{"hash":"1001206177398039254","title":"Lipid metabolism and GPCR signaling","description":"This cluster is characterized by lipid-related processes, notably sphingomyelin catabolic process and lysobisphosphatidic acid metabolic process, suggesting a theme of sphingolipid/lysosomal lipid turnover. It also includes an adenylate cyclase-inhibiting GPCR signaling term, pointing to GPCR-mediated regulation of cAMP. While there are some tissue-specific terms related to prostate gland development, the dominant signals tie lipids to signaling pathways, making this a cohesive lipid-metabolism\u2013signaling cluster.","confidence":"Medium","size":21,"edges":9,"triangles":2,"max_degree":4,"top_function":null,"members":[{"accession":"XP_637449.1","go_terms":["GO:0060168","GO:0016311","GO:0050650","GO:0051516","GO:2001311","GO:0016036","GO:0071454","GO:0032958","GO:0006020","GO:0006144","GO:0010909"]},{"accession":"XP_637600.1","go_terms":["GO:0060736","GO:1903206","GO:0007193","GO:0006685","GO:0060742"]},{"accession":"XP_638006.1","go_terms":[]},{"accession":"XP_640129.1","go_terms":[]},{"accession":"XP_641706.1","go_terms":[]},{"accession":"XP_643297.1","go_terms":[]},{"accession":"XP_645895.1","go_terms":["GO:0032805","GO:0032804","GO:1905601","GO:0032802","GO:0032902","GO:0030435","GO:0034230","GO:1905596","GO:0030070","GO:0007323","GO:0007354","GO:0002001","GO:1905598","GO:0090472","GO:0010989","GO:0001920"]},{"accession":"XP_647139.1","go_terms":[]},{"accession":"XP_637113.1","go_terms":[]},{"accession":"XP_643992.1","go_terms":[]},{"accession":"XP_646711.1","go_terms":[]},{"accession":"XP_641613.1","go_terms":["GO:0060736","GO:1903206","GO:0007193","GO:0006685","GO:0060742","GO:0006665"]},{"accession":"XP_637119.1","go_terms":[]},{"accession":"XP_638467.1","go_terms":[]},{"accession":"XP_644377.1","go_terms":[]},{"accession":"XP_646785.1","go_terms":[]},{"accession":"XP_638868.1","go_terms":[]},{"accession":"XP_642966.1","go_terms":[]},{"accession":"XP_643441.1","go_terms":[]},{"accession":"XP_642925.1","go_terms":[]},{"accession":"XP_644032.1","go_terms":[]}],"graph":[["XP_637600.1","XP_637119.1",0.526],["XP_637600.1","XP_644032.1",0.567],["XP_646785.1","XP_637449.1",0.506],["XP_646785.1","XP_644032.1",0.516],["XP_646785.1","XP_647139.1",0.663],["XP_643297.1","XP_637449.1",0.664],["XP_642925.1","XP_647139.1",0.518],["XP_644032.1","XP_637449.1",0.531],["XP_644032.1","XP_647139.1",0.665]],"all_go_terms":{"GO:0016036":1,"GO:0010909":1,"GO:0016311":1,"GO:2001311":1,"GO:0051516":1,"GO:0006020":1,"GO:0071454":1,"GO:0032958":1,"GO:0050650":1,"GO:0006144":1,"GO:0060168":1,"GO:0006685":2,"GO:0060736":2,"GO:1903206":2,"GO:0060742":2,"GO:0007193":2,"GO:0010989":1,"GO:0032902":1,"GO:0007354":1,"GO:0007323":1,"GO:1905598":1,"GO:1905601":1,"GO:0030070":1,"GO:0090472":1,"GO:0032802":1,"GO:0032805":1,"GO:1905596":1,"GO:0001920":1,"GO:0034230":1,"GO:0002001":1,"GO:0032804":1,"GO:0030435":1,"GO:0006665":1},"recipe_readded":["XP_642950.2","XP_643842.1","XP_636345.2","XP_637673.1","XP_638179.1","XP_644066.1","XP_643144.1","XP_637572.1","XP_647574.1","XP_646296.1","XP_645874.1","XP_642767.1","XP_640572.1","XP_639096.1","XP_646686.1","XP_644045.1","XP_638165.1","XP_641270.1","XP_642415.1","XP_643835.1"]}