{"hash":"573916721741953466","title":"Ribosome Biogenesis and Translation Machinery","description":"Based on GO terms, the cluster centers on ribosome-related processes and translation: GO:0006412 (translation) and GO:0042254 (ribosome biogenesis) are the top terms. Additional terms point to RNA modification and snoRNP assembly (box C/D snoRNP assembly), as well as RNA processing activities like pseudouridine synthesis of snRNA and rRNA, indicating a cohesive group involved in ribosome function and maturation. A few signaling terms (MAPK cascades) are present but likely less representative of the core function.","confidence":"High","size":13,"edges":78,"triangles":286,"max_degree":12,"top_function":"ribosome biogenesis","members":[{"accession":"NP_988989.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"NP_989067.1","go_terms":["GO:0032147","GO:0042254","GO:0006614","GO:0071353","GO:0002181","GO:0000027"]},{"accession":"NP_989068.1","go_terms":["GO:0046718","GO:0000028","GO:0000461","GO:0007155","GO:0000447","GO:0006412","GO:0006407","GO:0042254"]},{"accession":"NP_001005110.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"NP_001016765.1","go_terms":["GO:0042254","GO:0000028","GO:0000461","GO:0000447","GO:0006412","GO:0006407"]},{"accession":"NP_001123667.1","go_terms":["GO:0031564","GO:0010587","GO:1902219","GO:0031054","GO:0070934","GO:0060567","GO:1901724","GO:0006351"]},{"accession":"NP_001005106.1","go_terms":["GO:0031564","GO:0000462","GO:0006412"]},{"accession":"NP_001007869.1","go_terms":["GO:0045903","GO:0042254","GO:0006412","GO:1990145","GO:0046677","GO:0006407"]},{"accession":"NP_001008435.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]},{"accession":"NP_001005113.1","go_terms":["GO:0006412","GO:0000462","GO:0006413","GO:0001649"]},{"accession":"NP_988912.1","go_terms":["GO:0045727","GO:0006412","GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353"]},{"accession":"NP_001017041.1","go_terms":["GO:0010458","GO:0042273","GO:0060041","GO:0032781","GO:1902626","GO:0021554","GO:0007093","GO:0031290","GO:0006412","GO:0000027"]},{"accession":"NP_001072159.1","go_terms":["GO:0000185","GO:2000623","GO:0031118","GO:0031120","GO:0046330","GO:0007338","GO:0000470","GO:0048025","GO:0042254","GO:0001682","GO:1900745","GO:1904571","GO:0000492","GO:0006412"]}],"graph":[["NP_001005106.1","NP_001005110.1",0.722],["NP_001005106.1","NP_001005113.1",0.854],["NP_001005106.1","NP_001007869.1",0.783],["NP_001005106.1","NP_001008435.1",0.824],["NP_001005106.1","NP_001016765.1",0.8],["NP_001005106.1","NP_001017041.1",0.831],["NP_001005106.1","NP_001072159.1",0.819],["NP_001005106.1","NP_001123667.1",0.766],["NP_001005106.1","NP_988912.1",0.797],["NP_001005106.1","NP_988989.1",0.734],["NP_001005106.1","NP_989067.1",0.794],["NP_001005106.1","NP_989068.1",0.714],["NP_001005110.1","NP_001005113.1",0.845],["NP_001005110.1","NP_001007869.1",0.842],["NP_001005110.1","NP_001008435.1",0.786],["NP_001005110.1","NP_001016765.1",0.812],["NP_001005110.1","NP_001017041.1",0.801],["NP_001005110.1","NP_001072159.1",0.824],["NP_001005110.1","NP_001123667.1",0.8],["NP_001005110.1","NP_988912.1",0.85],["NP_001005110.1","NP_988989.1",0.735],["NP_001005110.1","NP_989067.1",0.785],["NP_001005110.1","NP_989068.1",0.855],["NP_989067.1","NP_001005113.1",0.782],["NP_989067.1","NP_001007869.1",0.769],["NP_989067.1","NP_001008435.1",0.759],["NP_989067.1","NP_001016765.1",0.796],["NP_989067.1","NP_001017041.1",0.766],["NP_989067.1","NP_001072159.1",0.775],["NP_989067.1","NP_001123667.1",0.757],["NP_989067.1","NP_988912.1",0.803],["NP_989067.1","NP_988989.1",0.749],["NP_989067.1","NP_989068.1",0.824],["NP_001005113.1","NP_001007869.1",0.753],["NP_001005113.1","NP_001008435.1",0.808],["NP_001005113.1","NP_001016765.1",0.819],["NP_001005113.1","NP_001017041.1",0.813],["NP_001005113.1","NP_001072159.1",0.811],["NP_001005113.1","NP_001123667.1",0.801],["NP_001005113.1","NP_988912.1",0.809],["NP_001005113.1","NP_988989.1",0.815],["NP_001005113.1","NP_989068.1",0.84],["NP_988912.1","NP_001007869.1",0.825],["NP_988912.1","NP_001008435.1",0.81],["NP_988912.1","NP_001016765.1",0.81],["NP_988912.1","NP_001017041.1",0.867],["NP_988912.1","NP_001072159.1",0.838],["NP_988912.1","NP_001123667.1",0.764],["NP_988912.1","NP_988989.1",0.817],["NP_988912.1","NP_989068.1",0.882],["NP_001008435.1","NP_001007869.1",0.78],["NP_001008435.1","NP_001016765.1",0.839],["NP_001008435.1","NP_001017041.1",0.76],["NP_001008435.1","NP_001072159.1",0.81],["NP_001008435.1","NP_001123667.1",0.822],["NP_001008435.1","NP_988989.1",0.815],["NP_001008435.1","NP_989068.1",0.872],["NP_001072159.1","NP_001007869.1",0.783],["NP_001072159.1","NP_001016765.1",0.774],["NP_001072159.1","NP_001017041.1",0.771],["NP_001072159.1","NP_001123667.1",0.79],["NP_001072159.1","NP_988989.1",0.842],["NP_001072159.1","NP_989068.1",0.859],["NP_988989.1","NP_001007869.1",0.825],["NP_988989.1","NP_001016765.1",0.864],["NP_988989.1","NP_001017041.1",0.785],["NP_988989.1","NP_001123667.1",0.797],["NP_988989.1","NP_989068.1",0.816],["NP_001007869.1","NP_001017041.1",0.797],["NP_001007869.1","NP_001016765.1",0.793],["NP_001007869.1","NP_989068.1",0.868],["NP_001007869.1","NP_001123667.1",0.791],["NP_001016765.1","NP_001017041.1",0.814],["NP_001016765.1","NP_001123667.1",0.812],["NP_001016765.1","NP_989068.1",0.835],["NP_001017041.1","NP_001123667.1",0.782],["NP_001017041.1","NP_989068.1",0.882],["NP_001123667.1","NP_989068.1",0.834]],"all_go_terms":{"GO:0046330":4,"GO:0042254":8,"GO:0000492":4,"GO:0031120":4,"GO:0000185":4,"GO:2000623":4,"GO:0031118":4,"GO:1904571":4,"GO:0006412":11,"GO:1900745":4,"GO:0001682":4,"GO:0000470":4,"GO:0007338":4,"GO:0048025":4,"GO:0032147":1,"GO:0002181":1,"GO:0071353":1,"GO:0006614":1,"GO:0000027":2,"GO:0000447":2,"GO:0006407":3,"GO:0046718":1,"GO:0000461":2,"GO:0007155":1,"GO:0000028":2,"GO:0031054":1,"GO:0060567":1,"GO:0031564":3,"GO:1901724":1,"GO:0070934":1,"GO:1902219":1,"GO:0010587":1,"GO:0006351":1,"GO:0000462":2,"GO:1990145":1,"GO:0045903":1,"GO:0046677":1,"GO:0006413":1,"GO:0001649":1,"GO:0006977":1,"GO:1902167":1,"GO:0032784":1,"GO:1902164":1,"GO:0006354":1,"GO:0045727":1,"GO:0071480":1,"GO:0006353":1,"GO:0042273":2,"GO:1904803":1,"GO:0010458":1,"GO:0021554":1,"GO:0007093":1,"GO:0032781":1,"GO:0060041":1,"GO:0031290":1,"GO:1902626":1},"recipe_readded":[]}