},{"accession":"XP_003383498.1","go_terms":["GO:0006217","GO:0009972","GO:0002100","GO:0019858","GO:0009231","GO:0046109","GO:0046677","GO:0044206","GO:0006147"]},{"accession":"XP_019862917.1","go_terms":["GO:0048678","GO:0019381","GO:0043419","GO:0007411","GO:0044205","GO:0051491","GO:0007010","GO:0019700","GO:0048666","GO:1900817","GO:1904530","GO:0009442","GO:0030516","GO:0005975","GO:0007420","GO:0006046","GO:0019262","GO:0019556","GO:0019557","GO:0006207","GO:0051017","GO:0006147","GO:0006146","GO:0006209"]}],"graph":[],"all_go_terms":{"GO:0075713":1,"GO:0046718":1,"GO:0006260":1,"GO:0006310":1,"GO:0015074":1,"GO:0039651":1,"GO:1903704":1,"GO:0006278":1,"GO:0075732":1,"GO:0009240":1,"GO:0015938":1,"GO:0046057":1,"GO:1901907":1,"GO:0034656":1,"GO:0006382":1,"GO:1901909":1,"GO:0046067":1,"GO:0019677":1,"GO:0045337":1,"GO:2000781":1,"GO:0050992":1,"GO:0006203":1,"GO:0016077":1,"GO:0046656":1,"GO:0046709":1,"GO:1901911":1,"GO:0071544":1,"GO:0015967":1,"GO:2000233":1,"GO:1901639":1,"GO:0006281":1,"GO:0006831":1,"GO:1903615":1,"GO:0034224":1,"GO:0070574":1,"GO:0006882":1,"GO:0006830":1,"GO:0060173":1,"GO:0010312":1,"GO:0044749":1,"GO:0070156":1,"GO:0006412":1,"GO:0008033":1,"GO:0006552":1,"GO:0033540":1,"GO:0055114":1,"GO:0055007":1,"GO:0033539":1,"GO:0009409":1,"GO:0042758":1,"GO:0005978":1,"GO:0006111":1,"GO:0006694":1,"GO:0007507":1,"GO:0019254":1,"GO:0019439":1,"GO:0009791":1,"GO:0018896":1,"GO:0006574":1,"GO:0001889":1,"GO:0046949":1,"GO:0045329":1,"GO:0042594":1,"GO:0051793":1,"GO:1901259":1,"GO:1902775":1,"GO:0000963":1,"GO:0045333":1,"GO:0009231":1,"GO:0044206":1,"GO:0002100":1,"GO:0019858":1,"GO:0009972":1,"GO:0046677":1,"GO:0006217":1,"GO:0046109":1,"GO:0006147":2,"GO:0006046":1,"GO:0044205":1,"GO:0019556":1,"GO:0007420":1,"GO:0006146":1,"GO:0005975":1,"GO:0048678":1,"GO:0019262":1,"GO:0009442":1,"GO:0019557":1,"GO:0006209":1,"GO:0048666":1,"GO:0043419":1,"GO:0007010":1,"GO:0019381":1,"GO:0007411":1,"GO:0051017":1,"GO:0051491":1,"GO:0030516":1,"GO:1904530":1,"GO:1900817":1,"GO:0019700":1,"GO:0006207":1},"recipe_readded":["XP_019848768.1","XP_003391233.1","XP_003384054.1"]}