{"hash":"999337291948052439","title":"DNA damage response\u2013linked transcription and translation control","description":"The cluster is dominated by translation (GO:0006412) and ribosomal biogenesis terms, with related transcription elongation and regulation annotations (GO:0031564, GO:0032784, GO:0006354). It also includes DNA damage response signals mediated by p53 (GO:0006977, GO:1902167, GO:1902164) and gamma radiation response (GO:0071480), suggesting coordinated regulation of gene expression and protein synthesis in response to DNA damage. Together, these terms point to a functional theme of managing transcription and translation under DNA-damage stress.","confidence":"High","size":15,"edges":68,"triangles":185,"max_degree":13,"top_function":null,"members":[{"accession":"NP_001011013.1","go_terms":["GO:2000271","GO:0045671","GO:0021542","GO:0060213","GO:0008306","GO:0030514","GO:0045778","GO:0045603","GO:0060212","GO:0045663","GO:0017148","GO:0035914","GO:0021954","GO:2000178","GO:0045668","GO:0007184"]},{"accession":"NP_001016534.1","go_terms":["GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353","GO:0045727","GO:0006412","GO:0006364","GO:0016236","GO:0051298","GO:0042256"]},{"accession":"NP_001011414.1","go_terms":["GO:0071549","GO:0006281","GO:0006412"]},{"accession":"NP_989119.1","go_terms":["GO:0061481","GO:0042274","GO:1905053","GO:0042254","GO:0000056","GO:0006412","GO:0006407"]},{"accession":"NP_001005122.1","go_terms":["GO:0042273","GO:0000055","GO:0006412"]},{"accession":"NP_001120075.1","go_terms":["GO:0071353","GO:0006412","GO:0000027"]},{"accession":"NP_001165147.1","go_terms":["GO:0002181","GO:0001576"]},{"accession":"XP_017951776.2","go_terms":["GO:0006450","GO:0034337","GO:0000462","GO:0033120","GO:0046677","GO:0000372","GO:0006412"]},{"accession":"NP_001005095.1","go_terms":["GO:0046898","GO:0046677","GO:0006412"]},{"accession":"NP_001005118.1","go_terms":["GO:0006450","GO:0006412"]},{"accession":"NP_001005134.1","go_terms":["GO:0006412"]},{"accession":"NP_001011030.1","go_terms":["GO:0042254","GO:0006412"]},{"accession":"NP_001016180.1","go_terms":["GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353","GO:0045727","GO:0006412"]},{"accession":"NP_001025612.1","go_terms":["GO:0071353","GO:0006412","GO:0000027"]},{"accession":"NP_001005100.1","go_terms":["GO:0002181"]}],"graph":[["NP_001005122.1","NP_001005095.1",0.71],["NP_001005122.1","NP_001005100.1",0.795],["NP_001005122.1","NP_001005118.1",0.825],["NP_001005122.1","NP_001005134.1",0.806],["NP_001005122.1","NP_001011030.1",0.789],["NP_001005122.1","NP_001011414.1",0.812],["NP_001005122.1","NP_001016180.1",0.805],["NP_001005122.1","NP_001016534.1",0.786],["NP_001005122.1","NP_001025612.1",0.772],["NP_001005122.1","NP_001120075.1",0.785],["NP_001005122.1","NP_001165147.1",0.698],["NP_001005122.1","NP_989119.1",0.806],["NP_001005122.1","XP_017951776.2",0.648],["NP_989119.1","NP_001005095.1",0.807],["NP_989119.1","NP_001005100.1",0.821],["NP_989119.1","NP_001005118.1",0.859],["NP_989119.1","NP_001005134.1",0.868],["NP_989119.1","NP_001011030.1",0.834],["NP_989119.1","NP_001011414.1",0.819],["NP_989119.1","NP_001016180.1",0.82],["NP_989119.1","NP_001016534.1",0.786],["NP_989119.1","NP_001025612.1",0.839],["NP_989119.1","NP_001120075.1",0.85],["NP_989119.1","NP_001165147.1",0.881],["NP_989119.1","XP_017951776.2",0.724],["NP_001120075.1","NP_001005095.1",0.771],["NP_001120075.1","NP_001005100.1",0.811],["NP_001120075.1","NP_001005118.1",0.793],["NP_001120075.1","NP_001005134.1",0.721],["NP_001120075.1","NP_001011030.1",0.553],["NP_001120075.1","NP_001016534.1",0.628],["NP_001120075.1","NP_001025612.1",0.533],["NP_001120075.1","XP_017951776.2",0.665],["NP_001005095.1","NP_001005100.1",0.839],["NP_001005095.1","NP_001005118.1",0.695],["NP_001005095.1","NP_001005134.1",0.81],["NP_001005095.1","NP_001011030.1",0.749],["NP_001005095.1","NP_001011414.1",0.794],["NP_001005095.1","NP_001016180.1",0.781],["NP_001005095.1","NP_001016534.1",0.722],["NP_001005095.1","NP_001025612.1",0.792],["NP_001005095.1","NP_001165147.1",0.702],["NP_001005095.1","XP_017951776.2",0.612],["NP_001005100.1","NP_001005118.1",0.807],["NP_001005100.1","NP_001005134.1",0.824],["NP_001005100.1","NP_001011030.1",0.653],["NP_001005100.1","NP_001016180.1",0.812],["NP_001005100.1","NP_001016534.1",0.595],["NP_001005100.1","NP_001025612.1",0.829],["NP_001005118.1","NP_001005134.1",0.755],["NP_001005118.1","NP_001011030.1",0.679],["NP_001005118.1","NP_001016534.1",0.805],["NP_001005118.1","NP_001025612.1",0.795],["NP_001005118.1","XP_017951776.2",0.728],["NP_001025612.1","NP_001005134.1",0.804],["NP_001025612.1","NP_001011030.1",0.613],["NP_001025612.1","NP_001016180.1",0.639],["NP_001025612.1","NP_001016534.1",0.693],["NP_001025612.1","XP_017951776.2",0.647],["NP_001005134.1","NP_001011030.1",0.554],["NP_001005134.1","NP_001016534.1",0.629],["NP_001005134.1","XP_017951776.2",0.715],["NP_001011030.1","NP_001016534.1",0.711],["NP_001011030.1","XP_017951776.2",0.663],["XP_017951776.2","NP_001011414.1",0.511],["XP_017951776.2","NP_001016180.1",0.628],["XP_017951776.2","NP_001016534.1",0.75],["NP_001016180.1","NP_001016534.1",0.819]],"all_go_terms":{"GO:0035914":1,"GO:2000178":1,"GO:0030514":1,"GO:0060213":1,"GO:0045778":1,"GO:0017148":1,"GO:0045603":1,"GO:0021954":1,"GO:0045663":1,"GO:0007184":1,"GO:0021542":1,"GO:0045671":1,"GO:2000271":1,"GO:0008306":1,"GO:0045668":1,"GO:0060212":1,"GO:0042256":1,"GO:0006977":2,"GO:1902167":2,"GO:0031564":2,"GO:0032784":2,"GO:1902164":2,"GO:0006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