{"hash":"1775274853617190552","title":"Nutrient-Responsive Fungal Growth and Secretion","description":"The top GO terms point to a fungal morphogenesis program triggered by nutrient limitation (pseudohyphal and invasive growth in response to glucose limitation) and to activation of secretory/trafficking processes (protein exit from ER, localization to the cell surface, secretion of lysosomal enzymes). Lipid metabolism terms (cholesterol, lipoprotein, fatty acid biosynthesis) suggest accompanying metabolic remodeling. Together, these terms imply a coordinated growth form switch in response to nutrients with associated secretion and lipid handling.","confidence":"Medium","size":11,"edges":10,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"XP_004912067.1","go_terms":["GO:0034447","GO:0034379","GO:0051005","GO:0042157","GO:0010900","GO:0048261","GO:0032375","GO:0033700","GO:0006641","GO:0034369","GO:0010916","GO:0008203","GO:0034382","GO:0033344","GO:0045717"]},{"accession":"XP_002936057.2","go_terms":["GO:0075015","GO:0006031","GO:0001744","GO:0007299","GO:0042248","GO:0000916","GO:0000918","GO:0000920","GO:0071555","GO:0034217","GO:0070592","GO:0071769","GO:0045227","GO:0052573","GO:0036108","GO:0016266","GO:0030244","GO:0019350","GO:0006011","GO:0018242","GO:0018243","GO:0030213","GO:0002378"]},{"accession":"XP_031751196.1","go_terms":[]},{"accession":"XP_004919217.1","go_terms":[]},{"accession":"XP_031754952.1","go_terms":[]},{"accession":"XP_031754954.1","go_terms":[]},{"accession":"NP_001032343.1","go_terms":[]},{"accession":"XP_002939067.1","go_terms":["GO:0007124","GO:0001403","GO:2000010","GO:0033299","GO:0061060","GO:0070863"]},{"accession":"XP_004910672.1","go_terms":[]},{"accession":"XP_004920377.1","go_terms":[]},{"accession":"XP_002936010.2","go_terms":["GO:0007124","GO:0001403","GO:2000010","GO:0033299","GO:0061060","GO:0070863"]}],"graph":[["XP_031751196.1","XP_031754952.1",0.614],["XP_031751196.1","XP_031754954.1",0.588],["XP_002939067.1","XP_002936010.2",0.532],["XP_002939067.1","XP_031754954.1",0.506],["XP_031754952.1","XP_004910672.1",0.548],["XP_031754952.1","XP_004919217.1",0.535],["XP_031754952.1","XP_004920377.1",0.534],["XP_031754954.1","XP_004910672.1",0.501],["XP_031754954.1","XP_004919217.1",0.596],["XP_031754954.1","XP_004920377.1",0.585]],"all_go_terms":{"GO:0045717":1,"GO:0042157":1,"GO:0048261":1,"GO:0008203":1,"GO:0034379":1,"GO:0034447":1,"GO:0033700":1,"GO:0006641":1,"GO:0033344":1,"GO:0010900":1,"GO:0010916":1,"GO:0032375":1,"GO:0051005":1,"GO:0034382":1,"GO:0034369":1,"GO:0000916":1,"GO:0075015":1,"GO:0030213":1,"GO:0071769":1,"GO:0018242":1,"GO:0070592":1,"GO:0045227":1,"GO:0030244":1,"GO:0019350":1,"GO:0006011":1,"GO:0034217":1,"GO:0000918":1,"GO:0000920":1,"GO:0016266":1,"GO:0071555":1,"GO:0036108":1,"GO:0007299":1,"GO:0002378":1,"GO:0018243":1,"GO:0006031":1,"GO:0001744":1,"GO:0042248":1,"GO:0052573":1,"GO:0007124":2,"GO:2000010":2,"GO:0001403":2,"GO:0061060":2,"GO:0033299":2,"GO:0070863":2},"recipe_readded":["XP_002934135.3","XP_004917157.1","XP_012814778.1","XP_031751341.1","XP_031760856.1","XP_012817612.2","NP_001004943.1","NP_001120271.1","XP_004911179.1","XP_031760465.1","NP_001016287.1","XP_012820880.2","XP_031751011.1","XP_031756401.1","XP_031758737.1","XP_017950423.1","NP_001016127.1","NP_001163968.1","NP_001016260.1","XP_031752706.1"]}