{"hash":"293206627312104561","title":"Ribosome biogenesis and translation machinery","description":"The cluster is heavily enriched for translation and ribosome biogenesis terms (translation, ribosome biogenesis, nucleolar rRNA transcription) and includes RNA polymerase activities (I/II/III) and nucleologenesis, suggesting proteins that drive ribosome production and associated nucleolar transcription/organization, with some ncRNA-related chromatin regulation points that align with nucleolar function.","confidence":"High","size":19,"edges":141,"triangles":575,"max_degree":18,"top_function":"ribosome biogenesis","members":[{"accession":"NP_001121521.1","go_terms":["GO:0042254","GO:0001172","GO:0017126","GO:0006366","GO:0031048","GO:0042797","GO:0042790"]},{"accession":"XP_002937598.2","go_terms":["GO:0042254","GO:0001172","GO:0017126","GO:0006366","GO:0031048","GO:0042797","GO:0042790"]},{"accession":"XP_017953345.1","go_terms":["GO:0006355","GO:0006351"]},{"accession":"NP_001016126.1","go_terms":["GO:0000470","GO:0006417","GO:0006412"]},{"accession":"NP_001017050.2","go_terms":["GO:0006431","GO:0006430","GO:0006432","GO:0051351","GO:0048514","GO:0008033","GO:0006412"]},{"accession":"NP_001072835.1","go_terms":["GO:0071042","GO:1990074","GO:0051306","GO:0016973","GO:0010587","GO:0070478","GO:0033621","GO:0071051","GO:0071035","GO:0071039","GO:0071038","GO:0060237","GO:0000465","GO:0000467","GO:0071028","GO:0070481","GO:0090502","GO:0070651","GO:0034427","GO:0090503"]},{"accession":"NP_001096223.1","go_terms":["GO:0032042","GO:0070150","GO:0006450","GO:0006433","GO:0006427","GO:0070159","GO:0015966","GO:0001701","GO:0022904","GO:0070584","GO:0006412","GO:0071897","GO:0016260","GO:0070158","GO:0097056","GO:0006435","GO:0070143","GO:0015970","GO:1903833","GO:0002181"]},{"accession":"XP_002936423.2","go_terms":["GO:0070126","GO:0006412"]},{"accession":"XP_031746236.1","go_terms":["GO:0015968","GO:0006415","GO:0006412","GO:0000027"]},{"accession":"NP_001017055.1","go_terms":["GO:0006412"]},{"accession":"NP_001121654.1","go_terms":["GO:0007605"]},{"accession":"XP_002938466.1","go_terms":["GO:0006412"]},{"accession":"XP_031757047.1","go_terms":["GO:1902306","GO:0033209","GO:0032088","GO:0048227","GO:1902072","GO:2000009"]},{"accession":"NP_001005120.2","go_terms":["GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353","GO:0045727","GO:0006412"]},{"accession":"NP_001016347.1","go_terms":["GO:0006259","GO:0090305","GO:0006412"]},{"accession":"XP_017949732.1","go_terms":["GO:0045903","GO:0042254","GO:0006412","GO:1990145","GO:0046677","GO:0006407"]},{"accession":"NP_001120107.1","go_terms":["GO:0046677","GO:0006412","GO:0046898"]},{"accession":"XP_031749153.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"NP_001107679.1","go_terms":["GO:0006412","GO:0000027"]}],"graph":[["NP_001107679.1","XP_017953345.1",0.784],["NP_001107679.1","XP_031746236.1",0.651],["NP_001107679.1","XP_031749153.1",0.893],["NP_001107679.1","XP_031757047.1",0.752],["NP_001107679.1","NP_001005120.2",0.802],["NP_001107679.1","NP_001016126.1",0.711],["NP_001107679.1","NP_001016347.1",0.783],["NP_001107679.1","NP_001017055.1",0.763],["NP_001107679.1","NP_001072835.1",0.501],["NP_001107679.1","NP_001096223.1",0.513],["NP_001107679.1","NP_001120107.1",0.823],["NP_001107679.1","NP_001121654.1",0.759],["NP_001107679.1","XP_002936423.2",0.734],["NP_001107679.1","XP_002937598.2",0.681],["NP_001107679.1","XP_002938466.1",0.735],["NP_001107679.1","XP_017949732.1",0.727],["XP_002938466.1","XP_017949732.1",0.664],["XP_002938466.1","XP_017953345.1",0.783],["XP_002938466.1","XP_031746236.1",0.509],["XP_002938466.1","XP_031749153.1",0.838],["XP_002938466.1","XP_031757047.1",0.762],["XP_002938466.1","NP_001005120.2",0.789],["XP_002938466.1","NP_001016126.1",0.726],["XP_002938466.1","NP_001016347.1",0.72],["XP_002938466.1","NP_001017050.2",0.818],["XP_002938466.1","NP_001017055.1",0.791],["XP_002938466.1","NP_001096223.1",0.676],["XP_002938466.1","NP_001120107.1",0.836],["XP_002938466.1","NP_001121521.1",0.707],["XP_002938466.1","NP_001121654.1",0.643],["XP_002938466.1","XP_002936423.2",0.786],["XP_002938466.1","XP_002937598.2",0.71],["NP_001121654.1","XP_017953345.1",0.709],["NP_001121654.1","XP_031746236.1",0.683],["NP_001121654.1","XP_031749153.1",0.828],["NP_001121654.1","XP_031757047.1",0.854],["NP_001121654.1","NP_001005120.2",0.683],["NP_001121654.1","NP_001016126.1",0.783],["NP_001121654.1","NP_001016347.1",0.689],["NP_001121654.1","NP_001017050.2",0.725],["NP_001121654.1","NP_001017055.1",0.764],["NP_001121654.1","NP_001072835.1",0.59],["NP_001121654.1","NP_001096223.1",0.661],["NP_001121654.1","NP_001120107.1",0.764],["NP_001121654.1","NP_001121521.1",0.724],["NP_001121654.1","XP_002936423.2",0.704],["NP_001121654.1","XP_002937598.2",0.747],["NP_001121654.1","XP_017949732.1",0.734],["NP_001072835.1","NP_001005120.2",0.648],["NP_001072835.1","NP_001016347.1",0.801],["NP_001072835.1","NP_001017050.2",0.605],["NP_001072835.1","NP_001017055.1",0.749],["NP_001072835.1","NP_001096223.1",0.599],["NP_001072835.1","XP_002937598.2",0.673],["NP_001072835.1","XP_002936423.2",0.679],["NP_001072835.1","NP_001121521.1",0.7],["NP_001072835.1","NP_001120107.1",0.538],["NP_001072835.1","XP_017949732.1",0.687],["NP_001072835.1","XP_031749153.1",0.69],["NP_001072835.1","XP_017953345.1",0.55],["XP_017953345.1","NP_001120107.1",0.664],["XP_017953345.1","NP_001121521.1",0.558],["XP_017953345.1","XP_002936423.2",0.726],["XP_017953345.1","XP_002937598.2",0.557],["XP_017953345.1","XP_017949732.1",0.728],["XP_017953345.1","XP_031746236.1",0.56],["XP_017953345.1","XP_031749153.1",0.776],["XP_017953345.1","XP_031757047.1",0.697],["XP_017953345.1","NP_001005120.2",0.647],["XP_017953345.1","NP_001016126.1",0.718],["XP_017953345.1","NP_001016347.1",0.738],["XP_017953345.1","NP_001017050.2",0.831],["XP_017953345.1","NP_001017055.1",0.758],["XP_017953345.1","NP_001096223.1",0.644],["XP_017949732.1","XP_002936423.2",0.733],["XP_017949732.1","XP_002937598.2",0.715],["XP_017949732.1","XP_031746236.1",0.797],["XP_017949732.1","XP_031749153.1",0.799],["XP_017949732.1","XP_031757047.1",0.769],["XP_017949732.1","NP_001005120.2",0.703],["XP_017949732.1","NP_001016126.1",0.706],["XP_017949732.1","NP_001016347.1",0.76],["XP_017949732.1","NP_001017050.2",0.781],["XP_017949732.1","NP_001017055.1",0.801],["XP_017949732.1","NP_001096223.1",0.719],["XP_017949732.1","NP_001120107.1",0.71],["XP_017949732.1","NP_001121521.1",0.665],["NP_001016347.1","NP_001005120.2",0.75],["NP_001016347.1","NP_001016126.1",0.712],["NP_001016347.1","NP_001017055.1",0.686],["NP_001016347.1","XP_002936423.2",0.792],["NP_001016347.1","XP_002937598.2",0.682],["NP_001016347.1","XP_031746236.1",0.604],["NP_001016347.1","XP_031749153.1",0.818],["NP_001016347.1","XP_031757047.1",0.751],["XP_031749153.1","NP_001120107.1",0.827],["XP_031749153.1","NP_001121521.1",0.796],["XP_031749153.1","XP_002936423.2",0.835],["XP_031749153.1","XP_002937598.2",0.808],["XP_031749153.1","XP_031746236.1",0.766],["XP_031749153.1","NP_001005120.2",0.835],["XP_031749153.1","NP_001016126.1",0.773],["XP_031749153.1","NP_001017055.1",0.834],["XP_031749153.1","NP_001096223.1",0.814],["NP_001120107.1","XP_031757047.1",0.754],["NP_001120107.1","NP_001016126.1",0.744],["NP_001120107.1","NP_001017055.1",0.622],["NP_001120107.1","NP_001096223.1",0.702],["NP_001120107.1","XP_002937598.2",0.702],["NP_001120107.1","XP_002936423.2",0.773],["NP_001016126.1","NP_001005120.2",0.726],["NP_001016126.1","NP_001096223.1",0.629],["NP_001016126.1","NP_001017050.2",0.602],["NP_001016126.1","NP_001017055.1",0.789],["NP_001016126.1","XP_002937598.2",0.614],["NP_001016126.1","XP_002936423.2",0.64],["NP_001016126.1","NP_001121521.1",0.665],["NP_001016126.1","XP_031757047.1",0.753],["NP_001016126.1","XP_031746236.1",0.582],["NP_001017055.1","NP_001005120.2",0.611],["NP_001017055.1","NP_001096223.1",0.677],["NP_001017055.1","NP_001121521.1",0.598],["NP_001017055.1","XP_002936423.2",0.781],["NP_001017055.1","XP_002937598.2",0.664],["NP_001017055.1","XP_031746236.1",0.576],["NP_001017055.1","XP_031757047.1",0.794],["XP_031746236.1","NP_001121521.1",0.559],["XP_031746236.1","XP_002936423.2",0.767],["XP_031746236.1","XP_002937598.2",0.604],["XP_031746236.1","NP_001005120.2",0.506],["NP_001005120.2","NP_001096223.1",0.55],["NP_001005120.2","XP_002936423.2",0.741],["NP_001005120.2","XP_031757047.1",0.69],["NP_001096223.1","NP_001121521.1",0.511],["NP_001096223.1","XP_002936423.2",0.69],["NP_001096223.1","XP_002937598.2",0.641],["XP_002937598.2","NP_001121521.1",0.684],["XP_002937598.2","XP_002936423.2",0.759],["XP_031757047.1","NP_001121521.1",0.646],["XP_031757047.1","NP_001017050.2",0.528],["NP_001121521.1","XP_002936423.2",0.731]],"all_go_terms":{"GO:0042797":2,"GO:0042254":3,"GO:0006366":2,"GO:0017126":2,"GO:0042790":2,"GO:0031048":2,"GO:0001172":3,"GO:0006351":1,"GO:0006355":1,"GO:0006412":13,"GO:0000470":1,"GO:0006417":1,"GO:0006431":1,"GO:0051351":1,"GO:0006430":1,"GO:0006432":1,"GO:0048514":1,"GO:0008033":1,"GO:0090503":1,"GO:0000465":1,"GO:0034427":1,"GO:0033621":1,"GO:0071038":1,"GO:0071051":1,"GO:0071042":1,"GO:0010587":1,"GO:0070481":1,"GO:0090502":1,"GO:0070651":1,"GO:0070478":1,"GO:0060237":1,"GO:1990074":1,"GO:0071039":1,"GO:0071035":1,"GO:0071028":1,"GO:0051306":1,"GO:0016973":1,"GO:0000467":1,"GO:0015966":1,"GO:0001701":1,"GO:0070143":1,"GO:0006435":1,"GO:0002181":1,"GO:0015970":1,"GO:0070158":1,"GO:0022904":1,"GO:0097056":1,"GO:0070159":1,"GO:0070150":1,"GO:0032042":1,"GO:0070584":1,"GO:0006450":1,"GO:0016260":1,"GO:0006433":1,"GO:0071897":1,"GO:1903833":1,"GO:0006427":1,"GO:0070126":1,"GO:0015968":1,"GO:0006415":2,"GO:0000027":2,"GO:0007605":1,"GO:0032088":1,"GO:0033209":1,"GO:2000009":1,"GO:1902072":1,"GO:1902306":1,"GO:0048227":1,"GO:0006977":1,"GO:1902167":1,"GO:0031564":1,"GO:0032784":1,"GO:1902164":1,"GO:0006354":1,"GO:0045727":1,"GO:0071480":1,"GO:0006353":1,"GO:0042273":1,"GO:1904803":1,"GO:0006259":1,"GO:0090305":1,"GO:0006407":1,"GO:1990145":1,"GO:0045903":2,"GO:0046677":3,"GO:0046898":1,"GO:2000767":1,"GO:0001514":1,"GO:1902802":1,"GO:0045901":1,"GO:0000288":1,"GO:0006413":1,"GO:0070125":1,"GO:0002184":1,"GO:0019079":1,"GO:0014009":1,"GO:0006449":1,"GO:0032790":1},"recipe_readded":[]}