{"hash":"555506205998199972","title":"Lysosomal glycosylation and secretion","description":"This cluster centers on lysosome biology and glycosylation: lysosome organization, secretion of lysosomal enzymes, and N-/O-glycosylation pathways, with UDP-glucose metabolism supporting glycan assembly. Together these suggest roles in glycoprotein maturation and trafficking to lysosomes or secretory pathways, with some links to extracellular matrix and immune-related secretory processes.","confidence":"High","size":12,"edges":55,"triangles":135,"max_degree":11,"top_function":"lysosome organization","members":[{"accession":"XP_638302.1","go_terms":["GO:0090503","GO:0000288","GO:0033962","GO:0035195","GO:0061014","GO:0000290","GO:0045944","GO:0043928","GO:0000289"]},{"accession":"XP_638756.1","go_terms":["GO:0009247","GO:0009405","GO:0097502","GO:0008654","GO:0036108","GO:0016266","GO:0030244","GO:0019350","GO:0071555","GO:0006011","GO:0018242","GO:0018243","GO:0030213","GO:0002378","GO:0007631","GO:0009413","GO:0010125","GO:0009414","GO:0072708","GO:0071793","GO:0009744","GO:0006490","GO:0005978","GO:0005985","GO:0010555","GO:0033577","GO:0006506","GO:0006006","GO:0019252"]},{"accession":"XP_639192.1","go_terms":["GO:0009272","GO:0009252","GO:0045226","GO:0009103","GO:0000902","GO:0071555","GO:0006011","GO:0019252","GO:0009243","GO:0009245","GO:0009244","GO:0008360","GO:0000032","GO:0006048","GO:0009298","GO:0005978","GO:0019305","GO:1905606","GO:2000507","GO:0001732","GO:0001541","GO:1905696","GO:0042256","GO:0002183","GO:1905612","GO:1905618","GO:0010801","GO:0014003","GO:0014002","GO:0001731","GO:0043547","GO:1905537","GO:0045947","GO:0046677","GO:0005989","GO:0019877","GO:0006535","GO:0009089","GO:0045228"]},{"accession":"XP_642752.1","go_terms":["GO:0033320","GO:0009258","GO:0006730","GO:0009245","GO:0071951","GO:0046677","GO:0006189","GO:0006413","GO:0009103"]},{"accession":"XP_644158.1","go_terms":["GO:0046835","GO:0033299","GO:0016256","GO:0007040"]},{"accession":"XP_637479.1","go_terms":["GO:0035269","GO:0016266","GO:0010289","GO:0006012","GO:0005978","GO:0071555","GO:0010192","GO:0043403","GO:0010417","GO:0009834"]},{"accession":"XP_641985.1","go_terms":["GO:0036108","GO:0016266","GO:0030244","GO:0019350","GO:0071555","GO:0006011","GO:0018242","GO:0018243","GO:0030213","GO:0002378"]},{"accession":"XP_642558.1","go_terms":["GO:0046835","GO:0033299","GO:0016256","GO:0007040"]},{"accession":"XP_644027.1","go_terms":["GO:0046835","GO:0033299","GO:0016256","GO:0007040"]},{"accession":"XP_646677.1","go_terms":["GO:0006049","GO:0006486","GO:0035010","GO:0035284"]},{"accession":"XP_637636.1","go_terms":["GO:0046835","GO:0033299","GO:0016256","GO:0007040"]},{"accession":"XP_636759.1","go_terms":["GO:0036108","GO:0016266","GO:0030244","GO:0019350","GO:0071555","GO:0006011","GO:0018242","GO:0018243","GO:0030213","GO:0002378"]}],"graph":[["XP_642752.1","XP_636759.1",0.794],["XP_642752.1","XP_637479.1",0.852],["XP_642752.1","XP_637636.1",0.716],["XP_642752.1","XP_639192.1",0.703],["XP_642752.1","XP_642558.1",0.589],["XP_642752.1","XP_644027.1",0.767],["XP_638756.1","XP_636759.1",0.654],["XP_638756.1","XP_637479.1",0.788],["XP_638756.1","XP_637636.1",0.769],["XP_638756.1","XP_639192.1",0.538],["XP_638756.1","XP_641985.1",0.75],["XP_638756.1","XP_642558.1",0.776],["XP_638756.1","XP_644027.1",0.729],["XP_638756.1","XP_646677.1",0.674],["XP_646677.1","XP_636759.1",0.681],["XP_646677.1","XP_637479.1",0.818],["XP_646677.1","XP_637636.1",0.802],["XP_646677.1","XP_638302.1",0.6],["XP_646677.1","XP_639192.1",0.707],["XP_646677.1","XP_641985.1",0.784],["XP_646677.1","XP_642558.1",0.806],["XP_646677.1","XP_644027.1",0.788],["XP_646677.1","XP_644158.1",0.717],["XP_644158.1","XP_636759.1",0.683],["XP_644158.1","XP_637479.1",0.729],["XP_644158.1","XP_637636.1",0.714],["XP_644158.1","XP_639192.1",0.728],["XP_644158.1","XP_642558.1",0.683],["XP_644158.1","XP_644027.1",0.702],["XP_637479.1","XP_636759.1",0.829],["XP_637479.1","XP_637636.1",0.781],["XP_637479.1","XP_638302.1",0.686],["XP_637479.1","XP_639192.1",0.873],["XP_637479.1","XP_644027.1",0.817],["XP_637479.1","XP_641985.1",0.847],["XP_637479.1","XP_642558.1",0.819],["XP_638302.1","XP_637636.1",0.645],["XP_638302.1","XP_639192.1",0.76],["XP_638302.1","XP_642558.1",0.609],["XP_638302.1","XP_644027.1",0.669],["XP_644027.1","XP_636759.1",0.725],["XP_644027.1","XP_637636.1",0.799],["XP_644027.1","XP_639192.1",0.84],["XP_644027.1","XP_641985.1",0.691],["XP_644027.1","XP_642558.1",0.767],["XP_639192.1","XP_636759.1",0.75],["XP_639192.1","XP_637636.1",0.843],["XP_639192.1","XP_641985.1",0.625],["XP_639192.1","XP_642558.1",0.838],["XP_636759.1","XP_637636.1",0.764],["XP_636759.1","XP_641985.1",0.721],["XP_636759.1","XP_642558.1",0.719],["XP_642558.1","XP_637636.1",0.801],["XP_642558.1","XP_641985.1",0.724],["XP_641985.1","XP_637636.1",0.726]],"all_go_terms":{"GO:0000288":1,"GO:0033962":1,"GO:0035195":1,"GO:0061014":1,"GO:0000289":1,"GO:0000290":1,"GO:0043928":1,"GO:0090503":1,"GO:0045944":1,"GO:0030213":3,"GO:0007631":1,"GO:0016266":4,"GO:0009405":1,"GO:0006490":1,"GO:0002378":3,"GO:0010125":1,"GO:0018243":3,"GO:0019350":3,"GO:0019252":2,"GO:0071793":1,"GO:0005978":3,"GO:0006506":1,"GO:0072708":1,"GO:0071555":5,"GO:0018242":3,"GO:0006006":1,"GO:0009744":1,"GO:0036108":3,"GO:0008654":1,"GO:0009247":1,"GO:0009414":1,"GO:0005985":1,"GO:0033577":1,"GO:0030244":3,"GO:0010555":1,"GO:0097502":1,"GO:0009413":1,"GO:0006011":4,"GO:0008360":1,"GO:0014003":1,"GO:0005989":1,"GO:0045947":1,"GO:0000032":1,"GO:0001731":1,"GO:1905696":1,"GO:0014002":1,"GO:0009243":1,"GO:0001732":1,"GO:0009298":1,"GO:1905537":1,"GO:0043547":1,"GO:0009244":1,"GO:0009089":1,"GO:0019305":1,"GO:1905612":1,"GO:0009252":1,"GO:2000507":1,"GO:0019877":1,"GO:0006535":1,"GO:0006048":1,"GO:0010801":1,"GO:0046677":2,"GO:0009245":2,"GO:1905618":1,"GO:0002183":1,"GO:0001541":1,"GO:0009272":1,"GO:0042256":1,"GO:0009103":2,"GO:0045226":1,"GO:0000902":1,"GO:0045228":1,"GO:1905606":1,"GO:0006189":1,"GO:0033320":1,"GO:0006413":1,"GO:0009258":1,"GO:0071951":1,"GO:0006730":1,"GO:0033299":4,"GO:0046835":4,"GO:0007040":4,"GO:0016256":4,"GO:0010192":1,"GO:0035269":1,"GO:0006012":1,"GO:0009834":1,"GO:0043403":1,"GO:0010417":1,"GO:0010289":1,"GO:0006486":1,"GO:0006049":1,"GO:0035010":1,"GO:0035284":1},"recipe_readded":[]}