{"hash":"1082227962825911184","title":"Endocytic Receptor Trafficking and Lysosome Targeting","description":"These proteins appear linked to internalization of cell-surface receptors, trafficking through endosomes toward lysosomal compartments, and associated signaling pathways (receptor signaling, integrin, VEGF). The GO terms include receptor internalization, protein localization to lysosome, endosome-to-melanosome transport, and receptor-mediated interactions, suggesting a cohesive role in endocytic trafficking coupled with signaling.","confidence":"Medium","size":14,"edges":43,"triangles":60,"max_degree":12,"top_function":null,"members":[{"accession":"XP_640285.1","go_terms":[]},{"accession":"XP_637817.1","go_terms":[]},{"accession":"XP_637818.1","go_terms":[]},{"accession":"XP_638769.1","go_terms":[]},{"accession":"XP_642698.1","go_terms":[]},{"accession":"XP_644142.1","go_terms":[]},{"accession":"XP_646438.1","go_terms":[]},{"accession":"XP_646377.1","go_terms":["GO:0030886","GO:1901223","GO:0007166","GO:0030913","GO:0046813","GO:0045747","GO:0043128","GO:0014005","GO:0035646","GO:2001046","GO:0007601","GO:1904352","GO:0061462","GO:0060219","GO:2000680","GO:0061298","GO:0031623","GO:0071404","GO:0090528","GO:2000145","GO:1900746"]},{"accession":"XP_639925.1","go_terms":[]},{"accession":"XP_646374.2","go_terms":["GO:0030886","GO:1901223","GO:0007166","GO:0030913","GO:0046813","GO:0045747","GO:0043128","GO:0014005","GO:0035646","GO:2001046","GO:0007601","GO:1904352","GO:0061462","GO:0060219","GO:2000680","GO:0061298","GO:0031623","GO:0071404","GO:0090528","GO:2000145","GO:1900746"]},{"accession":"XP_644055.1","go_terms":[]},{"accession":"XP_646691.1","go_terms":[]},{"accession":"XP_638768.1","go_terms":[]},{"accession":"XP_646364.1","go_terms":["GO:0030886","GO:1901223","GO:0007166","GO:0030913","GO:0046813","GO:0045747","GO:0043128","GO:0014005","GO:0035646","GO:2001046","GO:0007601","GO:1904352","GO:0061462","GO:0060219","GO:2000680","GO:0061298","GO:0031623","GO:0071404","GO:0090528","GO:2000145","GO:1900746"]}],"graph":[["XP_646377.1","XP_638768.1",0.549],["XP_646377.1","XP_638769.1",0.62],["XP_646377.1","XP_639925.1",0.549],["XP_646377.1","XP_644055.1",0.733],["XP_646377.1","XP_644142.1",0.855],["XP_646377.1","XP_646364.1",0.796],["XP_646377.1","XP_646374.2",0.814],["XP_640285.1","XP_642698.1",0.658],["XP_640285.1","XP_644142.1",0.643],["XP_638769.1","XP_638768.1",0.534],["XP_638769.1","XP_646691.1",0.536],["XP_638769.1","XP_646364.1",0.613],["XP_638769.1","XP_646374.2",0.681],["XP_638769.1","XP_644055.1",0.586],["XP_637818.1","XP_646691.1",0.62],["XP_637818.1","XP_646374.2",0.592],["XP_646438.1","XP_642698.1",0.577],["XP_646438.1","XP_646374.2",0.507],["XP_646438.1","XP_646691.1",0.756],["XP_639925.1","XP_644055.1",0.57],["XP_639925.1","XP_644142.1",0.706],["XP_639925.1","XP_646364.1",0.678],["XP_639925.1","XP_646374.2",0.714],["XP_638768.1","XP_646691.1",0.532],["XP_638768.1","XP_646364.1",0.66],["XP_638768.1","XP_646374.2",0.743],["XP_638768.1","XP_644142.1",0.535],["XP_642698.1","XP_646691.1",0.802],["XP_642698.1","XP_646364.1",0.742],["XP_642698.1","XP_646374.2",0.699],["XP_642698.1","XP_644142.1",0.648],["XP_646691.1","XP_644055.1",0.521],["XP_646691.1","XP_644142.1",0.56],["XP_646691.1","XP_646364.1",0.588],["XP_646691.1","XP_646374.2",0.652],["XP_637817.1","XP_646374.2",0.775],["XP_637817.1","XP_644142.1",0.694],["XP_644055.1","XP_646364.1",0.663],["XP_644055.1","XP_646374.2",0.788],["XP_644055.1","XP_644142.1",0.677],["XP_646364.1","XP_644142.1",0.799],["XP_646364.1","XP_646374.2",0.821],["XP_646374.2","XP_644142.1",0.781]],"all_go_terms":{"GO:0035646":3,"GO:0043128":3,"GO:0090528":3,"GO:0031623":3,"GO:0061462":3,"GO:0046813":3,"GO:0071404":3,"GO:0007166":3,"GO:2001046":3,"GO:1900746":3,"GO:2000680":3,"GO:1904352":3,"GO:0060219":3,"GO:2000145":3,"GO:1901223":3,"GO:0045747":3,"GO:0061298":3,"GO:0030886":3,"GO:0014005":3,"GO:0030913":3,"GO:0007601":3},"recipe_readded":[]}